History

Question 1

Father of Immunology

Answer 1

Louis Pasteur

Question 2

Introduced HIV

Answer 2

Montagner and Sinoussi

Question 3

1st blood transfused

Answer 3

Pope Innocent VII

Question 4

T cell receptor gene discovery (year)

Answer 4

1984

Question 5

Bacteria with No cell wall

Answer 5

Mycoplasma & Ureaplasma

Question 6

Phagocytosis

Answer 6

Initiation (CR3)
Chemotaxis (C5a)
Engulfment (C3b)
Digestion (Ureaplasma)

Question 7

Test for Chemotaxis

Answer 7

Boyden Chamber Assay

Question 8

Cachectin by Macrophages

Answer 8

TNF-alpha

Question 9

Causes meningitis

Answer 9

H.influenzae
N.meningitidis
S.pneumoniae

Question 10

CGD

Answer 10

failure of Neutrophils to produce O2

(-) NADPH Oxidase

Question 11

CGD Test

Answer 11

NBT Dye test

Question 12

CGD blood component

Answer 12

Granulocyte concentration

Question 13

Complement activation

Answer 13

C142356789

Question 14

Receptor for EBV

Answer 14

CD21

Question 15

Have IgD on surface

Answer 15

Mature B cells

Question 16

Discovered 1st in Bursa of Fabricius in Birds

Answer 16

B cell

Question 17

Identified by E-Rosette

Answer 17

T cell

Question 18

HLA can be found on

Answer 18

Chromosome 6 (short arm)

Question 19

Most efficient APR

Answer 19

Dendritic cells

Question 20

A potent antigen has a weight of

Answer 20

> 10 kDa

Question 21

Most immynogenic graft

Answer 21

BM

Question 22

Least immunogenic graft

Answer 22

Cornea

Question 23

Most acceotable theory

Answer 23

Clonal selection theory

Question 24

Best to cross placenta

Answer 24

IgG1

Question 25

Don't cross the placenta

Answer 25

IgG2

Question 26

Best to fix complement

Answer 26

IgM

Question 27

IgM

Answer 27

Agglutination

Question 28

IgG

Answer 28

Precipitation

Question 29

Antigen-antibody complexes

Answer 29

Classical pathway

Question 30

Microorganism's mannose

Answer 30

Lectin pathway

Question 31

Most severe

Answer 31

C2 deficiency

Question 32

Most common deficiency

Answer 32

C2 deficiency

Question 33

Hutchinsonian triad can be found in

Answer 33

Congenital syphilis

Question 34

Hutchinsonian triad consists of

Answer 34

Keratitis Notched teeth Deafness

Question 35

Primary syphilis symptom

Answer 35

Hard chancre Dx: dark field

Question 36

Secondary syphilis

Answer 36

Condylomata lata Dx: Dark field, serologic test

Question 37

Latent stage

Answer 37

Asymptomatic Dx: serologic

Question 38

Tertiary syphilis

Answer 38

Gummas (found treponemes) Dx: serologic

Question 39

Serologic tests for Syphilis

Answer 39

Wasserman test : C' fixation Nontreponemal serologic: VDRL, RPR Treponemal serologic: TPI, FTA-ABS, TPHA, MHA-TP, HATTS)

Question 40

Gold standard syphilis test

Answer 40

FTA-ABS

Question 41

ASO is reported in what units

Answer 41

Todd units NV: 0-166

Question 42

Dane particle

Answer 42

Hepatatis B

Question 43

Major cause of post transfusion Hepatitis

Answer 43

Heoatitis C

Question 44

Coinfection hepatitis

Answer 44

Hepatitis D with Hepa B

Question 45

Australia antigen

Answer 45

HBsAg 1st marker to appear

Question 46

High vertical transmission

Answer 46

HBeAg

Question 47

NOT a serologic marker

Answer 47

HBcAg

Question 48

1st Antibidy produced

Answer 48

IgM anti-HBc

Question 49

Total anti-HBc

Answer 49

Lifelong marker

Question 50

Core window

Answer 50

IgM anti-HBc

Question 51

Lifelong marker hepatitis

Answer 51

Total anti-HBc

Question 52

Convalescence marker

Answer 52

Anti-HBc

Question 53

HBsAg test

Answer 53

``` 1st gen. Test: ouchterlony double diffusion 2nd gen test: counterelectrophoresis Rheophoresis C' fixation 3rd gen test: RIA, ELISA, RPHA, RPKA ```

Question 54

HIV envelope gene

Answer 54

gp160, gp120, gp41

Question 55

Gag genes

Answer 55

p55, p15, p17, p24

Question 56

First antibody to appear in HIV infection

Answer 56

p24

Question 57

HIV Screening

Answer 57

ELISA (standard) Agglutination Dot-Blot

Question 58

HIV Confirmatory

Answer 58

``` Western blot (gold standard) Immunofluorescence assay ```

Question 59

RA Tests

Answer 59

Rose-Waaler test (sheep cell) | Singer-plotz test (latex fixation)

Question 60

Infectious mononucleosis

Answer 60

EBV

Question 61

Test for IM

Answer 61

Paul-Bunnell Screening test | Davidson differential test

Question 62

Forssman antigen

Answer 62

Infectious mononucleosis

Question 63

Widal test is for

Answer 63

S. Typhi

Question 64

Weil-Felix test

Answer 64

Rickettsii

Question 65

Cook who became famous because of carrier of febrile disease who killed 50% persons

Answer 65

Mary Mallon