Hepatic/Biliary Disorders Flashcards
(46 cards)
Hepatitis B
- transmitted primarily by blood
- long incubation period
- most develop antibodies and recover w/o complications
Risk Factors for Hep B
- blood transfusion
- frequent exposure to blood/blood products
- multiple sex partners
- IV drug use
Hep B S/S
- anorexia
- insomnia
- low grade fevers
- indigestion
- RUQ pain
- jaundice
- rashes
- arthralgia
Chronic Hep B Complications
- cirrhosis
- end stage liver disease
- death usually imminent w/in 1-3 yrs w/o successful liver transplant
- liver cancer
Hep B Prevention
- Hep B vaccine
- eliminate risky behavior
- Hep B hyperimmune globulin
When to get Hep B Hyperimmune Globulin
- post exposure prophylaxis for people at risk
- recently exposed to body fluids of individuals w/ Hep B
- babies of moms w/ hep , sexual partners, healthcare workers, police/fire men, morticians
Hep C
- occurs most commonly after IV drug use or blood transfusions (prior to 1992)
- multiple partners/needle sticks
- asymptomatic for decades
- leading cause of liver disease
Acute Hep C S/S
- jaundice
- n/v
- malaise
Chronic Hep C S/S
- usually on accidental findings or cirrhosis occurs
- jaundice
- bleeds/bruises easily
- dry/itchy skin
- ascites
- pedal edema
- hepatic encephalopathy
Alcoholic Hepatitis
over-ingestion of alcohol leads to liver disease
S/S of Alcoholic Hepatitis
- jaundice
- anorexia, n/v, abdominal pain
- spider angiomas
- palmar erythema
- enlarged liver or small & hardened
- splenic enlargement
- ascites, pedal edema, hepatic encephalopathy
Treatment for Alcoholic Hepatits
- alcohol cessation
- monitor for withdrawal
- rest
- adequate hydration
- treatment of symptoms
Alcohol Withdrawal Stage 1
- after 8 hrs
- anxiety
- insomnia
- nausea
- abdominal pain
Alcohol withdrawal Stage 2
- after 1-3 days
- high BP
- increased body temp
Alcohol Withdrawal Stage 3
- after 1 week
- hallucinations
- fever
- seizure
- agitation
Drug-Induced Hepatitis
-acute liver failure caused by ingestion of certain meds
What meds can cause drug-induced Hep?
- acetaminophen
- Dilantin
- statins
- sulfa antibiotics
S/S of Drug-Induced Hep
Abrupt -fever/chills -rash/itching -arthralgia -anorexia/nausea Late -jaundice -enlarged liver -dark urine
Treatment for Drug-Induced Hep
- discontinue offending meds
- antidote if available
- monitor liver damage-albumin, total protein
What is the antidote for acetaminophen?
oral mucomyst
Cirrhosis
final stage of chronic liver disease that results in scarring of the liver
- damage can not be undone but if treated early can be limited
- compensated and uncompensated
Compensated Cirrhosis
-liver can still do its job b/c there are enough healthy cells to make up for the damage and scarring
Uncompensated Cirrhosis
liver has to much scarring and patient develops complications
Compensated Cirrhosis S/S
-asymptomatic or vague early Later -intermittent low grade fevers -epistaxis -vascular spiders, palmer erythema -dyspepsia, mild abdominal pain