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Flashcards in History Deck (30)
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1

430 BC

Thucydides (Athens) "immune"

2

1000 AD

inhaling dried powders from smallpox lesions

3

1700’s

milk maids were immune to smallpox because of their contraction of cowpox

4

1798

Edward Jenner
smallpox vaccine

5

1862

Haeckel
Phagocytosis

6

1880-1881

Louis Pasteus
cholera and anthrax vaccine; germ theory

7

1882-1905

Metchnikoff
cellular immunity through phagocytosis

8

1885

Pasteur’s vaccine for rabies

9

1890

Von Behring, Kitasata’s
humoral theory of immunity

10

1891

Koch’s
demonstration of cutaneous hypersensitivity

11

1900

Ehrlich’s
antibody formation theory

12

1902

Portier and Richet’s
immediate-hypersensitivity anaphylaxis

13

1903

Arthus
reaction of intermediate hypersensitivity

14

1938

Marrack’s
hypothesis of antigen-antibody binding

15

1944

Allograft rejection hypothesis

16

1949

Salk and Sabin’s
polio vaccine

17

1951

Reed’s
vaccine for yellow fever

18

1956

graft-vs-host reaction

19

1957

Burnet’s
clonal selection theory

20

1957

Interferon

21

1958

Human leukocyte antigens (HLAs)

22

1964-1968

T-cell and B-cell cooperation in immune response

23

1972

Antibody molecule

24

1975

Kohler’s
first monoclonal antibodies

25

1985-1987

Genes for T cell receptor

26

1986

Monoclonal Hepatitis B vaccine

27

1986

Mosmann’s
Th1 vs Th2 model of helper cell function

28

1996-1998

Identification of toll-like receptors

29

2001

FOXP3, the gene directing regulatory of human T cell development

30

2005

Frazer’s
HPV vaccine