Flashcards in Hepatitis B Deck (11):
What cell types does it target?
Hepatocytes (liver cells)
What receptor is targeted?
How does the virus enter the cell?
How does HBV present?
Jaundice, liver problems
How is the genome structured?
In relaxed circular DNA form (ie there is a nick in one strand)
What type of genome is HBV?
What occurs in the nucleus?
RC DNA converted to cccDNA (covalently closed circular DNA) and binds histones to create a stable plasmid type structure.
Where does budding occur?
Does HBV contain reverse transcriptase?
Yes! It is carried inside the NC
What family is HBV in?