Histology surface epithelium

Question 1

protein of zona occludens that maintains barrier between adjacent cells and apical and lateral domains

Answer 1

Occludin

Question 2

forms the backbone of each zonula occludens strand

forms the extracellular aqueous channels for paracellular passage of ions

Answer 2

claudins

Question 3

formation of occluding junctions in endothelial cells betwwen endothelial cells amd monocytes
zipper and seal functions
barrier against paracellular diffusion

Answer 3

Junctional adhesion molecule (JAM)

Question 4

pathway of substance transport that requires energy

across the plasma membrane of the epithelial cells

Answer 4

Transcellular pathway

Question 5

across zonula occludens between two adjacent cells

Answer 5

paracellular pathway

Question 6

The permeabilityy of occluding junction depends on:

Answer 6

molecular composition of aonula occludens strands
number of active aqueous channels
claudins

Question 7

responsible for the formation of extracellular aqueuous channel

Answer 7

claudins

Question 8

mechanical stability for epithelial cells
found on lateral cwll surface and basal domain of epithelial cells
structural unity
with signal transduction
cell to cell recognition
interacts with intrmediate filaments

Answer 8

Adhering or anchoring junction, zona adherens

Question 9

part of every anchoring junction on. oth kayeral and basal cell surfaces

Answer 9

cell adhesion molecules (CAM)

Question 10

allows cells to easily join and dissociate

Answer 10

selective adhesiveness

Question 11

linked through a variety of intravellular proteins to components of cell cytoskeleton

Answer 11

cytoplasmic domains

Question 12

transmembrane Ca+ dependent CAMS

regulate mechanisms of growth snd cell differentiation

Answer 12

Cadherins

Question 13

interact with extracellular matrix molecules and with actin filaments of cytoskeleton
controls cell movement and shape

Answer 13

integrins

Question 14

expressed on WBC wnd endothelial cells
mediate neutrophil-endothelial cell recognition
involved in directing lymphocytes

Answer 14

selectins

Question 15

mediate homotypic cell to cell adhesion

Answer 15

Ig superfamily (IgSF)

Question 16

for epithelial surface integrity
continuous band belt-like configuration
witn E cadherin

Answer 16

zonula adherens

Question 17

anchoring crll to cell junction that provides a strong attchement

Answer 17

macula adherens (desmosome)

Question 18

cytoplasmic bundles containing bundle

Answer 18

cillia

Question 19

inter al structure found in the hair.ike extensionsof the apical plasma membrane

Answer 19

axoneme microtubule based

Question 20

where axoneme. extends from centriole-derived microtubule

Answer 20

basal body

Question 21

what are the classification of cillia?

Answer 21

motile
primary
nodal

Question 22

numerous on the apical domain of many epithelial cells
with flagella to transports
erm
has 9+2 axonemal organization

Answer 22

motile cillia

Question 23

solitary prijections found on eukaryotic cells
monocilia-single cilium per cell
immotile
chemosensors, light sensors, sound perception

Answer 23

primary ciliia (monocilia)

Question 24

found in bilaminarembryonicdisc of the embryo(gastrulation)
surroundsprimitive node
performs rotational movement
for early embryonic development

Answer 24

nodal cillia

Question 25

short, fine, hair-like structures

Answer 25

motil cilia

Question 26

thin darkstaining band extending across the cell at the base of the cilia

Answer 26

basal bodies

Question 27

from the tip of the cilium to its base

Answer 27

9+2 microtubule array

Question 28

collar like extension between the transitional zone of basal body and plasma membrane

Answer 28

alar sheet (transitionak fiber)

Question 29

found in the midregion of thbasal body for ciliary movement coordination adjusting the badal bodies by rotating them

Answer 29

basal foot

Question 30

made of rootletin-containing protofilaments | projects and anchors the basal body within the apical cell cytoplasm

Answer 30

striated rootlet

Question 31

based on the movement of th doublet microtubules

Answer 31

ciliary activity

Question 32

initiated by dynein arms | exhibits rapid forward movement

Answer 32

ciliary activity

Question 33

cilia becomes flexible | slower return movement

Answer 33

recovery stroke

Question 34

moving mucus over epithelial surfaces | flow of fluid and other substances through tubular organs and ducts

Answer 34

cilia metachronal rhythm

Question 35

only one cilium found on rete testis ependymal cells cavities of CNS

Answer 35

primary cells

Question 36

cytoplasmic processes containing a core of actin filaments

Answer 36

microvili

Question 37

unusually long, immotile microvilli that extends from apical surfaces found on epididymis ductis deferens sensory hair

Answer 37

stereocilia

Question 38

unusually long motile microvilli resembles the hairs of a paint brush supported by internal bundles of actin filaments cross-linked by fimbrin

Answer 38

streovilli

Question 39

impermeable allow epithelial cells to function as a barrier for primary intercellular diffusion barrier prevent migration of lipids

Answer 39

Zona occludens

Question 40

Interface between dupport tissues and parencyma

Answer 40

Compartmentalization

Question 41

initiates development of basal lamina

Answer 41

Laminins

Question 42

Used to identify the basement membrane

Answer 42

Periodic acid schiff (PAS)

Question 43

main layer of basal lamina

Answer 43

Lamina densa

Question 44

major component of the basal lamina proteins

Answer 44

type IV collagen

Question 45

anchoring fibrils that link basal lamina to reticular lamina

Answer 45

Type VII

Question 46

stabilizing lamina in skeletal and cardiac muscle

Answer 46

Type XV

Question 47

in vascular and epithelial basal laminae for angiogenesis

Answer 47

Type XVII

Question 48

involved in he cell to extracellular matrix interactions for basal lamina assembly for development differentiation and remodeling of epithlium

Answer 48

laminins

Question 49

link between laminin and the type IV collagen network bind Ca+ support cell adhesion promote neutrophil chemotaxis and phgocytosis

Answer 49

Entactin/Nidogen

Question 50

pathway in between cells

Answer 50

paracellular pathway

Question 51

pathway through cells

Answer 51

transcellular pathway

Question 52

hearing receptors | mechanoreceptors

Answer 52

streocilia

Question 53

type of cilia that can move separately | passive

Answer 53

micorvilli

Question 54

has cytoplasmic ridges | moves dependently

Answer 54

streocillia

Question 55

seen on skin, cornea

Answer 55

ectoderm

Question 56

seen in alimentary tract, liver and pancreas

Answer 56

endoderm

Question 57

seen in kidneys, reproductive tissues, endothelium and mesothelium

Answer 57

mesoderm

Question 58

between basal lamina and th cell | clear tand electron lucent area

Answer 58

Lamina lucida

Question 59

layers composed of cells covering the extertior body surfaces

Answer 59

basal lamina

Question 60

an arifact, not a true layer

Answer 60

lamina lucida

Question 61

numerous on th apical domain of many epithelial cells | posses 9+2 axonemal organizAtion

Answer 61

motile cilia

Question 62

solitary projections found on eukaryotic cells connecting stalks of photorceptor cells ependymal cells lining fluid-filled cavities pf CNS

Answer 62

primary cilia (monocilia)

Question 63

``` found in bilaminar embryonic disc pf the embryo gastrulation surrounds primitive node perform rotational movement for early embryonic develoment ```

Answer 63

nodal cilia

Question 64

cilia + basal bodies

Answer 64

ciliary apparatus

Question 65

site of microfilAment is in the?

Answer 65

Zona adherens

Question 66

maintain the morphologic integrity of the epithelium-connective tissue interface

Answer 66

anchoring junctions

Question 67

anchor actin filaments of th cytoskeleton into the basement membrane

Answer 67

focal adhesio s

Question 68

anchor intermediate filaments of th cytoskeleton into the basement membrane

Answer 68

hemidesmosomes

Question 69

amino acid sequence of the cytoplasmic portions of all three proteins

Answer 69

PDZ-domain proteins