HY Tumors Flashcards
(14 cards)
squamous cell carcinoma
smoking? location? pathology? paraneoplastic? Tx?
Smoking. Central. CAVITATING. Keratin pearls, intercellular bridges. TTF -, Calrentin - Paraneoplastic: hypercalcemia Tx: surgery
adenocarcinoma
smoking? location? pathology? paraneoplastic? Tx?
No smoking association. Peripheral. Glandular, TTF+, calrentin - Not paraneoplastic. Tx: surgery
adenocarcinoma in situ
smoking? location? pathology? paraneoplastic? Tx?
No smoking association. Slow growing. Ground glass. Not paraneoplastic. Tx: surgery
large cell carcinoma
No association w smoking.
Peripheral.
Undifferentiated
small cell carcinoma
smoking? location? pathology? paraneoplastic? Tx?
Strong association with smoking.
Central.
TTF+, “grinding” cells, little cytoplasm.
Neuroendocrine.
Paraneoplastic: SiADH, ACTH (Kushing, hyperglycemia), Abs (Lambert-Eaton, myasthenia-like)
Tx: chemo + radiation
carcinoid
smoking? location? pathology? paraneoplastic? Tx?
No smoking association.
Central or peripheral.
TTF+, neuroendocrine cells.
pulmonary hamartoma
Peripheral.
CARTILAGE (endobronchial mass), well circumscribed.
pleural tumors
pleural plaques –> no nuclear detail
dense collagen bands
malignant mesothelioma
Peripheral.
White, rind-like.
Plump epitheliod cell.
TTF -, calrentin +
oral cavity, oropharynx
SCC
upper cervical lymphadenopathy
alcohol, tobacco, HPV, sun lip exposure
nasopharyngeal
Non keratinizing squamous, undifferentiaed.
SCC, keratinized
Basaloid squamous cell carcinoma,
EBV
laryngeal
SCC
HPV, alcohol, tobacco
nasal polyps
benign neoplasm
cavitating
squamous cell
