Hormone-Related Conditions

Question 1

What is Hirsutism?

Answer 1

Male-pattern hair growth in women

Question 2

What are common causes of Hirsutism?

Answer 2

Medications
Emotional distress/depression
PCOS
Cushing syndrome
Congenital adrenal hyperplasia
Androgen use
androgen-secreting tumor
carcinoma

Question 3

What medications are commonly associated with Hirsutism?

Answer 3

Minoxidil
Valproic Acid
Phenytoin

Question 4

What are symptoms of Virilization?

Answer 4

Clitoromegaly
Deeping of the voice
Irregular menstrual periods
acne
increased muscle mass

Question 5

What testing should be done when patients present with irregular periods and signs of virilization?

Answer 5

Prolactin
DHEA
Testosterone
FSH/LH
17-Hydroxyprogesterone

Question 6

How do you manage Hirsutism?

Answer 6

OCP, antiandrogens, metformin in PCOS

Question 7

What is the #1 cause of Oligomenorrhea in the United States?

Answer 7

PCOS

Question 8

What are the criteria used to diagnose PCOS?

Answer 8

Clinical hirsutism and/or high testosterone/DHEA
Irregular Menstruation
10 Cysts on pelvis US with enlarged ovary >10cm

Needs 2 of the 3 criteria

Question 9

How is PCOS treated?

Answer 9

Metformin

BP, lipid, glucose management

OCP with progesterone: regulate menstruation

Spironolactone (last-line)