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Master The Boards > Heme > Flashcards

Heme Flashcards

(59 cards)

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1
Q

Initial test for anemia

A

CBC

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2
Q

Accurate test for iron deficiency anemia

A

BM biopsy for stainable Fe

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3
Q

Treatment for iron deficiency anemia

A

Oral Fe Sulfate > IM

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4
Q

Accurate test for sideroblastic anemia

A

Prussian blue for ringed sideroblasts

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5
Q

Accurate test for thalassemia

A

Hb electrophoresis

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6
Q

Accurate test for B12 deficiency

A

Ab testing (pernicious)

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7
Q

Treatment for b12 deficiency

A

1 B12 shot per month

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8
Q

Treatment for folate deficiency

A

Daily oral folate

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9
Q

Initial test for macrocytic anemia

A

Peripheral smear (visualize hypersegmented neutrophils)

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10
Q

Treatment for stroke due to SCD

A

Exchange transfusion

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11
Q

Initial test for SCD

A

Peripheral smear (Howell jolly bodies)

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12
Q

Accurate test for SCD

A

Hb electrophoresis

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13
Q

Treatment for Parvo B19 in SCD

A

IVIG

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14
Q

Accurate test for ParvoB19

A

PCR

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15
Q

Treatment for SCD that improves mortality

A

Hydroxyurea + Abx in fever

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16
Q

Accurate test for hereditary spherocytosis

A

Osmotic fragility test

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17
Q

Treatment for hereditary spherocytosis

A

Folic acid + splenectomy

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18
Q

Accurate test for AI hemolysis

A

Coombs (IgG)

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19
Q

Treatment for AI Hemolysis

A

Glucocorticoids > IVIG > Splenectomy > Rituximab

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20
Q

Accurate test for cold agglutins disease

A

Cold agglutins titer

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21
Q

Treatment for cold agglutins disease

A

Stay warm + Rituximab

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22
Q

Initial test for G6PDD

A

Smear to look for Heinz bodies + bite cells

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23
Q

Accurate test for G6PDD

A

G6PD level 1-2 months later

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24
Q

Treatment for HUS/TTP

Study These Flashcards
A

plasmapheresis

25
Accurate test for PNH
Flow cytometry (decreased CD55/59)
26
Treatment for PNH
Prednisone > BMT > Eculizumab
27
Accurate test for aplastic anemia
BM biopsy
28
Treatment for aplastic anemia
Transfusion + Abx + platelets (acute)BMT (young)ATG + Cyclosporine (old)
29
Accurate test for PV
JAK2 mutation
30
Treatment for PV (4)
Phlebotomy/ASA + hydroxyurea + allopurinol + antiHis
31
Treatment for ET (2)
Hydroxyurea + ASA
32
Treatment for AML
ATRA
33
Initial test for leukemia
Blood smear (shows blasts)
34
Accurate test for leukemia
Flow cytometry
35
Additional treatment for ALL vs AML
Intrathecal MTX
36
Treatment for stage 3/4 CLL
Fludarabine + cyclophosphamide + Rituximab
37
Accurate test for CML
FISH/PCR (for bclABL)
38
Treatment for CML
Imatinib > BMT
39
Treatment for leukostatsis rxn
Leukophoresis
40
Treatment for 5q deletion causing myelodysplastic syndrome
Lenalidonide
41
Initial test for hairy cell
Smear
42
Accurate test for hairy cell
Flow cytometry
43
Treatment for hairy cell
Cladribine or Pentostatin
44
Initial test for NHL
Excisional biopsy
45
Treatment for stage 3/4 NHL
Rituximab + CHOP (cyclophosphamide/Adramycin/Vincristine/Prednisone)
46
Treatment for HL
ABVD (Adramycin/Bleomycin/Vinblastine/Dacarbazine)
47
Initial test for MM (2)
SPEP (IgG or IgA) + X-ray showing lytic lesions
48
Accurate test for MM
BM biopsy shows >10% plasma cells
49
Treatment for Waldenstrom
Plasmapheresis
50
Treatment for ITP
Steroids > IVIG > splenectomy > Romiplastin
51
Treatment for vWD
DDAVP > Factor 8
52
Accurate test for hemophilia
Specific assay for factors 8 and 9
53
Treatment for hemophilia
DDAVP > Factor 8 + 9
54
Treatment for DIC
FFP > Cryo
55
Treatment for HIT
Stop Hep + direct inhibitor + Warfarin
56
Accurate test for HIT (2)
ELISA (PF4 abs)Serotonin release assay
57
Accurate test for APS
Russell viper venom
58
Initial test for APS
PTT elevated which does not correct
59
Treatment for APS
Hep/Warfarin forever

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