Hemorrhagic virals

Question 1

What does all hemorrhagic viruses have in common?

Answer 1

Damage microvasculature leads to INC permeability

Question 2

Mosq, Truncal rash, LAD, Tourniquet test indicates

Answer 2

DF (DHF or DSS)

Question 3

HF involving Ticks/livestock?

Answer 3

Crimean/Congo HF

Question 4

What does a saddleback fever mean and for what infection?

Answer 4

Fever abates for a day then returns and it means this is the time you can develop DHF or DSS
YF transfers from acute to remit (1d) to toxic phase

Question 5

Is there a vaccine available for yellow fever?

Answer 5

Yes 1937

Question 6

How many serotypes of Dengue are there?

Answer 6

4 (DEN-2 most virulent)

Question 7

How long is E/M recovery?

Answer 7

months

Question 8

TXT Lassa w/

Answer 8

Ribavirin w/in 6D

aggressive support

Question 9

TXT Hantavirus w/

Answer 9

Fluids/Lytes
Support
RIbavarin

Question 10

3 phases of YF

Answer 10

Acute (3D)
Remit (1D - saddleback)
Toxic phase

Question 11

How often to monitor HCT w/ DF?

Answer 11

Q3-4hr

Question 12

Are humans a natural reservoir for VHFs?

Answer 12

No

Question 13

Swollen baby syndrome is due to what infection and causes what?

Answer 13

Lassa

Edema, Dist Abd, Anascara, Bld

Question 14

Saddleback fevers suggest

Answer 14

Dengue and yellow fever

Question 15

TXT E/M consist of

Answer 15

isolation
support- fluids and nutrition
human convalescent plasma

Question 16

Flaviviridae

Answer 16

Dengue

Yellow Fever

Question 17

Are hemorrhagic fever viruses DNA or RNA?

Answer 17

RNA

Question 18

Where does the YF virus replicate?

Answer 18

Overwhelms immune sys by Reticuloendothelial sys affecting liver (jaundice)

Question 19

What is the Tourniquet test for and how is it performed?

Answer 19

To test Dengue fever

Inflate BP cuff in upper arm between SBP and DBP and hold for 5m. POS= 20 petechiae per square inch

Question 20

What are important lab findings of E/M?

Answer 20

Metabolic acidosis and INC Bun/Creatinine

Question 21

Complications of Lassa

Answer 21

Fetal/maternal mortality

Deafness (MC)

Question 22

What precedes shock w/ DF?

Answer 22

Rise in HCT by 20 percent

Question 23

What are a common PE findings of E/M?

Answer 23

INC HR and RR

Question 24

Ghost like faces is a late finding of what infection?

Answer 24

E/M

Question 25

Two forms of yellow fever are?

Answer 25

Urban - Aedes Aegypti mosq (epidemic) | Jungle - various mosq

Question 26

Rodent resvoir and an ass/w deafness or fetal/maternal complications indicates?

Answer 26

LASSA

Question 27

What labs are low w/ DF

Answer 27

WBC - end of febrile phase PLT Na (MC- metabolic change) Albumin - Sign of hemoconc

Question 28

The significance of HCT w/ DF

Answer 28

INC 20 percent = hemoconcentration = oozing plasma | DEC 10 percent = significant hemorrhage = bleeding

Question 29

Important S/S of CCHF

Answer 29

Flu like then massive hemorrhage/bruising | Substantial GI bleeding

Question 30

Important E/M S/S

Answer 30

Rash over entire body Diarrhea Odynphagia/Dysphagia

Question 31

Bats, Primates, Rash over body, difficulty swallowing indicates

Answer 31

E/M

Question 32

INC WBC and HCT and K w/ DEC PLT and Na suggests

Answer 32

Hantavirus

Question 33

TXT DF

Answer 33

Self limit (APAP for fever)

Question 34

Complications of E/M

Answer 34

ocular issues, tinnitus, unilat orchitis

Question 35

Arenaviridae

Answer 35

Lassa fever

Question 36

Bunyaviridae virus strains

Answer 36

Crimean-Congo HF | Hantavirus

Question 37

Dx Lassa

Answer 37

IgG/IgM ELISA | PCR

Question 38

Trias of hanta virus

Answer 38

Fever Hemorrhage Renal insuff

Question 39

Flu like, ticks, and bruising indicates

Answer 39

CCHF

Question 40

TXT/PVT YF

Answer 40

support, central vein access FFP for active bleeds vaccine and deet

Question 41

Black water (BIlious) vomiting indicates

Answer 41

Membrane/GI bleed of Yellow fever

Question 42

TXT CCHF is

Answer 42

Ribavirin

Question 43

What labs are ABNL with Lassa

Answer 43

AST is high | DEC Lymph/PLT

Question 44

Rodent resivoir and an ass/w Asia or Renal insuff indicates

Answer 44

Hantavirus

Question 45

Filoviridae

Answer 45

Ebola | Marburg

Question 46

What does rash of DF look like?

Answer 46

Truncal Scarlatinaform rash/maculopapular

Question 47

Mosq, black water/bilious vomit, w/ cardiac/AMS changes indicates?

Answer 47

YF

Question 48

Important DF S/S

Answer 48

Truncal rash Retro-orbital pain Very high fever General LAD

Question 49

DX E/M

Answer 49

IgG/IgM Elisa or PCR

Question 50

What can a baby get if Lassa is contracted?

Answer 50

Swollen baby syndrome

Question 51

Hiccups is an indicator of what with what infection?

Answer 51

Indicates high mortality for E/M

Question 52

5 stages of HFRS

Answer 52

``` Febrile - bradycardic HOTN - tachycardic and shock w/ paralytic ileus Oliguric - HTN, uremia causing bleedsing Diuretic - rapid deyhdration Convalescent - 3-6mo ```

Question 53

Complication of CCHF is

Answer 53

Encephalitis (rare)

Question 54

Type of mosquito spreads Dengue Fever?

Answer 54

Aedes Aegypti (Albopictus) Day-bites

Question 55

Best way to PVT dengue is?

Answer 55

20-30% Deet

Question 56

Is bleeding common with LASSA?

Answer 56

No (rare)

Question 57

Important S/S of yellow fever

Answer 57

Bilious black water vomiting (acute) | AMS and cardiac changes (toxic)

Question 58

Complications of hantavirus

Answer 58

Pulm Edema and hypercalcemia

Question 59

HF commonly found in Asia

Answer 59

Hantavirus

Question 60

Are there cures for VHFs?

Answer 60

No

Question 61

What does the Rash of E/M look like?

Answer 61

Maculopapular rash over entire body

Question 62

Important adult S/S of Lassa

Answer 62

Insidious onset lumbar pain cough facial/neck edema

Question 63

Ribavirin is used to TXT what

Answer 63

LASSA Hantavirus CCHF

Question 64

TXT for DHF or DSS

Answer 64

IV fluids Bld transfusion (Whole blood) Gamma globulin

Question 65

What is ZMAPP?

Answer 65

Experimental drug used for E/M

Question 66

What are the forms of Dengue?

Answer 66

D. Fever - Asymp/symp (?) D. Hemorrhagic fever D. Shock Syndrome

Question 67

Resvoir for Ebola/marburg?

Answer 67

Bats (MC) and primates

Question 68

Dx DF

Answer 68

Viral Cx Serology - IgG or IgM(D5 to 3months) PCR - test during 1st week

Question 69

What infection is related to rodent to human transmission?

Answer 69

Lassa

Question 70

HF ass/w renal insuff

Answer 70

Hantavirus

Question 71

What is the resivoir of hantavirus?

Answer 71

Rodents (lassa has no renal issues)