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Heme Flashcards

(77 cards)

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1
Q

Whats the anticoagulant of choice for CBC

A

EDTA

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2
Q

Whats the anticoagulant of choice for PLT clumping

A

Sodium Citrate

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3
Q

What should be done when EDTA PLT clumping

A
  1. Draw a sodium citrate tube along with a EDTA tube

2. Run and multiply the result by 1.1

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4
Q

Hematocrit

A

packed cell volume

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5
Q

What affect the hematocrit

A

number of RBCs and their size.

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6
Q

Reticulocytes

A

immature RBCs with remanant of basophilic RNA.

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7
Q

Function of retic test

A

to evaluate the bm ability to produce RBCs in bone marrow transplant patients or post treatment.

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8
Q

Whats the unit of retics

A

%

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9
Q

Eos function

A

kill parasites and contribute to allergic reactions

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10
Q

Monocytes

A

consume dead or damaged cells

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11
Q

Lymph

A

protect the body against viruses, bacteria and fungi

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12
Q

type of lymph

A

T cells
B cells
NK - natural killers

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13
Q

T cells

A

directly attack viruses and bacteria and stimulate B cells

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14
Q

B cells

A

produces antibodies that attacks and destroy bacteria and viruses

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15
Q

Natural killer

A

detect and destroy abnormal tissue cells

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16
Q

Baso

A

release histamines during allergic reactions

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17
Q

Neutrophils

A

protect from bacterial infections

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18
Q

MCV

A

measurement of the average size of RBCs

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19
Q

MCV formula

A

hct/RBC *10

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20
Q

MCV unit

A

fL

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21
Q

What does MCV determines

A

Microcytic
Macrocytic
Normocytic

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22
Q

When is Microcytic seen

A

IDA

Thalassemia

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23
Q

When is Macrocytic seen

A

Megaloblastic anemia
alcoholism
new babies

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24
Q

MCH

A

average size of hgb

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25
MCH formula
hgb/rbc * 10
26
MCH unit
pg
27
MCHC
average of hgb compared to their size
28
MCHC formula
hgb/hct *100
29
MCHC unit
g/dL
30
RDW
reflects variation of RBCs size
31
what RDW stands for
Red blood cells Distribution Width
32
RDW unit
%
33
MPV
average size of plt
34
MPV unit
fL
35
When do you see micro/hypo
IDA Thalassemia Chronic infection Inflammation
36
When do you see normocytic/normochromic
leukemia bm failure chronic renal disease
37
When do you see macro/normochromic
liver disease myelodysplasias megaloblastic anemia
38
Schistocytes
RBCs cells fragments caused by fibrin shearing the cells
39
When do you see Schistocytes
DIC HUS TTP
40
Acanthocyte
irregular variably sized spicules
41
When do you see Acanthocyte
Lipid disorders | alcohol cirrhosis
42
Howell jolly body
residual nuclear material
43
Spherocyte
little or no central pallor
44
When do you see spherocyte
abo incompatability | hereditary spherocytosis
45
Dhole body
small blue inclusions in neutrophils indicating toxic change
46
when do you see dhole body
bacterial infections | burns
47
shift to the left
immature cells forms in blood
48
what does cytosine indicates
increase
49
target cells
bulls eye known as codocytes
50
when do you see target cells
thalassemia and hgb c disease
51
stomatocytes
central pallor looks like a head of a screw
52
Tear cell
known as dacrocyte
53
When do you see tear cell
megaloblastic anemia and myelofibrosis
54
Burr cell
regularly spaced projections
55
when are Burr cells seen
uremia and ulcers
56
Rouleaux
red cell stack of coins
57
When do you see Rouleaux
multiple myeloma and increased fibrinogen
58
Agglutination
red cells are in irregular clumps
59
when do you see Agglutination
cold agglutination or autoantibodies
60
Polychromasia
red cells that are bluish indicating young RBCs and acute blood loss
61
Poikilocytosis
variation in rbc shape
62
auer rods
seen in aml
63
smudged cells
fragile cells seem in CLL
64
Vaculated segs
seen in bacterial infections and sepsis
65
toxic granulation
dark staining granulation seen in bacterial infections and sepsis
66
pelger huet anomaly
bi-lobe seg or hyposeg
67
hypersegmented
>5 lobes seen in megaloblastic anemia
68
Giant plt
seen in CML and soulier syndrome
69
Baso stippling
fine purple staining granules
70
seen in basos
lead poisoning and thalassemai
71
Howell Jolly bodies
rbcs inclusion composed of DNA
72
When do you see Howell jolly bodies
sickle cell and thalassemia
73
Cabot rings
rbc inclusion composed of nuclear remnants
74
when do you see cabot rings
thalassemia and lead poisoning
75
Heins bodies
rbc inclusions composed of denatured hgb
76
absolute neutrophil count
WBCs * %neutrophils (all stages) | seg, bands, metas, myeloma and pro
77
Normal MCV and elevated RDW
seen un b12 or folate deficiency

Hematology (1 decks)

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