Heme Surface Markers Flashcards

1
Q

B cell

A

CD20
CD45
CD79a

Ig kappa
Ig lambda

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2
Q

T cell

A
CD3
CD7
CD4
CD8
CD45
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3
Q

CD34+

CD38-

A

blast

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4
Q

CD33 +

A

myeloid blast (maturing granulocyte)

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5
Q

CD33+
CD34+
CD13+
HLA-DR+

A

AML with t(15, 17)

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6
Q
CD34+
CD33+
CD17+
CD13+
CD14+
CD11b+
A

AML with inv (16, 16)

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7
Q

CD10+
CD19+
TdT+

A

ALL with t(9, 22)

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8
Q

CD10-
CD19+
TdT+

A

ALL with t(v, 11q23)

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9
Q

CD3+
CD5+
TdT+

A

T-ALL

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10
Q

CD117+
CD25+
Trypase +

A

mastocytosis (cKIT mutor FIP1 translocation)

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11
Q

Markers that differentiate between AML and ALL

A

AML: CD33, 13, HLA-DR, MPO

ALL: CD19, 10, 20, TdT

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12
Q

CDs assc with B cells in germinal centers

A

CD10

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13
Q

CDs assc with B cells in germinal centers and mantle zones

A

CD10

CD19

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14
Q

CDs assc with T cells in paracortex

A

CD3

CD5

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15
Q

CD38+

A

marker that somatic hypermuatation occurred

BAD prognosis

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16
Q

CD5+
CD23+
light chain restricted

A

CLL/SLL

17
Q

CD38+
CD138+
CD19-
CD20-

A

plasma cell neoplasm

18
Q
CD19+
CD20+
CD10+
CD22+
CD79a+
Bcl-2+
Surface Ig+

CD5-

A

Follicular Lymphoma

19
Q

CD30+
CD15+
CD20-

A

classical hodgkin

20
Q

CD20+
CD30-
CD15-`

A

NLP hodgkin

21
Q

CD19+
CD20+
CD22+
CD79a+

CD5/-
Surface Ig +/-
CD10 +/-

A

Diffuse large B cell lymphoma

22
Q
CD10+
CD19+
CD20+
CD22+
CD79+
surface IgM+

CD5-
CD23-

A

Burkitt’s Lymphoma