Hemostasis

Question 1

Please describe the activation process of the thrombocytes!

Answer 1

Characteristics of platelets.
Adhesion (direct/indirect)
Agreggation
Activation
Regulation

Question 2

What happens in the advanced stage of the blood coagulation?

Answer 2

• Detailed description of the processes summarized on pages 37-41.
• Characterize the participating complexes as well!

Question 3

Please describe those processes which regulate the plasmin level!

Answer 3

From plasminogen to plasmin, plasminogen activators and their inhibitors (PAI, ADP, serotonin, adrenalin and TAFI)

Question 4

Which components make up the extrisic and intrinsic tenase complexes and the prothrombinase complex? What is the role of complex formation in the hemostasis?

Answer 4

Detailed characterization of the three complexes
* Role of complex formation: pages 46-49.
* The role of vitamin K

Question 5

Please describe the role of the blood vessels in keeping the blood in fluid state under normal conditions!

Answer 5

The role of the intact vessel endothelial in inhibiting the von Willebrand factor receptor-ligand interaction
* The role of the intact vessel endothelial in keeping the tissue factor from initiating the coagulation cascade