Homeostasis Flashcards

(61 cards)

1
Q

Animal’s bodies respond to changes in what 2 things?

A

The external environment
and their own internal environment

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2
Q

Metabolic activity of cells

A

Require O2, nutrients, and salts
Produce metabolic wastes

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3
Q

Changes in the internal environment arise from what 5 things

A

O2 concentration
Temperature
pH
salinity
humidity

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4
Q

Homeostasis means

A

The tendency to remain internally stable in the face of external fluctuations

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5
Q

Animals exhibit what 3 types of homeostasis?
What 2 matter here?

A

Thermoregulation
Osmoregulation*
Excretion*

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6
Q

What does the graph show?

A

Shore crab can survive in a wider range of salinities
Spider crab can survive in a smaller range of salinities

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7
Q

Open ocean def’n
examples?
respiratory surfaces are what?

A

Marine, open ocean
Spider crab and jellyfish
Permeable to water and salt

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8
Q

Osmotic conformers

A

total salinity of body fluids = total salinity of seawater by concentration

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9
Q

Stenohaline

A

Inability to withstand significant osmotic changes with respect to salinity
(narrow, salt or sea)

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10
Q

Brackish water def’n
problem for the invertebrates?

What 2 solutions to overcome the problem

A

The next level from marine, where it is somewhat salty but not as much as the open ocean
Passive salt loss and water gain

Salt-secreting glands in gills actively transport salt from environment into body
Green gland removes excess water via active transport

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11
Q

What is a hyperosmotic regulator

A

Organisms with higher concentration of body fluid than the environment (i.e. saline)

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12
Q

Shore crabs are euryhaline. What does this mean?

A

They can exist in a wide range of salinities

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13
Q

Earliest fishes lived in…
Earliest bony fishes lived where…

A

Marine environments
Evidence supports freshwater environments

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14
Q

FW bony fishes evolved to become…

A

More dilute in body concentration

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15
Q

Freshwater fish problem
Gills

A

Salt is passively lost, water is passively gained
Gills exacerbate salt loss and water gain

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16
Q

FW fish solutions
3 solutions

A

Effective hyperosmotic regulators
Excess water pumped out by kidney, forming dilute urine
Special salt-absorbing cells move salt from water into the blood (actively transported)
Food eaten by fish contains salts

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17
Q

Marine bony fishes origin

A

Evolved from freshwater ancestors and re-invaded the sea

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18
Q

Salinity of bony fishes

A

180 mM

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19
Q

Brackish water invertebrate salinity

A

~550 mM, same as open ocean invertebrates

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20
Q

Marine bony fish problem
2 solutions

A

Water loss, salt gain

Drink seawater->
Absorb water and salt from intestine into bloodstream->
Salt is carried by blood to gills, where it is actively transported out of the body
kidney secretes a very concentrated urine

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21
Q

Major source of water loss in terrestrial animals
3 kinds

A

evaporation from respiratory surfaces/body surface
urine excretion
feces elimination

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22
Q

Water loss recoup of terrestrial animals
air, food, and what else?

A

Drinking water (if available)
Harvesting water vapor from air
Free water in food
Metabolic water (oxidation of stores carbs and fats produces water)

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23
Q

Terrestrial animal water loss minimization?

A

Concentrated urine
Dry feces
Convert Nitrogenous waste to urea or uric acid

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24
Q

Amino acids to energy creates what?

A

Nitrogenous wastes

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25
Ammonia What uses this form of nitrogenous waste? Qualities?
Aquatic animals Highly soluble, toxic, quickly flushed if enough water is available 500 mL water to 1g of nitrogen waste Fish are not concerned with water conservation mostly
26
Urea What uses this? Qualities?
Amphibians, mammals Fairly simple compound, relatively nontoxic, soluble 50 mL water to 1g of Nitrogen waste Requires energy to convert ammonia to urea (15% of energy gained by amino acids is spent doing this)
27
Ureotelic
Urea excreting in urine
28
Uric acid What uses this? Qualities?
Birds, insects, reptiles More complex than urea More energetically expensive to produce than urea highly insoluble in water <10 mL of water per 1 gram of Nitrogen wasteW
29
Why do birds use uric acid
Keeps body-weight low and conserves water
30
Many animals have excretory organs for urea and uric acid but why doesn't ammonia require one (some still have them even if they make ammonia)
Ammonia is a small enough molecule to diffuse out of the body via respiratory membranes or body surfaces
31
Label this
32
Pathway of filtrate through nephron
Bowman's capsule -> p conv tubule -> loop of henle -> distal conv tubule -> collecting duct -> renal pelvis -> ureter
33
Renal corpuscle
Glomerulus and bowman's capsule
34
Cortex vs Medulla
Cortex is outer, Medulla is inner
35
Urine is composed of
Water, Urea, Excess ions
36
Kidneys receive _ % cardiac output Kidneys filter _ liters of blood
20-25 200 liters of blood
37
Nephron blood supply
Aorta -> renal artery -> afferent arteriole -> glomerulus -> efferent arteriole -> renal vein -> inferior vena cava
38
4 steps of urine formation
Glomerular filtration tubular reabsorption tubular secretion water excretion/concentration of urine
39
Glomerular filtrations occurs because... ___ slits.... Produces... What kind of process is it?
Occurs due to hydrostatic pressure in the glomerulus Filtration slits allow water and small ions to leave Produces protein-free filtrate Non-selective (200L is formed daily)
40
Tubular reabsorption Reclamation? Primarily occurs where? to what? _% reabsorbed? what is reclaimed nearly entirely? Happens due to _ What does water do?
Reclamation of valuable materials from the filtrate to peritubular capillaries Primarily occurs in the prox conv tubule ~60% glucose, amino acids, vitamins Active transport (unique ion pumps gather ions) Water passively follows the osmotic gradient with active reabsorption of solutes
41
Tubular secretion Primarily occurs where? Materials end up where?
-Nephron secretes materials into the filtrate (reverse of tubular reabsorption) -Occurs in dist conv tubule -Active transport of hydrogen ions, potassium ions, and drugs In the urine
42
Water excretion/Conservation
Kidney closely regulates the solute concentration of the blood
43
When fluid intake is high/low?
high - dilute urine low - conc urine
44
Mammalian adaptation? descending/ascending permeability? Collecting duct permeability
Loop of henle Descending is permeable to water, not NaCl Ascending is permeable to salt, not NaCl Variably permeable to water depending on ADH; permeable to urea
45
Conc gradient of nephron
Cortex is low osmolarity Medulla gets extremely concentrated osmolarity as it gets lower towards the descending loop of henle
46
Two ways of concentrating urine
Increasing solute concentration Decreasing water concentration (decreasing solvent concentration)
47
Sodium moves out of the ascending loop via.... in the upper portion lower portion
upper portion, via active transport lower portion, via diffusion
48
What happens if water diffuses out of collecting duct What is fluid entering the collecting duct What does urea diffusing out of CD do
Urine becomes more concentrated Dilute Increases solute concentration of interstitial fluid
49
ADH
increases permeability of collecting ducts to water, causing water retention
50
Water gain for kangaroo rats, humans? Water loss?
Metabolic water vs. Drinking Evaporation (lungs and skin) vs. Urine
51
Why do marine fishes have a body fluid salinity that is so much lower than that of the surrounding environment?
They evolve from freshwater fishes, who have a body salinity of 180 mM
52
Where do nitrogenous wastes come from? Why is it important to rid of them?
Amino acid metabolism. It is important to get rid of nitrogenous wastes because buildup in the body can cause toxicity.
53
Describe osmoregulatory challenges of these 5 organisms, explain how they meet those challenges Spider crab in 200 mM water (op ocean invert) Blue crab (brackish water crab) in 200 mM water Modern freshwater bony fish in FW 5 mM Marine bony fish in normal seawater 550 mM Desert lizard on land
Spider crab dies because it is stenohaline Blue crab (550 mM in brackish) - (passive salt loss, water gain) Green glands move water out, Salt-secreting glands take salt in from the environment Modern freshwater bony fish - (passive salt loss, water gain) Dilute urine, Eating foods with salts, Salt-absorbing cells move salts in Marine bony fish - (passive salt gain, water loss) Drink seawater and retain the water while excreting the salt, Concentrated urine Desert lizard on land - (water loss to evaporation, urine excretion, feces excretion) - Absorb water vapor, concentrated uric acid, retain water well from metabolism
54
Terrestrial animals convert ammonia to urea or uric acid. Mammals primarily excrete nitrogenous wastes in the form of urea, whereas birds, reptiles, and terrestrials insects excrete most nitrogenous waste in the form of uric acid. Why do you support that there is a diversity of strategies? Why don't all animals convert nitrogenous wastes to uric acid?
Some animals can afford to spend more water and have a more soluble option in their excretion pathway rather than having a very insoluble uric acid that costs a lot of energy to generate. Also, birds need to be lightweight so they need to minimize water loss. Uric acid is a great way to minimize water loss, so if that is a survival characteristic, then it would be necessary; however, that is not always the case.
55
Define/Relate Homeostasis/ Osmoregulation Stenohaline/Osmoconformer Euryhaline, hyperosmotic regulator
Homeostasis - the tendency to remain stable internally in the face of external fluctuations Osmoregulation - the maintenance of constant osmotic pressure in the fluids of an organism by the control of water and salt concentrations Osmoregulation is a system of regulating salt and water balance that maintains homeostatic conditions, thus maintaining homeostasis. Stenohaline - Able to survive in a narrow range of salinities Osmoconformer - The ability to maintain an osmolarity internally that is in sync with the environment These are both describing the ability to survive in an environment which requires relative osmolarities to be a key factor in survival. One is an inability to regulate osmolarity to the point where it cannot survive big changes, whereas the other is describing the ability to conform its internal environment to mimic that of the external environment. Euryhaline - Euryhaline is the ability to survive a cross a wide range of salinities Hyperosmotic regulator - The ability to maintain a high internal osmolarity in a low osmolarity environment These are both describing the ability to survive in an environment which requires relative osmolarities to be a key factor in survival, and both of these characteristics are describing an ability to survive in waters where external environments are different relative to one's internal environment. For example, euryhaline could survive a significant change in its external environment and still survive since it can survive in a wide range of salinities. Hyperosmotic regulators work to survive in an external environment that is different from its own internal environment constantly.
56
Nearly 200 liters (50 gallons) of filtrate are formed each day by the average human’s kidneys, yet we urinate considerably less urine than that. How is the filtrate modified before it leaves the body as urine?
Filtrate is reabsorbed and concentrated with wastes in the nephron. In the proximal convoluted tubule, vital nutrients are reabsorbed along with a lot of water passively going down its concentration gradient with the actively transporting ions/molecules. Water is reabsorbed in the descending loop of Henle down its concentration gradient. Water is also reabsorbed in the collecting duct when ADH is present.
57
Describe the role of each of the following parts of the nephron: a. distal convoluted tubule b. loop of Henle c. proximal convoluted tubule d. glomerulus e. Bowman’s capsule
Distal convoluted tubule - tubular reabsorption - where 60% of filtrate is reabsorbed Loop of henle - Water is reabsorbed as well as NaCl Proximal convoluted tubule - tubular secretion occurs here where waste products are placed in the filtrate from the interstitial fluid (protein-free) Glomerulus - Where a big blood vessel meets a little blood vessel, causing hydrostatic pressure to shoot filtrate into the bowman's capsule Bowman's capsule - allows a place for filtrate to be collected, as it is being released from the glomerulus Together, the glomerulus and Bowman's capsule create the renal corpuscle
58
What is meant by tubular reabsorption? Why is this an important process?
Tubular reabsorption is the reabsorption of water, amino acids, and sugar from the filtrate, and it is done in the proximal convoluted tubule via active transport. This process is important because reclamation of important materials from the filtrate enables us to actively filter out waste products more effectively and not waste valuable nutrients.
59
What is meant by tubular secretion? Why is this an important process?
Tubular secretion is important because this is an opportunity for the filtrate to be concentrated with waste products from the body. Without this process, H+, K+, and drugs would not be incorporated in this step.
60
Why do some desert animals (such as the kangaroo rat) have such long loops of Henle?
Desert animals have longer loops of henle to limit the amount of water and salt that they lose, so its increased length allows the loop of henle to extend deeper into the medulla, where more water and salt can be pulled out of the filtrate.
61
Why does drinking too much alcohol result in dehydration? (Hint: think about the role of antidiuretic hormone here.)
Alcohol inhibits ADH, thus not allowing it to act on the collecting duct and make it permeable to water. As a result, water loss is more extreme while it is inhibited and dehydration is exacerbated.