Human Echoviruses Flashcards

1
Q

Classification

A

Family: Picornaviridae

Genus: Enterovirus

Species: echo virus

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2
Q

Characteristics

A
Naked
\+ssRNA
No virion polymerase
Cytoplasmic replication 
Many serotypes
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3
Q

Transmission

A

Faecal oral route

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4
Q

Pathogenesis

A

Replication:
Oropharynx
Payer’s patches (GIT)

Primary viremia:
Bloodstream

Secondary viremia:
Meninges
Skin
Muscles

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5
Q

diseases

A

Rashes (young children)
Respiratory diseases
Aseptic meningitis (young children)
Pericarditis

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6
Q

Microscopical diagnosis

A

Cell cultures in monkey kidney tissue —> CPE

Identification —> neutralisation tests

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7
Q

Treatment and prevention

A

No antiviral therapy available

No vaccine available

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