Histiocytosis

Question 1

Write short notes on the pathogenesis of Langerhans cell histiocytosis

Answer 1

Question 2

Write short notes on the types of Langerhans cell histiocytosis
-age of onset
-clinical presentation
-other high yield facts

Answer 2

Question 3

Name the main groups of non langerhans cell histiocytosis

Answer 3

1. Primarily cutaneous (self resolving)
   - Juvenile xanthogranuloma
   -Benign cephalic Histiocytosis (likely JXG variant)
   - Generalized eruptive histiocytosis (likely a JXG variant)
   - Intermediate cell histiocytosis (ICH)
2. Cutanoeus (with frequent systemic involvement)
   -Necrobiotic xanthogranuloma
   - Reticulohistiocytosis (Solitary reticulohistiocytosis and
   (Multicentric Reticulohistiocytosis
   - Rosai Dorfman
   - Xanthoma Disseminatum
3. Systemic, usually without skin involvement
   - Erdheim-Chester

Question 4

Write short notes on Juvenile xanthogranuloma
-age of onset
-clinical presentation
-other high yield facts

Answer 4

Question 5

Write short notes on benign cephalic histiocytosis

Answer 5

Question 6

Write short notes on Generalized eruptive histiocytosis

Answer 6

Question 7

Write short notes on Intermediate cell histiocytosis

Answer 7

Question 8

Write short notes on Reticulohistiocytosis

Answer 8

Question 9

Write short notes on Rosai dorfman

Answer 9

Question 10

Write short notes on canthoma disseminatum

Answer 10

Question 11

Write short notes on Erdheim-Chester

Answer 11

Question 12

Picture of langerhans cell histiocytosis

Answer 12

Question 13

Write notes on juvenile xanthogranuloma

Answer 13

Question 14

Picture of benign cephalic histiocytosis

Answer 14

Question 15

Picture of xanthoma disseminatum

Answer 15

Question 16

Picture of multicentric reticulohistiocytosis

Answer 16

Question 17

Monoclonal gammopathies in dermatology

Answer 17

Question 18

Write notes on histiocytosis

Answer 18

Question 19

2 patterns of associations between LCH + maligancy

Answer 19

Question 20

Pathology of LCH

Answer 20

Question 21

Pathology of LCH

Answer 21

Question 22

Diff dx of LCH

Answer 22

Question 23

Treatment of Langerhans cell histiocytosis

Answer 23

Question 24

Clinical features of intermediate cell histiocytosis

Answer 24

Question 25

Clinical features of Juvenile Xanthogranuloma

Answer 25

Question 26

Treatment of JXG

Answer 26

Question 27

Clinical features of the histiocytosis (Bolognia table 1)

Answer 27

Question 28

Clinical features of histiocytosis (Bolognia table 2)

Answer 28

Question 29

Pictures of LCH

Answer 29

Question 30

Stain of LHC

Answer 30

Question 31

Picture of congenital self healing reticulohistiocytosis (Hashimoti-Pritzker)

Answer 31

Question 32

Antigenic markers of the histiocytosis (bolognia table)

Answer 32

Question 33

Immunohistochemistry lf the histiocytosis

Answer 33

Question 34

Picture of elecronsmictoscopy

Answer 34

Question 35

Use if a panel of immunostains to distinguish between several types of histiocytosis

Answer 35

Question 36

Picture of benign cephalic histiocytosis

Answer 36

Question 37

Picture of generalized eruptive histiocytoma

Answer 37

Question 38

Picture of benign cephalic histiocytosis

Answer 38

Question 39

Picture of Juvenile xanthogranuloma

Answer 39

Question 40

Picture of necrobiotic xanthogranuloma

Answer 40

Question 41

Picture of multicentric histiocytosis

Answer 41

Question 42

picture of Rosai Dorfman

Answer 42

Question 43

Picture of Xanthoma disseminatum

Answer 43

Question 44

Table of clinical and immunophenotypical features of the malignant histiocytic diorders

Answer 44

Question 45

Pictures of xanthoma disseminatum

Answer 45

Question 46

Dermal dendrocyte hamartomas

Answer 46