HIV Drug Dosing

Question 1

Abacavir

Answer 1

600mg daily or 300mg BID

Question 2

Didanosine

Answer 2

400mg daily or 250mg daily (<60kg)

Question 3

Emtricitabine

Answer 3

200mg daily (240mg oral solution)

Question 4

Lamivudine

Answer 4

300mg daily or 150mg BID

Question 5

Stavudine

Answer 5

40mg BID or 30mg BID (<60kg)

Question 6

Tenofovir disoproxil fumarate

Answer 6

300mg daily

Question 7

Tenofovir alafenamide

Answer 7

25mg daily (10mg daily if boosted)

Question 8

Zidovudine

Answer 8

300mg BID or 200mg TID (alternative)

Question 9

Delavirdine

Answer 9

400mg TID

Question 10

Efavirenz

Answer 10

600mg qHS

Question 11

Nevirapine

Answer 11

200mg BID or 400mg daily (titrate 200mg daily for 14 days then 200mg BID or 400mg daily d/t rash)

Question 12

Etravirine

Answer 12

200mg BID with food

Question 13

Rilpivirine

Answer 13

25mg daily with full meal

Question 14

Atazanavir

Answer 14

300mg daily (with ritonavir 100mg daily)
400mg daily (alternative, naive only)
taken with food, needs high pH

Question 15

Darunavir

Answer 15

800mg daily (with ritonavir 100mg daily - naive)
600mg BID (with ritonavir 100mg BID if DRV mutation)

Question 16

Fosamprenavir

Answer 16

700mg BID (with ritonavir 100mg BID)
1400mg BID (naive only)
1400mg daily (with ritonavir 100-200mg daily - naive only)

Question 17

Indinavir

Answer 17

800mg q8h
800mg BID (with ritonavir 100-200mg BID)

Question 18

Lopinavir/ritonavir

Answer 18

400/100mg BID

800mg/200mg daily (<3 LPV mutations)

Question 19

Nelfinavir

Answer 19

1250mg BID

750mg TID

Question 20

Ritonavir

Answer 20

100-400mg 
600mg BID (boosting - titrate 300mg BID days 1-2, 400mg BID days 3-5, 500mg BID days 6-13)

Question 21

Saquinavir

Answer 21

1000mg BID (with ritonavir 100mg BID)

Question 22

Tipranavir

Answer 22

500mg BID (with ritonavir 200mg BID)

Question 23

Raltegravir

Answer 23

400mg BID (only 1st line that requires BID)

Question 24

Elvitegravir

Answer 24

85mg daily (with ATV/r, LPV/r)
150mg daily (with DRV/r, AMP/r, TPV/r, cobicistat)

Question 25

Dolutegravir

Answer 25

``` 50mg daily (INSTI-naive) 50mg BID (INSTI-experienced) ```

Question 26

Maraviroc

Answer 26

``` 300mg BID 150mg BID (CYP3A4 inhibitors +/- inducers) 600mg BID (CYP3A4 inducers) ```

Question 27

Enfuvirtide

Answer 27

90mg (1mL) subcutaneous BID

Question 28

Cobicistat

Answer 28

150mg daily (boost)

Question 29

Atripla

Answer 29

EFV 600mg/FTC 200mg/TDF 300mg daily

Question 30

Complera

Answer 30

RPV 25mg/FTC 200mg/TDF 300mg daily

Question 31

Genvoya

Answer 31

EVG 150mg/COBI 150mg/FTC 200mg/TAF 10mg daily

Question 32

Odefsey

Answer 32

RPV 25mg/FTC 200mg/TAF 25mg daily

Question 33

Stribild

Answer 33

EVG 150mg/COBI 150mg/FTC 200mg/TDF 300mg daily

Question 34

Triumeq

Answer 34

ABC 600mg/DTG 50mg/3TC 300mg

Question 35

Truvada

Answer 35

FTC 200mg/TDF 300mg daily (also in 100/150 and 167/350)

Question 36

Descovy

Answer 36

FTC 200mg/TAF 25mg daily

Question 37

Epzicom

Answer 37

ABC 600mg/3TC 25mg daily

Question 38

Combivir

Answer 38

3TC 150mg/ZDV 300mg BID

Question 39

Trizivir

Answer 39

ABC 300mg/3TC 150mg/ZDV 300mg BID