homeostasis and response - HOMEOSTASIS Flashcards

thermoregulation, body temperature, losing/gaining heat, sugar regulation, blood glucose + controlling it, diabetes, osmoregulation/ADH, kidney transplants, hormones/puberty in females (48 cards)

1
Q

TR
core body temperature

A

vital organs deep in the body like liver, kidneys, heart are maintained at 37 degrees C
(70% of your energy is used to keep this up)

skin temperature at body extremities (toes, fingers) are usually lower than core body temp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

TR
more or less tired on a cold day?

A

on a cold day, you’d be focusing your energy on generating more heat so you’d be more tired and hungry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

TR
how can heat be gained

A
  • movement and exercise
  • shivering
  • vasoconstriction (turning blue)
  • wearing extra clothes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

TR
how can heat be lost

A
  • sweating
  • vasodilation (turning red)
  • removing extra clothing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

TR
how is temperature controlled (receptors, hypothalamus)

A

body temp is monitored and controlled by temperature receptors in the skin & brain
–> they detect changes in the temperature of blood flowing through those areas

the thermoregulatory centre is in the brain
if body temp deviates from 37 degrees C:

the hypothalamus & skin receptors send out electrical signals
these trigger actions or behaviour that increase or decrease heat loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

TR
why do we shiver/get goosebumps

A

when core body temperature drops, muscles begin to twitch (rapidly contract and relax) –> shivering
shivering generates heat which raises body temperature

goosebumps involuntarily appear when someone becomes cold
they are caused by tiny muscles at the base of body hairs pulling the hairs erect
the upright hairs trap an insulating layer of air which helps reduce heat loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

TR
vasoconstriction/warming up
why do people go pale when cold?

A

when core body temperature falls, blood vessels in the skin get narrower - vasoconstriction
–> this reduces the volume of blood flowing near the skin surface so blood runs deeper and reduces the amount of heat loss from the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

TR
vasodilation/cooling down
why do people turn red when hot?

A

when core body temperature rises, blood vessels in the skin get wider - vasodilation
–> this allows a larger volume of blood to flow near the surface of the skin, transferring heat to the environment and cooling the body down

additional cooling occurs with production of sweat from sweat glands –> as sweat evaporates, it transfers heat away from the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

TR
negative feedback control of body temperature

A

BODY TEMP FALLS

skin sensory nerve endings stimulated
hypothalamus detects change in blood temperature

impulse sent to muscles and skin

shivering (muscle contraction, increased metabolism and relaxation) and vasoconstriction begin

BODY TEMP RISES

skin sensory nerve ending stimulated
hypothalamus detects change in blood temperature

impulse sent to muscles and skin

sweating (losing water through pores in skin to cool by evaporation) and vasodilation begin

BODY TEMP FALLS…..

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

homeostasis meaning

A

the process of keeping things the same
a series of automatic control systems ensures that the body maintains a constant temperature and steady levels of water, ions, and blood sugar.

homeostasis allows the body’s cells to work at their optimum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

glucose

A

a type of sugar used by the body to provide energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

glycogen

A

a storage substance made of glucose stored in the liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

insulin

A

a hormone (chemical messenger) that tells your body to change glucose –> glycogen
made in the pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

glucagon

A

a hormone that tells your liver to change glycogen BACK –> glucose
made in the pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what affects blood glucose

A
  • eating - rise
  • vigorous exercise - fall
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

dangers of high/low blood glucose

A

excess glucose - makes blood plasma and tissue fluid around cells TOO CONCENTRATED
–> this can severely damage cells e.g. causing crenation (collapsing) in red blood cells

low blood sugar can make cells swell up and burst - lysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

negative feedback controlling blood glucose levels

A

BLOOD GLUCOSE LEVELS RISE

Pancreas realises that glucose levels are too high

Pancreas releases insulin (chemical messenger) towards Liver through the bloodstream

Liver receives the message so decreases levels of glucose in blood by taking glucose molecules from the bloodstream and sticking it together* to create glycogen
Liver stores it

*takes a soluble molecule that affects osmosis - sticks it together - creates an insoluble molecule that doesn’t affect osmosis

BLOOD GLUCOSE LEVELS FALL

Pancreas realises that the glucose levels are now too low

Pancreas releases glucagon (chemical messenger) through the bloodstream to Liver

Liver receives the message so takes the stored glycogen and splits it up into glucose again and releases it into the bloodstream to increase the blood glucose levels

BLOOD GLUCOSE LEVELS RISE…

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

type 1 diabetes
- symptoms and treatment

A

pancreas unable to produce insulin

symptoms:
- frequent urination
- thirst
- fatigue
- confusion
- collapse

treatment
- control
- frequent blood sugar testing
- high sugar –> inject insulin
- stem cell transplant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

type 2 diabetes
- treatment

A

liver/muscles no longer recognise insulin produced by pancreas

treatment:
- older people - treated with tablets
- metformin persuades liver/muscles to recognise insulin
- regular exercise + healthy diet
- lifestyle change

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

where do you gain and lose water

A

gain
- respiration in cells (350cm^3)
- drinks (1450cm^3)
- food (800cm^3)

loss
- faeces (100cm^3)
- exhaled air (400cm^3)
- sweat (600cm^3)
- urine (1500cm^3)

21
Q

what is the job of the kidney

A

to balance the amount of water it takes in with the amount it gets rid of

22
Q

what happens when you don’t drink enough water

A

in hot weather
- lose water as sweat to keep you cool
- kidney produces small amounts of concentrated urine using less water in the body
- you become thirsty to increase water consumption
- water levels then increase due to ADH and thirst

23
Q

what happens when you drink too much water

A
  • too much water in the body
  • use the toilet a lot
  • kidney produces a large volume of dilute urine
  • water levels decrease due to lots of urine and ADH
24
Q

what does the hormone ADH do

A

it controls the amount of water in your urine and is made by the pituitary gland in the brain when you need to keep water in your body

25
when you are dehydrated how much ADH is released
more ADH is released and concentrated urine is produced
26
when you are overhydrated how much ADH is released
less ADH is released and dilute urine is produced
27
what are the 3 kidney stages (no explanation)
filtration selective reabsorption urine formation
28
what is filtration in the kidneys (1)
the RENAL ARTERY branches and ends with lots of capillaries called the GLOMERULUS (inside the nephron). as blood passes through each glomerulus, it is filtered. due to HIGH PRESSURES, SMALL MOLECULES are filtered out of the glomerulus and blood and passed into the nephron
29
what is selective reabsorption in the kidneys (2)
the kidneys SELECTIVELY REABSORBS molecules, only those which the body needs, back into the blood stream from the nephron. this happens by active transport (energy from respiration is needed for reabsorption)
30
what is urine formation in the kidneys (3)
the molecules which are NOT selectively reabsorbed (urea, excess water, ions) form your urine
31
normal blood water levels increase... what happens next
blood water levels increase - receptors detect and pituitary gland releases less ADH - kidney reabsorbs less water. urine is more dilute - blood water levels reduce. decreased ADH secretion stops
32
normal blood water levels decrease... what happens next
blood water levels decrease - receptors detect and pituitary gland releases more ADH - kidney reabsorbs more water. urine is less dilute and more concentrated - blood water levels increase. increased ADH secretion stops
33
where is a replacement kidney usually attached
it is usually placed in the groin and attached to the blood vessels and the bladder - the ureter carries urine from the new kidney to bladder
34
what has to be special about the donor kidney and why
the kidney has to be very similar to to the patient's tissue type because rejection is a major problem with transplantation. the recipients immune system could recognise it as nonself and try to destroy it.
35
how do you choose a patient for a kidney transplant
your tissue type is determined the antigens on the surface of every cell the antigens on every kidney donor are analysed and matched with a similar recipient
36
how do you reduce infection risk during kidney transplantation
immunosuppressant to prevent rejection however is weakens your immune system
37
advantages/disadvantages of dialysis and transplantation
dialysis DISADVANATAGE - each session takes 6 - 10 hours and 3 times a week - patients have to strictly restrict diet and fluids transplant ADVANTAGE - majority of UK supports organ donation - person can survive well with 1 kidney DISADVANTAGE - shortage of donors - kidney must be transplanted within 12 hours - rejection possibility - have to: imitate recipient's bone marrow do drug treatment keep in sterile conditions to minimise rejection risk
38
when does puberty happen in males and females
testes make testosterone and this stimulates produce of sperm in boys ovaries make oestrogen and start to release eggs in girls
39
what changes happens to males and females during puberty
males broader shoulders hair on face/legs/genitals enlarged genitalia voice deepens skin changes girls breasts develop hips widen hair skin changes
40
what are the 2 main things hormones do
stimulate egg release inhibit egg release
41
4 stages of menstruation
1 - lining of uterus breaks down and bleeding begins 2 - stretches from day 4 to 14, when lining is repaired 3 - on day 14, the egg is released from the ovary 4 - the maintenance stage where the uterus is maintained in case the egg is fertilised
42
what are the 4 sets of hormones
follicle stimulating hormone (FSH) oestrogen luteinizing hormone (LH) progesterone
43
what is the hormone - follicle stimulating hormone (FSH) responsible for
- it is made by the pituitary - stimulates the development of an ovum - stimulates ovaries to produce oestrogen
44
what is the hormone - oestrogen responsible for
- thickens the lining of the uterus - inhibits production of FSH - stimulates pituitary to produce LH
45
what is the hormone - luteinizing hormone (LH) responsible for
- produced by pituitary - stimulates the release of an egg
46
what is the hormone - progesterone responsible for
- carries on maintaining the endometrial lining of the uterus for a potential pregnancy - stops a new follicle developing
47
negative feedback loop of the puberty hormones
FSH made by pituitary --> eggs GROW inside follicle --> oestrogen made by ovary stimulates the pituitary to make LH --> oestrogen stops making FSH and the cycle restarts OR!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! --> lining of uterus thickens LH made by pituitary --> progesterone made by ovary - if pregnant, progesterone and oestrogen continue to be produces - if not pregnant, progesterone production stops and menstruation occurs cycle starts again
48