hormones and diseases of the digestive system Flashcards

(50 cards)

1
Q

the major gastro hormones

A
  1. gastrin,
  2. enterogastrone,
  3. secretin,
  4. cholecystokinin pancreozymins,
  5. duocrinin
  6. enterocrinin
  7. vasoactive intestinal peptide
  8. somatostatin
  9. pancreatic polypeptide
  10. villikinin
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2
Q

gastrin

A

from stomach
target stomach
release of gastric juices

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3
Q

enterogastrone

A

gastric inhibitory
from duodenum
target stomach
slows gastric contraction and inhibits its secretions

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4
Q

secretin

A

the first hormone discovered
from duodenum
target pancreas liver and stomach
release bicarbonates in pancreatic juice, release bile and suppress gastric juice

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5
Q

cholecystokinin pancreozymins(CCK-PZ)

A

from small intestine
target gall bladder and pancreas
contracts the gall bladder to release bile
signals the pancreas to release pancreatic juices

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6
Q

duocrinin

A

from duodenum
target duodenum
signals Brunner’s glands to secrete mucus

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7
Q

enterocrinin

A

from small intestine
target small intestine
signals crypts of lieberkuhn to secrete intestinal juices

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8
Q

vasoactive intestinal peptide

A

from small intestine
target small intestine and stomach
dilates peripheral blood vessels of the gut
inhibits gastic acid secretion

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9
Q

somatostatin(part 1)

A

from delta cells of islets of Langerhans
target to pancreas and GI tracts
inhibits the secretion of glucagon by alpha cells and insulin by beta cells
inhibits absorption of nutrients from GI tract

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10
Q

villikinin

A

from small intestine
target small intestine
accelerates movements of villi

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11
Q

somatostatin(part 2)

A

from argentaffin cells of gastric and intestinal glands
target GI tract
suppresses the release of hormones from the GI tract

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12
Q

pancreatic polypeptide(PP)

A

from pancreatic polypeptide cells
to pancreas
inhibits the release of pancreatic juice from the pancreas

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13
Q

the chief source of energy/metabolic fuels in humans

A

carbohydrates, proteins and fats

they are oxidised and transformed to ATP,the chemical energy drives the cells

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14
Q

whats gross calorific value

A

amount of heat produced on combustion of 1 g of food

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15
Q

the calorific value of carbohydrates, proteins, fats

A
  1. 1kcal/g
  2. 65kcal/g
  3. 45kcal/g
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16
Q

physiological value of food

A

4kcal/g for proteins and carbohydrates and 9kcal for fats

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17
Q

PEM

A
protein energy malnutrition
deficiency of vitamin,iron and iodine,energy,protein
young children(0-6 years) require more protein than adults
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18
Q

two types of PEM

A

kwashiorkor and marasmus

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19
Q

kwashiorkor

A
protein deficiency
1-5 years age
wasted muscle
thin limbs 
regarding growth
water retention in legs
reddish hair,diarrhoea and pot belly
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20
Q

marasmus

A
protein and calorie deficiency
infants below the age of 1
impaired growth and replacement of tissue proteins
thin limbs
prominent limbs
dry thin wrinkled skin
diarrhoea
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21
Q

vitamin A(retinol)

A

carrot,tomato,papaya,mango,milk,eggs,cod liver oil
vision,growth and diff of epithelial tissue
deficiency:night blindness ,xerophthalmia,abnormal epithelial cell growth
first fat soluble vitamin discovered

22
Q

vitamin D(calciferol)

A

cod liver oil,skin(in the presence of sunlight)
absorption of ca ions from the GI tract and calcium deposition in bones
deficiency: rickets in children and osteomalacia in adults
behaves more like a hormone rather than cofactor of an enzyme

23
Q

vitamin E (tocopherol)

A

wheat germ, green leafy veggies, fats of vegetable origin
good antioxidant, necessary for the proper functioning of the reproductive organs and muscles, maintaining the structure of RBC
deficiency: reproductive failure

24
Q

vitamin K derivatives

A

k1(phylloquinone)
k2 (menaquinone)
k3 (menadione)-synthetic

25
vitamin k
leafy vegetables, wheat germ, bacteria of large intestine helps in blood clotting deficiency: excessive bleeding interesting fact: meliotus indica (fodder and green manure ) contains a green substance called dicumarol that prevents the action of vit k
26
fat soluble vitamins
a,k,d,e
27
water soluble vitamins
b,c
28
vitamin B1 (thiamine)
whole grain,wheat germ,legumes,nuts,fish essential for growth and repair of tissues deficiency:beri-beri in alcoholics it causes the disease Wernicke's syndrome and korsakoffs's syndrome , as alcohol interferes with B1 metabolism in liver
29
vitamin B2(riboflavin)
aka yellow enzyme milk cheese meat eggs legumes wheat germ mushrooms green leafy veg helps RBC production and acts as FAD(in ETC and TCA cycle) and as FMN( in ETC) deficiency:cheliosis
30
vitamin B3(niacin)
whole grain nuts,legumes,fish,meat poultry,liver ,yeast nad and nadp in TCA cycle deficiency: pellagra
31
vitamin B5(pantothenic acid)
yeast, milk, egg yolk, wheat germ, meat, honey, groundnut, tomatoes for healthy skin and hair, it forms coenzyme A in the TCA cycle deficiency: dermatitis, loss of hair, greying of hair
32
vitamin B6(pyridoxine)
whole grain ,cerelas,peanuts,banana,soybean,meat.vegetables protein metabolism deficieny: retarded growth,anaemia,dermatitis,nausea
33
biotin(vitamin B7)
egg yolk,milk,nuts,honey,liver,meat,fish carbs and fat protein metabolism deficiency:poor growth,loss of muscular control,weight loss, loss of appetite,hair fall the white of the egg contains avidin protein which degrades this vitamin
34
vitamin B9 (folic acid)
green leafy vegetables essential for the formation of RBC,increase appetite deficiency: megaloblastic anaemia
35
vitamin B12(cyanocobalamin)
spirulina,liver,meat,eggs.fish.milk rbc production,DNA synthesis, proper functioning of the neurological system deficiency: pernicious anaemia
36
vitamin B17(laetrile)
wheat grass juice | anticancer property
37
vitamin C(ascorbic acid)
citrus,amla,chillies,guava,tomato essential for the formation of RBC,production of antibodies,bones,teeth,gums and acts as an antioxidant deficiency:scurvy alcoholics are low in vitamin C
38
jaundice
yellowing of skin,eyes liver damage extra bilirubin in blood
39
vomiting
antiperistalsis of stomach contents,reflex action induced by the medulla
40
diarrhoea
frequency of bowel movements and liquidity of faecal matter | reduced absorption of food
41
constipation
poop retained in the rectum
42
indigestion
anxiety, food poisoning, deficiency of enzymes, overeating, spicy food cause the food not be broken down fully
43
heartburn
acid reflux in the oesophagus that feels like the heart burning
44
appendicitis
inflammation of the appendix that it might burst and release bacteria and can cause death
45
hernia
protrusion of the intestine in the inguinal canal
46
nausea
discomfort while vomiting due to distension of the stomach
47
Basal metabolic rate
the minimum energy required for maintaining body during rest or sleep 1600 kcal/day
48
routine metabolic rate
the energy requirement of a moderately active person | 2200 -2800 kcal/day
49
choleretic
increased bile secretion from the liver
50
achalasia cardia
failure of the cardiac sphincter and therefore the accumulation of food in the proximal part of the oesophagus distends the oesophagus