Hhh Flashcards
(52 cards)
What must spermatozoa undergo to fertilize the oocyte?
Spermatozoa must undergo capacitation and the acrosome reaction to acquire the capability to fertilize the oocyte.
Where does capacitation occur?
Capacitation occurs in the uterine tube.
What happens during capacitation?
Glycoprotein coat and seminal plasma proteins are removed from the plasma membrane that overlies the acrosomal region of the spermatozoa.
What is the acrosome reaction?
The acrosome reaction occurs after binding of spermatozoa to the zona pellucida, culminating in the release of enzymes needed to penetrate the zona pellucida.
What are the phases of oocyte penetration?
Phase 1: Spermatozoa pass through corona radiata barrier.
Phase 2: One or more spermatozoa penetrate zona pellucida.
Phase 3: Fusion of oocyte and sperm cell membranes.
What happens immediately after a sperm enters the oocyte?
The zona pellucida and oocyte membrane become impenetrable to other spermatozoa.
What occurs after fertilization regarding the oocyte?
The oocyte finishes its 2nd meiotic division and forms the female pronucleus.
What happens to the sperm after it penetrates the oocyte?
The head of the sperm separates from the tail, which detaches and degenerates.
What forms the male pronucleus?
The sperm nucleus becomes swollen and forms the male pronucleus.
What must each pronucleus do during fertilization?
Each pronucleus must replicate its DNA.
What are the results of fertilization?
Restoration of the diploid number of chromosomes, determination of chromosomal sex, and initiation of cleavage.
What happens if fertilization does not occur?
The menstrual phase begins, shedding the spongy and compact endometrial layers while the basal layer remains to regenerate.
What is observed in the two-cell stage immediately after ovulation?
The oocyte shows the spindle of the 2nd meiotic division.
What happens in the two-cell stage after a spermatozoon penetrates the oocyte?
The chromosomes of the oocyte are arranged in a vesicular nucleus, the female pronucleus.
What occurs during the two-cell stage regarding DNA?
Male and female pronuclei replicate their DNA.
What happens to chromosomes during the two-cell stage?
Chromosomes become arranged on the spindle in the equator of the zygote.
What occurs after the completion of the first mitotic division of the zygote?
Two cells are produced.
What is cleavage?
Cleavage is a series of mitotic divisions that results in an increase in cells (blastomeres) which become smaller with each division.
What happens after three divisions of blastomeres?
Blastomeres undergo compaction to become a tightly grouped ball of cells with inner and outer layers.
When is the two-cell stage reached after fertilization?
The two-cell stage is reached approximately 30 hours after fertilization.
When is the four-cell stage reached after fertilization?
The four-cell stage is reached at approximately 40 hours after fertilization.
When is the 16-cell stage reached after fertilization?
The 16-cell stage is reached at approximately 3 days after fertilization.
What happens during the late morula stage?
The late morula stage is reached at approximately 4 days, and blastomeres are surrounded by zona pellucida.
What occurs during blastocyte formation?
The morula enters the uterus on the 3rd or 4th day after fertilization, and fluid begins to penetrate through the zona pellucida.