human disease Flashcards
(17 cards)
inhale/ingest viral particles
adhere to host respiratory epithelium
subject to mutation and assortment
antigenic-drift/shift
influenza
varicella-zoster virus
has the ability to go into latency
chickenpox
herpes zoster
reactivated form of chicken pox
shingles
rubeola
koplik’s spots: red lesions with bluish-white speck in the center
measles
orthopoxvirus
transmitted by direct and fairly prolonged face-to-face contact
small, red spots that get larger and filled with thick opaque fluid
smallpox
key proteins: spike, nucleocapsid, and proteases
host responds to virus and then responds to own inflammatory response, increase in pro-inflammatory cytokines
COVID-19
transmitted through bodily fluids
Kaposi’s sarcoma: bulgy red dots on the skin
no cure but drugs can suppress replication cycle points
HIV/AIDS
blisters around lips
go through active infection w/ multiplication OR latent to tri-geminal ganglion
cold sores (HSV-1)
very common sexually transmitted disease
genital herpes (HSV-2)
very common sexually transmitted HPV
high-risk strains can cause cancer and warts
genital warts
caused by Epstein-Barr virus
spread by mouth-to-mouth contact
infects B cells
mononucleosis
inflammation of stomach/intestines
transmitted fecal-orally
leading cause of childhood death in developing countries
ex. norovirus
viral gastroenteritis
poliovirus
multiplies in throat/small intestine
very stable and can remain infectious in food/water
poliomyelitis
cause viral hemorrhagic fever
spread via contact w/ bodily fluids
bats = natural reservoirs
ebola
african bat = reservoir host
affects humans and primates
marburg disease
neurotropic virus
primary transmitted by bites of infected animals
pain to encephalitis (CNS)
PNS + salivary glands (shedding)
neurological symptoms
paralysis and death
rabies
plasmodium falciparum
transmitted by bite of an infected female mosquito
have one allele of sickle cell disease = more resistant
malaria
