Hemodynamic Effects of Various Cardiovascular Agents Flashcards
Table 6-3 Barrons p. 153 (17 cards)
Parameters
BP:
CVP:
PAP:
PAOP:
CO/CI:
SV/SI:
SVR:
PVR:
HR:
~ = no change
↑ = increase
↓ = decrease
Dopamine Low Dose (1-3 mcg/kg/m)
BP: ~
CVP: ~
PAP: ~
PAOP: ~
CO/CI: ~
SV/SI: ~
SVR: ~
PVR: ~
HR: ~
Dopamine Medium dose (4-10 mcg/kg/m)
BP: ~ or ↑
CVP: ~
PAP: ~ or ↑
PAOP: ~ or ↑
CO/CI: ↑↑
SV/SI: ↑
SVR: ~
PVR: ~
HR: ↑
Dopamine High Dose (11-20 mcg/kg/m)
BP: ↑
CVP: ~ or ↑
PAP: ↑
PAOP: ↑
CO/CI: ↑
SV/SI: ↑
SVR: ↑
PVR: ↑
HR: ↑↑
Norepinephrine (Levophed)
BP: ↑
CVP: ↑ or ~
PAP: ↑
PAOP: ↑
CO/CI: ↑
SV/SI: ↑
SVR: ↑↑
PVR: ~ or ↑
HR: ~
Phenylephrine (Neo-Synephrine)
BP: ↑
CVP: ~
PAP: ~
PAOP: ~ or ↑
CO/CI: ~
SV/SI: ↑
SVR: ↑
PVR: ~
HR: ~
Epinephrine gtt
BP: ↑
CVP: ↑ or ~
PAP: ↑
PAOP: ↑
CO/CI: ↑
SV/SI: ↑
SVR: ↑↑
PVR: ~ or ↑
HR: ↑
Nitroglycerin (up to 1mcg/kg)
BP: ~ or ↓
CVP: ↓
PAP: ↓
PAOP: ↓↓
CO/CI: ~
SV/SI: ~
SVR: ~
PVR: ~ or ↓
HR: ~ or ↑
Nitroglycerin >1mcg/kg
BP: ↓
CVP: ↓
PAP: ↓
PAOP: ↓
CO/CI: ~ or ↑
SV/SI: ~ or ↑
SVR: ↓
PVR: ↓
HR: ~ or ↑
Nesiritide (natrecor)
BP: ~ or ↓
CVP: ↓
PAP: ↓
PAOP: ↓
CO/CI: ~ or ↑
SV/SI: ~ or ↑
SVR: ↓
PVR: ↓
HR: ~
Nitroprusside (Nipride)
BP: ↓↓
CVP: ↓
PAP: ↓
PAOP: ↓↓
CO/CI: ~ or ↑
SV/SI: ~ or ↑
SVR: ↓↓
PVR: ↓
HR: ~ or ↑
ACE Inhibitors
BP: ↓
CVP: ~
PAP: ~
PAOP: ~ or ↓
CO/CI: ~ or ↑
SV/SI: ~ or ↑
SVR: ↓
PVR: ~
HR: ~
Dobutamine (Dobutrex)
BP: ~ or ↓ or ↑
CVP: ~
PAP: ~
PAOP: ↓
CO/CI: ↑
SV/SI: ↑
SVR: ~ or ↓
PVR: ~
HR: ↑
Milrinone (Primacor)
BP: ~ or ↓
CVP: ~ or ↓
PAP: ~ or ↓
PAOP: ↓
CO/CI: ↑
SV/SI: ↑
SVR: ↓
PVR: ~
HR: ~
Labetalol (Normadyne)
BP: ↓
CVP: ~
PAP: ~
PAOP: ~
CO/CI: ↓
SV/SI: ↓
SVR: ~ or ↓
PVR: ~
HR: ↓
Morphine
BP: ↓
CVP: ↓
PAP: ↓
PAOP: ↓
CO/CI: ~
SV/SI: ~
SVR: ~
PVR: ↓
HR: ~
Extra on high-dose NTG, nesiritide, and nitroprusside
They are afterload reducers, not positive inotropes, but they may increase CO indirectly by decreasing afterload
