History Flashcards
(30 cards)
430 BC
Thucydides (Athens) “immune”
1000 AD
inhaling dried powders from smallpox lesions
1700’s
milk maids were immune to smallpox because of their contraction of cowpox
1798
Edward Jenner
smallpox vaccine
1862
Haeckel
Phagocytosis
1880-1881
Louis Pasteus
cholera and anthrax vaccine; germ theory
1882-1905
Metchnikoff
cellular immunity through phagocytosis
1885
Pasteur’s vaccine for rabies
1890
Von Behring, Kitasata’s
humoral theory of immunity
1891
Koch’s
demonstration of cutaneous hypersensitivity
1900
Ehrlich’s
antibody formation theory
1902
Portier and Richet’s
immediate-hypersensitivity anaphylaxis
1903
Arthus
reaction of intermediate hypersensitivity
1938
Marrack’s
hypothesis of antigen-antibody binding
1944
Allograft rejection hypothesis
1949
Salk and Sabin’s
polio vaccine
1951
Reed’s
vaccine for yellow fever
1956
graft-vs-host reaction
1957
Burnet’s
clonal selection theory
1957
Interferon
1958
Human leukocyte antigens (HLAs)
1964-1968
T-cell and B-cell cooperation in immune response
1972
Antibody molecule
1975
Kohler’s
first monoclonal antibodies