{ "@context": "https://schema.org", "@type": "Organization", "name": "Brainscape", "url": "https://www.brainscape.com/", "logo": "https://www.brainscape.com/pks/images/cms/public-views/shared/Brainscape-logo-c4e172b280b4616f7fda.svg", "sameAs": [ "https://www.facebook.com/Brainscape", "https://x.com/brainscape", "https://www.linkedin.com/company/brainscape", "https://www.instagram.com/brainscape/", "https://www.tiktok.com/@brainscapeu", "https://www.pinterest.com/brainscape/", "https://www.youtube.com/@BrainscapeNY" ], "contactPoint": { "@type": "ContactPoint", "telephone": "(929) 334-4005", "contactType": "customer service", "availableLanguage": ["English"] }, "founder": { "@type": "Person", "name": "Andrew Cohen" }, "description": "Brainscape’s spaced repetition system is proven to DOUBLE learning results! Find, make, and study flashcards online or in our mobile app. Serious learners only.", "address": { "@type": "PostalAddress", "streetAddress": "159 W 25th St, Ste 517", "addressLocality": "New York", "addressRegion": "NY", "postalCode": "10001", "addressCountry": "USA" } }
Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Drugs Pharm Quarter 3 > Histamine and 3 Toxicology Lectures > Flashcards

Histamine and 3 Toxicology Lectures Flashcards

(45 cards)

Start Studying
1
Q

What 6 drugs can mediate histamine release through non IgE pathway?

A 
d-tubocurare
succinylcholine
morphine
codeine
doxorubicin
protamine
Vancomycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What drug causes the side effect of red man syndrome?

A

Vancomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What two drugs stabilize mast cells, decrease allergic rhinitis symptoms, have prophylactic use to block asthmatic runs?

A

Cromolyn

Nedocromil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What 2 drugs can induce cytolytic release?

A

phenothiazines

narcotic analgesics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are 5 1st generation antihistamine drugs?

A 
Triprolidine
Diphenhydramine
Promethazine
Hydroxyzine
Chlorpheniramine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are 6 2nd generation antihistamine drugs?

A 
Ioratadine
Desloratadine
Terfenadine
Fexofendaine
Azelastine
Cetirizine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the active metabolite of loratadine?

A

desloratadine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the active metabolite of terfenadine?

A

fexofenadine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What two antihistamines were pulled from the market due to risk of life-threatening cardiac arrhythmias when taken with ketoconazole, erythromycin, and clarithromycin? They also cause torsades de pointes

A

Terfenadine

Astemizole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the most effective antihistamine for motion sickness?

A

promethazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are 4 antihistamines that prevent symptoms of motion sickness?

A

promethazine
diphenhydramine
cyclizine
meclizine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What anticholinergic drug is the most effective drug to prevent motion sickness?

A

scopolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What 2 drugs prevent N/V and are a part of the phenothiazine class?

A

promethazine

timeprazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What 2 antihistamines are used as sleep medications?

A

Diphenhydramine

Doxylamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What antihistamine is used for it’s antiparkinsonism effects?

A

Diphenhydramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are 2 drugs used for local anesthetic actions?

A

Promethazine

Diphenhydramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the 4 uses of Diphenhydramine besides using it as an antihistamine?

A

Motion sickness
Sleep medication
Antiparkinsonism effects
Local anesthetic actions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What antihistamine has 50-90% H1 receptors in CNS bound?

A

Doxepin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

This drug affects the alpha receptor for BP control and causes hemolytic anemia

20
Q

These 3 drugs cause lupus like syndrome

Study These Flashcards
A

Hydralazine
Isoniazid
Procainamide

21
Q

What 7 drugs can cause Stevens-Johnson Syndrome?

Study These Flashcards
A 
Barbiturates
Sulfonamides
Phenytoin
Carbamazepine
Allopurinol
NSAIDs
Penicillins
22
Q

What drug’s metabolite can cause liver damage?

Study These Flashcards
A

Acetaminophen

23
Q

What 5 drugs classes and 3 specific drugs cause progressive renal failure?

Study These Flashcards
A

Class: NSAIDs, ACEI, antibiotics, antineoplastic agents, immunomodulators
Specific: Gentamicin, Amphotericin B, Contrast Media

24
Q

What drug causes dose related nephrotoxicity?

Study These Flashcards
A

Contrast media

25
What drug causes high frequency of kidney injury because it's mechanism for efficacy is shared by mechanism responsible for toxicity?
Amphotericin B
26
What drug causes renal tubular injury reversible by cessation?
Gentamicin
27
What drug caues a production of reactive oxygen species which can be directly cytotoxic to myocytes?
Doxorubicin
28
What 2 drugs cause pulmonary fibrosis?
Bleomycin | Amiodarone
29
What drug causes emesis and vomiting within 20 minutes of taking?
Syrup of Ipecac
30
What drug is used in whole bowel irrigation?
Golytely
31
What chelator is used for arsenic, mercury, lead, and cadmium poisoning?
Dimercaprol (BAL)
32
What chelator is used for copper, lead, mercury, arsenic toxicity?
Penicillamine
33
What chelator is used for iron toxicity?
Deferoxamine
34
What chelator is used for lead, arsenic, and mercury poisoning?
DMSA (Succimer)
35
What chelator is used for lead toxicity?
Edetate Calcium Disodium (EDTA)
36
What antivenin is used for rattlesnake envenomation?
crotalidae antivenin
37
What biologics is used for botulism A, B, and E?
Trivalent botulism
38
What antivenin is used for eastern and Texas coral snake envenomation?
Elapidae Antivenin
39
What biologic is used for Digoxin and Digitoxin?
Digoxin Immune Fab
40
What antivenin is used for black widow spider envenomation?
Lactrodectus Antivenin
41
What is the antidote to organosphosphate and pesticide poisoning?
atropine
42
What is the antidote to methanol and ethylene glycol toxicity?
Fomepizole
43
What is the antidote to opiods?
Naloxone
44
What is the antidote to acetaminophen toxicity?
N-acetylcysteine
45
What is the antidote to benzodiazepine toxicity?
Flumazenil

Drugs Pharm Quarter 3 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions