Heme/Onc Tx

Question 1

AML Induction Therapy

Answer 1

3 days of an Anthracycline + 7 days of cytarabine

Question 2

AML Consolidation Chemo

Answer 2

3-4 cycles of cytarabine high dose over 5 days in conjuction with etoposide, daunomycin or idarubicin

Question 3

ALL Induction Therapy (Philadelphia chromosome)

Answer 3

Gleevec (imatinib)

Question 4

ALL Induction Therapy

Answer 4

Oncovin® (vincristine), Elspar® (L-asparaginase) or Oncaspar® (peg-L-asparaginase), and an anthracycline such as Adriamycin® (doxorubicin)

Question 5

Older Pt with ALL

Answer 5

Hyper-CVAD (cyclophosphamide, vincristine, doxorubicin, dexamethasone)

Question 6

ALL Induction Therapy Children

Answer 6

administering three drugs: Oncovin® (vincristine), prednisone or dexamethasone, and Elspar® (L-asparaginase) or Oncaspar® (PEG-L-asparaginase).

Question 7

CLL Early Stage (Rai 0-II; Binet A)

Answer 7

NOTHING unless high risk/symptomatic

Question 8

CLL Symptomatic single chemotherapy agent

Answer 8

Leukeran® (chlorambucil) and Fludara® (fludarabine), Rituxan® (rituximab), Campath® (alemtuzumab), and Treanda® (bendamustine).

Question 9

CLL Symptomatic multitherapy Tx

Answer 9

Fludara; Cytoxan; Rituxan; Mitoxantrone; Campath
Fludara plus Cytoxan (FC);
Fludara, Cytoxan, and Rituxan (FCR);
Fludara, Cytoxan and Mitoxantrone (FCM) with or without Rituxan;
Fludara, Cytoxan, and Campath (FCC)
Cytoxan, Fludara, Campath and Rituxan (CFAR)
Nipent, Cytoxan and Rituxan (PCR)

Question 10

CLL supportive care

Answer 10

Intravenous Immunoglobulin
cotrimoxazole----Pneumocystis carinii
valganciclovir-----Cytomegalovirus
Systemic/broad spec antibiotics----Bacterial Infections
Antifungals----PRN for fungal infections
Neulasta or Neupogen-----Neutropenia
Epogen----Anemia

Question 11

CML Chronic phase

Answer 11

Gleevec or Tasigna

Question 12

CML Accelerated phase (after Gleevec failure)

Answer 12

Tasigna or Sprycel

Question 13

CML Blastic phase (after Gleevec failure)

Answer 13

Sprycel or Nilotinib

Question 14

Anal CA Tx

Answer 14

surgery, radiation therapy, or chemotherapy

Question 15

Anemia Tx

Answer 15

Dietary/supplements: B12, folic acid, iron, and vitamin C
Medication: vitamin B12 injections, folic acid pills, intravenous iron or oral iron pills, antibiotics, or hormones.
Blood transfusions, or surgery.

Question 16

Barrett’s Esophagus Tx

Answer 16

Anti-reflux medication—Without dysplasia
Anti-reflux medication possibly photodynamic/laser—-Low-grade dysplasia
Esophagectomy—-High-grade dysplasia

Question 17

Esophageal CA Stage 0-II

Answer 17

Esophagectomy

Question 18

Esophageal CA Stage III

Answer 18

Neoadjuvant chemotherapy and radiation followed by surgery

Question 19

Esophageal CA Stage IV

Answer 19

Multiple palliative measures, chemotherapy, radiation, surgery

Question 20

Esophageal CA chemotherapy Tx

Answer 20

Fluorouracil and Mutamycin®

Question 21

Bladder CA Stage 0-I

Answer 21

Transurethral Resection (TUR); Bladder Instillation of Bacille Calmette-Guérin (BCG)

Question 22

Bladder CA Stage II-III

Answer 22

Cystectomy; Neoadjuvant Chemo+Cystectomy

Question 23

Bladder CA Stage IV

Answer 23

Palliative chemotherapy +/- surgery

Question 24

Bladder CA Chemo

Answer 24

GC: Gemzar® (gemcitabine) and cisplatin.
MVAC: methotrexate, vinblastine, doxorubicin, and cisplatin.

Question 25

Brain CA

Answer 25

Surgery and or External Beam Radiation Therapy (EBRT)

Question 26

Breast CA chemo

Answer 26

Cyclophosphamide, doxorubicin, fluorouracil, methotrexate, Taxotere CMF: cyclophosphamide, methotrexate and fluorouracil CAF: cyclophosphamide, doxorubicin, and fluorouracil AC: doxorubicin and cyclophosphamide TAC: Taxotere, doxorubicin, cyclophosphamide

Question 27

What adjuvant to Stage II-IV Breast CA can be used?

Answer 27

Taxanes (Taxotere; Taxol)

Question 28

Breast CA Adjuvant

Answer 28

Taxanes Estrogen modulator (Tamoxifen, Aromatase inhibitors) HER2 (Herceptin)

Question 29

Premenopausal Estrogen modulation

Answer 29

Tamoxifen

Question 30

Postmenopausal Estrogen modulation

Answer 30

Aromatase inhibitor +/- Tamoxifen

Question 31

Cervical CA Stage 0-1 Tx

Answer 31

Total hysterectomy or conization surgery

Question 32

Cervical CA Stage 2-4 Tx

Answer 32

Chemo/Radiation

Question 33

Cervical CA Chemo

Answer 33

Platinol®, 5-fluorouracil

Question 34

Colon CA Stage I-III

Answer 34

Surgery + Adjuvant Chemo

Question 35

Colon CA Stage IV

Answer 35

Chemo + Avastin

Question 36

Colon CA Chemo Adjuvant

Answer 36

FOLFOX (LV/5-fluorouracil + Eloxatin (oxaliplatin) CAPEOX (Xeloda (capecitabine) + Eloxatin Xeloda

Question 37

Colon CA Chemo Stage IV

Answer 37

FOLFOX (LV/5-fluorouracil + Eloxatin (oxaliplatin) CAPEOX (Xeloda (capecitabine) + Eloxatin) FOLFIRI (LV/5-fluorouracil + Camptosar (irinotecan) FOLFOXIRI (LV/5-fluorouracil + Camptosar + Eloxatin

Question 38

Essential Thrombocytopenia

Answer 38

Low-dose-aspirin; Hydroxyurea

Question 39

Myelofibrosis

Answer 39

``` Jakafi Androgens Immunomodulators Hydroxyurea Blood Transfusions Splenectomy ```

Question 40

Polycythemia Vera

Answer 40

Phlebotomy Low-dose-aspirin Hydroxyurea

Question 41

Ewing Sarcoma Localized

Answer 41

Surgery, Radiation, Chemo

Question 42

Ewing Sarcoma Metastatic

Answer 42

Chemo

Question 43

Ewing Sarcoma Chemo

Answer 43

vincristine, actinomycin D, cyclophosphamide, and doxorubicin with alternating cycles of ifosfamide and etoposide