Histo 1 Connective Tissues Fibrous

Question 1

What is Marfan’s syndrome?

Answer 1

• Autosomal dominant disorder where elastin is weak
• occular, skeletal, and cardiovas sytems
• life threatening (from cardiovas)
• tall long arms/legs

Question 2

Adipose CT characteristic and locations?

Answer 2

Question 3

functions of Connective tissues?

Answer 3

Question 4

Structure?

Answer 4

Fibroblast

Question 5

Dense regular CT function?

Answer 5

Question 6

Fibroblast function

Answer 6

Question 7

Fixed cells vs wandering cells

Answer 7

Question 8

Dense irregular function and location?

Answer 8

Question 9

What are CT cells separted by?

Answer 9

Extracellular matrix.

Question 10

extracellular proenzyme

Answer 10

amorphous ground substance

needs to be activated

Question 11

Proteoglycans

Answer 11

Question 12

Embryonic Connective tissue

Answer 12

• Rich in ECM (more ECM than cells)
• Rich in Mesenchymal stem cells
• some collagen or reticular fibers (not many)
• in umbilical cord (wartons jelly)

Question 13

what causes Marfan’s syndrome?

Answer 13

mutation in fibrillin-I gene (component of elastin fibers)

Question 14

Plasma cells

Answer 14

differentiate from B- lymphocytes

produce antibodies that mediate immunity

Question 15

The different fibrous components of ECM of connective tissues

Answer 15

Question 16

Is connective tissue normally exposed to the outside environment?

Answer 16

No, it is normally separated by epithelium

Question 17

What are the types of fibrous connective tissue classes?

Answer 17

Loose connective tissue

and

dense connective tissue

Question 18

Scurvy and CT

Answer 18

vitamin C deficiency leads to

deficiency in co-factor in cross-linking collagen fibers

Weakens CT

Question 19

what does ECM carry?

Answer 19

oxygen, CO2, nutrients, and wastes

Question 20

glycoproteins

Answer 20

Question 21

elastic CT

Answer 21

Question 22

White vs brown fat?

Answer 22

Question 23

ECM amorphous ground substance types?

Answer 23

• Proteoglycans
• hyaluronan
• glycoproteins
• extracellular proenzymes

Question 24

tissue?

Answer 24

dense regular CT

Question 25

Hyaluronan

Answer 25

(hyaluronic acid)

Question 26

Types of CT cells? (examples)

Answer 26

Question 27

Type of CT?

Answer 27

Loose Areolar CT

Question 28

Type-1 collagen fibers?

Answer 28

* aligned and crosslinked to increase tensile strength * Banding observed (fibril alignment) * 2 alpha type 1 and a alpha type 2

Question 29

Adult Mesenchymal Stem cells

Answer 29

are multipotent stem cells that differentiate into: * fibroblasts * muscle cells (smooth/skeletal) * osteoblasts * chondroblasts * adipocytes

Question 30

What is this tissue?

Answer 30

Reticular Connective Tissue

Question 31

Macrophages?

Answer 31

differentiate from blood monocyte phagocytosis and destruction of * bacteria * damaged or sick cells * cell debris antigen processing and presentation

Question 32

Tissue?

Answer 32

Elastic CT

Question 33

Types of loose connective tissue?

Answer 33

Question 34

Different major groups of CT?

Answer 34

* Embryonic CT * Adult CT * fibrous CT * loose (Areolar CT) * Dense regular * dense irregular * special: adipose, cartliage, bone, hematopoeitic

Question 35

Loose connective tissue function and location?

Answer 35

Question 36

What is this?

Answer 36

adipose tissue | (i believe white and brown)

Question 37

Types of Dense connective tissue?

Answer 37

Question 38

What is reticular connective tissue function and location?

Answer 38

Question 39

Look up structure difference of Mast Cells plasma cells Macrophages

Question 40

Mast cells

Answer 40

secrete chemicals such as histamine that mediate the allergic response and heparin (anti-coagulant of blood) resembe baso/eosinophils

Question 41

Ehlers-Danlos Syndrome

Answer 41

abnormal collagen synthesis leads to weak collagen fibers (multiple forms). (mutation in the enzymes that make collagen)

Question 42

What is ground substance?

Answer 42

extracellular matrix- gel like substance embedded with protein fibers (can be hard and mineralized in bone)

Question 43

Tissue?

Answer 43

Dense irregular connective tissue