Histopathology and cytopathology

Question 1

4 histopatholgy samples

Answer 1

Biopsies
Resection specimens
Frozen sections
Post-mortems

Question 2

2 cytopathology samples

Answer 2

Smears

Fine needle aspirates

Question 3

3 things looked for in biopsy

Answer 3

Is it normal?
Is it inflamed- what is cause?
Is it cancer- what type?

Question 4

2 things looked for in resection specimen

Answer 4

How far has cancer spread

Is it all out

Question 5

Great thing about frozen section

Answer 5

Very rapid diagnosis

Question 6

Things looked for in frozen section

Answer 6

Is it cancer?
Is it all out?
Is there something else going on?

Question 7

2 types of post mortem

Answer 7

Hospital- where family gives permission if medics request it

Coroners- post mortem where cause of death legally constitutes a post morterm

Question 8

What is done with tissue section once obtained

Answer 8

Must be labelled properly
Fixd in formalin
Embedded in paraffin wax
Cut into sections

Question 9

What is done with sections in lab

Answer 9

Certain stains- Gram eg
Immunohistochemistry
Molecular tests

Question 10

What is immunohistochemistry

Answer 10

Using antibodies to identify antigens in a sample

Question 11

Time difference in results to get reach clinician frozen section, biopsies and resection specimens

Answer 11

30 mins
2-3 days
5-7 days