Humoral/cellular Immune Responses

Question 0

Opsonized by IgM, G with complement

–> PMN and macrophages kill

Answer 0

-itis

EC bacteria:

• staph
• strep
• neisseria
• haemophilus
• bordatella
• e.coli

Question 1

Neutralized by IgM, G, A –> clearance

Answer 1

• Exotoxins
• Some viruses (polio)
• Some obligate IC bacteria (rickettsia)

Question 2

Killed by macrophages through IFN-γ

CD4 Th1 activating macrophages

Answer 2

-osis

Most facultative IC bacteria:

• mycobacterium (tb)
• salmonella (typhoid fever)
• brucella

Most fungi
Most parasites (Protozoa, encysted tissue worms)
Some viruses

Question 3

Killed by CD8 cytotoxic response

Answer 3

• Virus infected cells that show foreign viral Ags
• Listeria (IC bacteria)
• Foreign transplants