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Flashcards in HLA associations Deck (7)
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1
Q

HLA B27

A

Ank spond

2
Q

HLA DR15/DR2

A

Goodpasture’s

3
Q

HLA DR3

A

Graves and SLE

4
Q

HLA DR3/DR4

A

T1DM

5
Q

HLA DR4

A

RA

6
Q

PTPN22

A

Tyrosine phosphatase expressed in lymphocytes, associated with development of RA, SLE and T1DM

7
Q

CTLA4

A

Receptor for CD80/CD86 expressed by T cells, transmits inhibitory signal to control T cell activation. Assoicated with SLE, T1DM and AI thyroid disease