Heme Unit -Coagulation Disorders

Question 1

What medications cause hypercoagulable states?

Answer 1

OCP (oral contraceptive pills) and HRT (hormone replacement therapy). Others non drug= immobolization such as leg in cast

Question 2

Saddle Embolus

Answer 2

Occlusion of both L & R main pulmonary arteries (fatal pulmonary embolus)

Question 3

Cor Pulmonale

Answer 3

Right sided heart failure that occurs secondary to lung disease. Can occur with a pulmonary embolus

Question 4

Monckeberg’s Atherosclerosis

Answer 4

Calcification within the vessels that leads to brittle/thin vessels that crack and activate plts and coag pathways. Mechanism for Thrombosis in the Arterial system

Question 5

Lines of Zahn

Answer 5

Characteristic of Arterial Thrombosis. Soft and dark red with alternating bands of yellow platelets and fibrin seen on pathology autopsy.