Hematology & Immunology Flashcards

(47 cards)

1
Q

Fluid Portion of the Blood (approx 55% of the Blood);

This suspends various protein

A

Plasma

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2
Q

A Function of Albumin

A

Maintains Oncotic Pressure;
If blood has low OP, fluid will leak to inappropriate areas

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3
Q

The Cellular Component of the Blood

A

RBCs (erythrocyte - 45% of the Blood)
WBCs (leukocyte - buffy coat + platelets)
Platelets (thrombocytes - fragments of megakaryocytes)

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4
Q

Lifespan of Platelts

A

10 days

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5
Q

Lifespan of RBCs

A

120 days

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6
Q

A complex process of the formation and maturation of blood cells

A

Hematopoiesis

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7
Q

The balance between CLOT (Thrombus) FORMATION and CLOT DISSOLUTION or Fibrinolysis

A

Hemostasis in the Blood

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8
Q

Two Types of Bone Marrow

A

Red & Yellow BM

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9
Q

Site of Hematopoiesis

A

Red Bone Marrow

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10
Q

Other sites of Hematopoiesis BEFORE BIRTH

A

Liver, Spleen, Thymus, Lymph Nodes of a Fetus

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11
Q

Also known as Fat Cells

A

Yellow Bone Marrow

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12
Q

It can turn into Red Bone Marrow in response to Emergency Cases

A

Yellow Bone Marrow

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13
Q

Known as “Mother Stem Cells” in the Red Bone Marrow

A

Pluripotent Stem Cells

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14
Q

These differentiate into Myeloid Stem Cell and Lymphoid Stem Cell

A

Pluripotent Stem Cells

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15
Q

Contains the Oxygen-Carrying Protein in the RBC

A

Hemoglobin

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16
Q

It contains a pigment that gives whole blood its red color

A

Hemoglobin

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17
Q

Composed of 1 globin (protein/polypeptide chain)
and 4 heme (ring like nonprotein pigment ring with an Iron ion)

A

Hemoglobin

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18
Q

O2 molecule binds with ___ and CO2 binds with ___

A

O2 - Iron
CO2 - globin

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19
Q

Refers to the percentage of Total Blood Volume occupied by RBCs

20
Q

It can affect production of Erythropoietin

21
Q

The reason why Males have higher Hct levels than Females

22
Q

Low Hct can indicate what

23
Q

High levels of Hct

24
Q

The reason why the shape of RBCs is as it is

A

No Nucleus and they cannot repair themselves

25
The rate of RBC formation by RBM equals the rate of RBC destruction by Macrophages
Erythropoiesis
26
Gives the color of the Feces
Stercobilin
27
Gives color to the Urine
Urobilin
28
Increased WBC
Leukocytosis
29
Use of Erythropoietin of Athletes; Hormones released by kidneys for Blood Production
Blood Doping (Peptides)
30
Decreased WBC
Leukopenia
31
31
Normal Range Values of WBC
5000-10,000
32
Normal Range of Platelets
150,000 - 400,000 platelets; Granules contain chemicals that once released, promotes Clotting
33
A sequence of responses that stops bleeding/hemorrhage
Hemostasis regarding Platelets “Clotting Cascade”
34
Hemostasis involving Platelets “Clotting Cascade”
1. Vascular Spasm 2. Platelet Plug Formation 3. Coagulation
35
= cessation of bleeding
Hemostasis
36
When bleeding occurs, blood needs to ______ to slow/stop; means clotting or coagulation)
Thicken, because remains relatively thin
37
Known as Factor I in the ClottingCascade
Fibrinogen
38
Activated factor I is aka
Fibrin - Fibrin Strands - Fibrin Mesh
39
Aka Factor II
Prothrombin
40
Activated Factor II that binds with ionized calcium (Ca++) to form Fibrin
Thrombin
41
Known as Tissue Factor Pathway (Tissue Thromboplastin) activated by damage/injury to the Tissues
Extrinsic Pathway
42
44
Excessive use of Erythropoietin can lead to formation of what; its can also increase heart pumping (overworked heart muscles)
Blood Clots - Blood Doping
45
Helps in increasing rate of Erythropoiesis
High Altitude / Mountain range TRAINING due to low concentration of O2
46
A special organ in a fluid state
Blood
47
Marrow Activity located where
Pelvis Ribs Vertebrae Sternum