Hepatitis

Question 1

What is hepatitis?

Answer 1

Virus

Question 2

What are the types of hepatitis?

Answer 2

A
B
C
D
E

Question 3

What is hepatitis A?

Answer 3

RNA virus

Question 4

How is hep A spread?

Answer 4

Faecal-oral

Question 5

What are the symptoms of a hep A infection?

Answer 5

Fever
Malaise 
Nausea
Arthralgia 
Jaundice

Question 6

How is Hep A managed?

Answer 6

Supportive - usually self limiting

Avoid alcohol

Question 7

Is there a hep A vaccinatation?

Answer 7

Yes

Question 8

How can hep A be diagnosed?

Answer 8

IgM rises after day 25
IgG detectable for life
Serum transaminases rise 22-40 days after infection

Question 9

What is hep B?

Answer 9

DNA virus

Question 10

How is hep B spread?

Answer 10

IV drug use
Sexual contact
Direct contact
Blood products

Question 11

What are the symptoms of a hep B infection?

Answer 11

Fever
Malaise 
Nausea
Arthralgia 
Jaundice

Question 12

Who is at risk for hep B?

Answer 12

IV drug users
Health workers
Sexually promiscuous

Question 13

How can hep B be diagnosed?

Answer 13

HBsAg (surface antigen present for 1-6 months

HBeAg present 1-3 months after acute infection

Question 14

What do HBcAg antibodies show?

Answer 14

Past infection

Question 15

What do HBsAg antibodies show?

Answer 15

Vaccination

Question 16

What is the management for hep B?

Answer 16

Supportive

Avoid alcohol

Question 17

Is there a vaccine for hep B?

Answer 17

Yes

Question 18

What is hep C?

Answer 18

RNA flavivirus

Question 19

How is hep C spread?

Answer 19

Blood
IV drug use
Sexual contact

Question 20

How is hep C diagnosed?

Answer 20

Raised LFTs

Anti-HCV

Question 21

How is hep C managed?

Answer 21

Inteferon-a + ribavirin

Question 22

Is there a vaccine for hep C?

Answer 22

No

Question 23

What is hep D?

Answer 23

Incomplete RNA virus - only exists with hep B

Question 24

What is hep E?

Answer 24

RNA virus - similar to hep A