Homeostasis and Bioenergetics Flashcards

(72 cards)

1
Q

what is bioenergetics

A

when cell’s chemical pathways convert foodstuffs into a biologically usable form of energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

define homeostasis

A

maintenance of a constant and normal internal environement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is considered a steady state

A
  • physiological variable is unchanging, but not necessarily normal
  • balance between demands placed on body and the body’s responses to those demeands
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are some examples of homeostasis in the body

A

body temperature regulation and arterial blood pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the intracellular control systems

A
  • protein breakdown and synthesis
  • energy production
  • maintenance of stored nutrients
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

examples of organ systems that are part of the control system within the body

A

pulmonary and circulatory systems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

define a biological control system

A

series of interconnected components that maintain a physical or chemical parameter at a near constant value

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are some components of the biological control system

A
  1. Sensor or Receptor: detects changes in variable
  2. control center: assesses input and initiates response
  3. effector: changes internal environment back to normal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

negative feedback

A

response reverses the initial disturbance in homeostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

positive feedback

A

response increases the original stimulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is “gain of a control system”

A

degree to which control system maintains homeostasis
-system with large gain is more capable of maintaining homeostasis than system with low gain (pulmonary and cardiovascular systems have LARGE gain)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does the failure of the biological control system result in

A

disease, such as type 1 diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

exercise with regards to homeostasis

A

exercise actually disrupts homeostasis by causing changes in:

  1. pH
  2. oxygen and CO2 levels
  3. temperature

control systems are capable of maintaining steady state during submaximal exercise in a cool environemtn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Adaptation
Acclimatization
Cell Signaling

A

Adaptation: change in structure or function of cell or organ system, results in improved ability to maintain homeostasis

Acclimatization: adaptation to environmental stresses

Cell Signaling: communication between cells using chemical messengers, important for maintaining homeostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what areas of the brain maintains and regulates respiration

A

pons and medulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

at what levels are you considered to be hypoglycemic

A

below 70 mg/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what what levels are you considered to be hyperglycemic

A

above 99 mg/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

list the 5 cell signaling mechanisms

A
  1. intracrine signaling: chemical messenger inside cell triggers response
  2. Juxtacrine signaling: chemical messenger passed between 2 connected cells
  3. autocrine signaling: chemical messenger acts on that same cell
  4. paracrine signaling: chemical messengers act on nearby cells
  5. endocrine signaling: chemical messengers released into blood, only affect cells with specific receptror
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what do cells create when the body is under stress such as high temp or abnormal pH

A

cells synthesize stress proteins when homeostasis is disrupted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what are the 3 forms of biologic work

A
  1. mechanical work of muscle contraction
  2. chemical work for synthesizing cellular molecules
  3. transport work that concentrates diverse substances in body fluids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

oxidation

A

a substance loses electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

reduction

A

a substance gains electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what do redox reactions power

A

the body’s energy transfer processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what is the main energy “currency”

A

ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what is a high energy phosphate compound
phosphocreatine | -releases large amounts of energy when bonds between creatine and phosphate are broken
26
how much more phosphocreatine does the body store than ATP
4-6 times as much PCr
27
what is phosphorylation
refers to the energy transfer through phosphate bonds most of the energy for ATP phosphorylation comes from oxidation of carbs, lipids, and proteins oxidative phosphorylation synthesizes ATP by transferring electrons from NADH and FADH2 to oxygen
28
what are 4 sources for ATP formation
1. glucose derived from liver glycogen 2. triglyceride and glycogen molecules stored within muscle cells 3. FFA derived from triglyceride that enter the bloodstream for delivery active muscle 4. intramuscular and liver derived carbon skeletons of amino acids
29
Characteristics of the ATP-PC system
anaerobic very rapid chemical fuel is PC very limited ATP production and muscle stores are limited used with sprinters or any short duration high power activity
30
characteristics of the lactic acid system
anaerobic rapid food fuel: glycogen limited ATP production by product is lactic acid that causes muscular fatigue used with activities of 1-2 minutes long
31
characteristics of the oxygen sytem
aerobic slow food fuel: glycogen, fats and protein unlimited ATP production, no by products used with long duration activities
32
what are the 2 stages of glucose degradation
1. anaerobic: glucose breaks down relatively rapidly to 2 molecules of pyruvate and lactic acid 2. aerobic: pyruvate degrades further to carbon dioxide and water
33
what is glycolysis
glycogen catabolism
34
glycogenolysis
glycogen to glucose
35
glucogenesis
glucose to glycgoen
36
gluconeogenesis
more ATP from non carbs
37
citric acid cycle
second stage of carb breakdown | -degrade acetyl-CoA substrate to CO2 and hydrogen atoms within the mitochondria
38
what does NAD stand for and what vitamin is it
nicotinamide adenine dinucleotide (niacin)
39
what does FAD stand for and what vitamin is it
flavin adenine dinucleotide
40
what are the proteins in the ETC
cytochromes
41
name of a plasma protein
albumin
42
what is a coupled reaction
this is a reaction that has 2 parts, one has to happen with the other, they cant just individually exist. an example would be oxidation-reduction reactions
43
what 2 molecules play an important role in the transfer of hydrogens and electrons
NAD and FAD
44
what is the oxidized form of nicotinamide adenine dinucleotide
NAD
45
what is the reduced form of nicotinamide adenine dinucleotide
NADH
46
what is the enzyme that breaks down triglycerides into fatty acids and glycerol
lipase
47
what is a type of natural steroid in the body
cholesterol
48
what amino acid can be converted to glucose in the liver
alanine
49
what enzyme catalyzes the reaction | PC+ADP-----> ATP+C
creatine kinase
50
what is the net gain of ATP from glycolysis
2
51
where does glycolysis occur
in the sarcoplasm of the muscle cell
52
what are the inputs and outputs of glycolysis
Inputs: Outputs 1. 1 glucose 2 pyruvate or 2 lactate 2. 2 ADP 2ATP 3. 2 NAD 2 NADH
53
what is LDH
LDH= lactate deydrogenase this enzyme catalyzes the reaction of pyruvic acid accepting a hydrogen atoms to form lactic acid and the reformation of NAD
54
where does aerobic production of ATP occur
in the mitochondria
55
what are the hydrogen (energy) carriers to complete the oxidation of carbohydrates, lipids, and proteins
NAD and FAD
56
term for aerobic production of ATP
oxidative phosphorylation
57
how are fatty acids oxidized into acetyl-CoA
beta oxidation
58
what enzyme is responsible for carb metabolism (breakdown from glycogen to glucose)
phosphorylase
59
name the enzyme that breaks down fat (adipose) into free fatty acids and glycerol
hormone sensitive lipase
60
what substance can be synthesized from all three energy yielding nutrients
acetyl CoA
61
what is the net ATP gained from each NADH that passes through the electron transport chain
3
62
what is the net ATP gained from each FADH that passes through the electron transport chain
2
63
what is the enzyme required to transport fat from the muscle to the cristae of the mitochondria
carnitine transferase
64
name of the plasma protein which transports free fatty acids in the blood
albumin
65
what does the acetyl portion of acetyl-CoA join with to form the citric acid
oxaloacetate
66
during lipid metabolism: | what hormones help mobilization
1. glucagon 2. growth hormone 3. testosterone 4. epinephrin
67
during lipid metabolism, where are the uptake receptors
on the sarcolemma
68
what plays a role as an energy substrate during endurance activities and heavy training
protein
69
define deamination
nitrogen is removed from the amino acid molecule
70
define transamination
when an amino acid is passed to another compound
71
what are the remaining carbon skeletons do once proteins have been deaminated and transaminated
they enter metabolic pathways to produce ATP
72
what does protein catabolism facilitate
water loss