Heme synthesis

Question 1

First step?

Answer 1

Succinyl CoA and glycine

Question 2

Succinyl CoA and glycine turns into? (This is the 2nd step)

Answer 2

ALAS2, Succinyl CoA synthase, pyridoxal phosphate (3rd step)

Question 3

What does ALAS2, Succinyl CoA synthase, pyridoxal phosphate use for next step?

Answer 3

ALA (4th step)

Question 4

ALA turns into?

Answer 4

ALA dehydrase (5th step)

Question 5

ALA dehydrase turns into?

Answer 5

PBG (Porphobilinogen) (6th step)

Question 6

PBG uses what for the next step?

Answer 6

PBG deaminase (7th step)

Question 7

PBG deaminase turns into?

Answer 7

Hydromethylbilane (8th step)

Question 8

Hydromethylbilane has two pathways:

Answer 8

Uroporphyringen III and spontaneous (9th step)

Question 9

Spontaneous turns into?

Answer 9

Uroporphyrinogen I cosynthase and Coporphyrinogen I

Question 10

Uroporphyrinogen I cosynthase turns into?

Answer 10

Uroporphyrinogen III and Coporphyrinogen III (10th step)

Question 11

Coporphyrinogen III turns into?

Answer 11

Coporphyrinogen oxidase (11th step)

Question 12

Coporphyrinogen oxidase turns into?

Answer 12

Protoporphyrinogen IX (12th step)

Question 13

Protoporphyrinogen IX uses what for the next step?

Answer 13

Protoporphyrinogen oxidase (13th step)

Question 14

Protoporphyrinogen oxidase turns into?

Answer 14

Protoporphyrin IX (14th step)

Question 15

Protoporphyrin IX turns into?

Answer 15

Ferrochelatase (15th step)

Question 16

Ferrochelatase turns into?

Answer 16

Heme (Final step)