History

Question 1

worked on serum therapy

Answer 1

Emil Adolf von Behring

Question 2

known for his work on malaria, where he discovered the life cycle of Plasmodium in mosquito.

Answer 2

Ronald Ross

Question 3

founder of modern bacteriology

known for his role in identifying the specific causative agents of tuberculosis, cholera, and anthrax

Answer 3

Robert Koch

Question 4

 discovered pathogenic agent for malaria

Answer 4

1. Charles Louis Alphonse Laveran

Question 5

 Received the Nobel prize in recognition of his work on vascular suture and the transplantation of blood vessels and organs

Answer 5

1. Alexis Carrel

Question 6

 Studied, coined and treated “anaphylaxis”

Answer 6

1. Charles Robert Richet

Question 7

 led to an increased understanding of how the immune system affects the chances of getting cancer

Answer 7

1. Leonell Strong & Clarence Little

Question 8

 Discovery of Hapten (smallest antigen)

Answer 8

1. Karl Landsteiner

Question 9

for his discoveries relating to immunity (Complement)

Answer 9

1. JULES BORDET

Question 10

with Octave Gengou, he isolated Bordetella pertussis in pure culture in 1906 and posited it as the cause of whooping cough.

Answer 10

1. JULES BORDET

Question 11

For work on cutaneous allergic reactions

Answer 11

1. CARL PRAUSNITZ (AND HEINZ KÜSTNER

Question 12

Found lysosome

Answer 12

1. ALEXANDER FLEMING

Question 13

He cured syphilis with malaria therapy.

Answer 13

1. Julius Wagner-Jauregg

Question 14

the first to test the efficacy of transfusing humans with cadaver blood.

Answer 14

2. Dr. Serge Yudin

Question 15

He demonstrated that the specific arrangement between antigen, antibody, and complement is accompanied by the manufacture of anaphylatoxin

Answer 15

1. Ernst Friedberger

Question 16

 Production of the anti-diphtheria serum

Answer 16

Pierre Paul Emile Roux

Question 17

 Discovered the antigen-antibody hypothesis

Answer 17

John MArrack

Question 18

 Quantitative precipitin reaction

Answer 18

Michael Heidelberger

Question 19

the first major histocompatibility complex discovered.

Answer 19

histocompatibility-2 (H-2)

Question 20

 Identification of the H-2 antigen in mice

Answer 20

Peter Gorer

Question 21

the world’s foremost authority on the serology and serological genetics of tissue transplantation.

Answer 21

Peter Gorer

Question 22

 Identification of Rh antigens

Answer 22

Karl Landsteiner / Alexander Weiner

Question 23

 Developed the immunofluorescent technique

Answer 23

1. Albert Coons

Question 24

 Immunological hypothesis of allograft rejection

Answer 24

1. Peter Medwar

Question 25

 Establish theorems of transplantation immunity

Answer 25

1. Peter Medwar

Question 26

 helped develop a Japanese encephalitis vaccine to protect American troops in the World War II Pacific theater of operations

Answer 26

1. Maurice Hilleman

Question 27

antibody production in relation to the development of plasma cells.

Answer 27

1. Astrid Fagraeus

Question 28

genetically determined structures on the cell surface that regulate immunological reactions

Answer 28

1. George Davis Snell

Question 29

discovered the suppressor T cells

Answer 29

1. Richard Gershon

Question 30

 Published Yellow Fever in 1951

Answer 30

1. Max Theiler

Question 31

 He is also known as "The Father of Modern Vaccines"

Answer 31

1. John Franklin Enders

Question 32

 Discovery in 1937 of antihistamines which block the neurotransmitter histamine and are used

Answer 32

1. Sir Daniel Bovet

Question 33

his discovery relating to synthetic compounds for the blocking of the effects of certain substances occurring in the body, especially in its blood vessels and skeletal muscles

Answer 33

Sir Daniel Bovet

Question 34

 Discovery of acquired immunological tolerance.

Answer 34

1. Sir Frank McFarlane

Question 35

discovered that Major Histocompatibility Complex (MHC) is also responsible for antigen recognition of T cells from the infected cells aside from the virus antigen

Answer 35

1. PETER C. DOHERTY and 2. Rolf Martin Zinkernagel

Question 36

demonstrated the relationship between hormones and certain types of cancer

Answer 36

3. CHARLES HUGGINS

Question 37

Discovered a virus that can cause cancer in chickens

Answer 37

4. FRANCIS PEYTON ROUS

Question 38

Interpretation of the genetic code and its function in protein synthesis.

Answer 38

1. Robert W. Holley, Har Gobind Khorana and Marshall w. Nirenberg

Question 39

 Discoveries concerning the replication mechanism and the genetic structure of viruses

Answer 39

1. Max Delbrück, Alfred D. Hershey and Salvador E. Luria

Question 40

 Discovery on the interaction between tumor viruses and the genetic material of the cell

Answer 40

David Baltimore and 2. Renato Dulbecco and 1. Howard Martin Temin

Question 41

Hepatitis B virus, and later developed its diagnostic test and vaccine.

Answer 41

Baruch Samuel Blumberg

Question 42

Developed radioimmunossay (RIA) techniques; used RIA to analyze peptide hormones in the brain

Answer 42

Rosalyn S. Yalow/Roger C.L. Guillemin/ Andrew Schally

Question 43

restriction enzymes and their application to problems of molecular genetics

Answer 43

Werner Arber/ Daniel Nathans/ Hamilton Smith

Question 44

biochemistry of recombinant DNA

Answer 44

2. Paul Berg

Question 45

sequencing of DNA

Answer 45

3. Walter Gilbert and Frederick Sanger

Question 46

 discoveries concerning prostaglandins and related biologically active substances

Answer 46

1. Sune K. / John Vane / Bengt Ingemar Samuelsson

Question 47

mobile genetic elements

Answer 47

1. Barbara McClintock

Question 48

PCR

Answer 48

2. Kary Mullis

Question 49

concerning the specificity in development (lymphocyte clonality

Answer 49

1. Niels Jerne

Question 50

production of monoclonal antibodies

Answer 50

2. Cesar Milstein/ Georges Koehler

Question 51

the genetic mechanism that produces antibody diversity

Answer 51

1. Susumu Tonegawa (利根川 進 Tonegawa Susumu)

Question 52

discovery of the cellular origin of retroviral oncogenes.

Answer 52

1. Harold Vermus and J. Micheal Bishop

Question 53

"organ and cell transplantation in the treatment of human disease."

Answer 53

1. J.E. Murray and E.D. Thomas

Question 54

how the immune system recognizes virus-infected cells uncovered the general mechanisms of the immune system to distinguish foreign agents from its own cells and tissues

Answer 54

1. ROLF M. ZINKERNAGEL and PAUL C. DOHERTY

Question 55

 specificity of the cell mediated immune defense ("dual recognition").

Answer 55

1. ROLF M. ZINKERNAGEL and PAUL C. DOHERTY

Question 56

 for their discovery of human immunodeficiency virus

Answer 56

1. Françoise Barré-Sinoussi and Luc Montagnier

Question 57

 discoveries concerning the activation of innate immunity

Answer 57

1. B.A. Beutler and J.A. Hoffmann

Question 58

 discovery of the dendritic cell and its role in adaptive immunity

Answer 58

2. R. M. Steinman