homeostasis Flashcards

(34 cards)

1
Q

what is homeostasis

A

physiological control systems that maintain the internal environment within restricted limits in responce to extrenal change

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2
Q

why do endotherms(warm blooded) have greater range of tolerance

A

they have homeostatic controls to withstand more conditions

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3
Q

what are the advantages of intrinsic protein receptors

A

the hormone does not have to enter the cell

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4
Q

decribe the secondary messanger system for blood glucose regulation

A

adrenaline binds to intrinsic receptors in the plasma membrane
adenylate cyclase is activated
cyclic amp is formed by atp
protien kinase is activated
glycogen hydrolised to glucose

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5
Q

what is gluconeolysis

A

making new glucose from lipids and amino acids

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6
Q

what is glycogenolysis

A

splitting of glycogen

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7
Q

what is glycogenesis

A

making of glycogen

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8
Q

name the parts of the islets of langerhan and what they do

A

beta cells - secret insulin
alpha cells - secretes glucagon

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9
Q

describe what happens when there is a rise in glucose concentration

A

detection by beta cells in the islets of langerhans
insulin produced and secreted and travels in the blood to bind to receptors on target cell causing muscle and liver to take in glucose leads to glycogenesis
stops glycogenolysis and gluconeogenesis

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10
Q

short and long term concequences of low blood pressure

A

confused and fatigued because nerves cannot function lon term
short term water potential of cells increase

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11
Q

describe what happens when there is a fall in blood glucose concentration

A

detection by alpha cells which produce and secrete glucagon
it binds to receptor cell adrenaline cyclase is released making camp from atp which phosphorylises protien kinase converting glycogen to glucose

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12
Q

describe the actions of glucagon

A

active enzymes effect in liver hydrolysis of glycogen to glucose
synthesises glucose from amino acids and glycerol

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13
Q

describe the action of adrenaline

A

adenylate cyclase activated atp to camp
phosphorylation to activate protein kinase
glycogen to glucose

effects liver and muscles

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14
Q

type 1 diabetes

A

doesnt produce insulin

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15
Q

type 2 diabetes

A

resistant to your own insulin

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16
Q

what can diabetes cause

A

high blood pressure because more osmosis into plasma membrane

blindness
stroke
amputation

17
Q

how do oral medications help diabetes

A

reduces glucose absorption in the ileum
stop starch digesion by inhibiting
amalyase
reduced glycogenolysis
increases insulin production from beta cells

18
Q

5 molecules that move into glomerular filtrate

A

h2o , glucose , hormones , amino acids , o2

19
Q

what 5 things that prevents the movement of small molecules out of capillaries into filtrate

A

enothelium and basement membrane
epithelial cells and renal capsual
podocytes
hydrostatic pressure in fluid of renal capsual space
osmotic pressure of glomerous filtrate

20
Q

what % of water reabsorption happens in the proximal convoluted tube

A

85 % out the the total 99%

21
Q

adaptations of the epithelial cell for reabsorption

A

micro villi to increase surface area so more diffusion happens
mitrochondria produces atp in oxidative phosphorylation
sodium potatsium pump

22
Q

what is the structure and function of the ascending limb of the loop of henle

A

thicker wall
starts narrow and the widens
impermeable to water but permeabel to mineral ions

23
Q

what is the structure and function in the decending limb in the loop of henle

A

thinner wall
narrow
permeable to water

24
Q

explain counter current flow in the loop of henle

A

the ascending limb and decending limb flow in opposite directions to maintain conc gradient across the whole length of the loop

25
describe the distal convoluted tubule
final ajustments to water , salt to maintain pH of the blood they have microvilli and many mitrochondria reabsorbs by active transport hormones affect the walls permeability
26
describe the collecting duct
found in the medulla connects the nephron and the ureter moves out of the collecting duct by osmosis due to the concentration gradient created by active transport of minerals in the ascending loop water leaves by channel proteins adh controls water loss
27
describe movement in the loop of henle
descending limb water leaves by osmosis decreasing water potential in the tube ascending limb sodium moves out by facilitaed diffusion when the conc gradient is high and then active transport lowering water potential of the tissue surounding the tube
28
what is the hypothalamus
region of the brain which acts as a control centre of the involuntry nervous system
29
what is an osmoreceptors
cells within the hypothalmus that detects changes in blood water potential
30
what is a pituitary gland
endocrine gland situated at the base of the brain anterior (front ) and posterior ( back)
31
what is ADH
hormone produced by hypothalmus and secreted by posterior pituitary gland
32
what happens when blood water potential is too high
detected by the osmoreceptor in the hypothalmus posterior lobe of pituitary gland releases less ADH walls of collecting duct and distal convoluted tube become less permibale more urine is less concentrated water potential gradient decreases
33
what happens when blood water potential is too low
cells shrivel and this is detected by the osmoreceptors in hypothalmus posterior lobe of pituotary gland releases ADH ADH reaches collecting duct via blood making it more permiable to H2O less urine and is more concentrated
34
describe the action of ADH
binds to protiens on the surface of the cell leading to the activation of the enzyme phosphorylase casuing vesicles containing aquaporins to fuse with cell surface membrane increasing its permeability to water