Hemostasis Flashcards

1
Q

What test monitors patients who are on Warfarin or Coumadin therapy?

A

PT/INR

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2
Q

What pathway does warfarin or Coumadin affect?

A

Extrinsic

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3
Q

What test monitors patients who are on heparin therapy?

A

PTT

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4
Q

What pathway does heparin affect?

A

Intrinsic

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5
Q

What anticoagulant is used for coagulation tests? What color vacutainer is it?

A

Sodium citrate / light blue tube

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6
Q

Coagulation tests are performed on?

A

Plasma

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7
Q

Why must blood collection for coagulation tests be performed carefully?

A

To ensure minimum trauma to veins and surrounding tissues that may release chemicals and result in activation of the coagulation pathway.

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8
Q

What are 2 inhibitors of platelet aggregation?

A

Plavix and aspirin

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9
Q

What does Coumadin/warfarin inhibit?

A

The production of vitamin K dependant factors

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10
Q

What does heparin inhibit?

A

Activate of some coagulation factors

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11
Q

What does a D-Dimer test detect?

A

The breakdown products of a blood clot.

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12
Q

Hemophilia A Is due to a deficiency of what?

A

Factor VIII

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13
Q

Hemophilia B is a deficiency of what?

A

Factor IX

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14
Q

What is the most common inherited platelet disorder?

A

Von willebrand’s disease (vWD)

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15
Q

What does Von Willebrand’s Disease affect?

A

Platelet adhesion

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16
Q

Hemostasis is a balance between?

A

Coagulation and fibrinolysis

17
Q

What are the 4 components of hemostasis?

A
  1. Blood Vessels
  2. Platelets
  3. Coagulation Factors
  4. Fibrinolysis
18
Q

What are the 3 coagulation pathways?

A
  1. Intrinsic Pathway
  2. Extrinsic Pathway
  3. Common Pathway
19
Q

The extrinsic pathway is activated by what?

A

Factor III

20
Q

What does the common pathway result in?

A

The formation of the stable fibrin clot.