Hepatitis Viruses Flashcards Preview

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Flashcards in Hepatitis Viruses Deck (37)
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1
Q

Hepatitis with fecal-oral transmission

A

A, E
vowels hit your bowels yo
contaminated food

2
Q

Sexually Transmitted Hepatitis

A

B, C, D

3
Q

Common Presentation (Hep)

A

fever, jaundice, inc ALT/AST, RUQ pain

4
Q

HAV (short)

A

Asymptomatic, Acute, Alone (no carriers)

5
Q

HBV (short)

A

Blood, Baby-making, Birthing

6
Q

HCV (short)

A

Chronic, Cirrhosis, Carcinoma, Carrier

7
Q

HDV (short)

A

Defective virus, Dependent (on HBV)

superinfection means poor prognosis

8
Q

HEV (short)

A

Enteric, Expectant mothers (high mortality), Epidemic

9
Q

HBsAg
ABeAg
Anti-HBc IgM

A

Acute HBV infection

10
Q

HBsAg
HBeAg
Anti-HBc IgG

A

Chronic HBV with high infectivity

11
Q

HBsAg
Anti-HBe
Anti-HBc IgG

A

Chronic HBV with low infectivity

12
Q

Anti-HBs

A

vaccinated for HBV

13
Q

HBV incubation period test

A

HBsAg

14
Q

HBV prodrome, acute disease test

A

HBSAg (anti-HBc)

15
Q

HBV early convalescence

A

Anti-HBc

16
Q

HBV late convalescence

A

Anti-HBs (anti-HBc)

17
Q

Viral hepatitis vs. alcoholic hepatitis liver tests

A

viral: ALT>AST
alcohol: AST>ALT

18
Q

Which Hepatitis lead to chronic infection?

A

B,C,D

19
Q

Which Hepatitis are we immunized against?

A

A,B

20
Q

Which hepatitis usually resolves when infected as a healthy adult but almost always (90%) transform to chronic when transmitted at birth?

A

HBV

21
Q

Icteric phase of hepatits presentation

A
dark urine- Coca Cola
light feces
jaundice
pruritis
7-28 days after
22
Q

Acute hepatitis lab test always shows what?

A

increased aminotransferases

look at INR for marker of severity

23
Q

Most common Hep viruses in USA

A

B > A > C

24
Q

Fulminant Hepatitis

A

hepatic failure within 8 weeks of onset of acute hep
hepatic encephalopathy and prolonged PT
hepatic necrosis on histo

25
Q

Chronic viral hepatitis definition

A

elevated aminotransferase and/or viral markers present for >6 months
liver firbosis, cirrhosis, hepatocellular carcinoma

26
Q

HBV disease progression

A
Chronic
Cirrhosis
Liver Failure
Liver Cancer
Need transplant or die
27
Q

HBV disease progression

A
Chronic
Cirrhosis
Liver Failure
Liver Cancer
Need transplant or die
28
Q

HAV treatment

A

supportive care- 3 months till improvement
PREVENT with immune globulin pre-post exposure
vaccine

29
Q

For which Hepatitis should you be concerned about genotype?

A

HCV

30
Q

Hepatitis extrahepatic complication

A

cryoglomulinemia
autoimmune disease- thyroid
glomerular disease

31
Q

Hepatitis superinfection

A

previouslt infected with HBV then superinfected with HDV

high risk for severe chronic liver disease

32
Q

HEV complications

A

Neuro- GBS, parsonage tuner syndrome, mononeuropahty

asymptomatic

33
Q

HEV treatement

A

ribavirin for symptoms otherwise monitor

34
Q

signs of icteric phase

A

dark urine
light feces
jaundice
pruritis

35
Q

what is fulminant hepatitis?

A

hepatic failure within 8 weeks of acute hepatitis

diagnose by presence of hepatic encephalopathy and prolonged PT

36
Q

for which hepatitis can immune globulin be give prophylactically for travelling or personal contacts?

A

HAV

37
Q

chronic active vs. persistent hepatitis

A

active: HCC, ESLD, cirrhosis
persistent: polyarteritis nodosum, glomerulonephritis