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module 2a > hyperlipidemia lab > Flashcards

hyperlipidemia lab Flashcards

(54 cards)

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1
Q

vytorin

A

simvastatin with ezetimibe

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2
Q

juvisync

A

simvastatin with sitagliptin

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3
Q

fluvastatin brand

A

lescol

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4
Q

fluvastatin dosing

A

low: 20-40 mg/day
moderate: 80 mg/day

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5
Q

pitavastatin brand

A

livalo

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6
Q

pitavastatin dosing

A

low: 1 mg/day
moderate: 2-4 mg/day

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7
Q

lovastatin brand

A

mevacor

altoprev

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8
Q

lovastatin dosing

A

low: 20 mg/day
moderate: 40 mg/day

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9
Q

pravastatin brand

A

pravachol

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10
Q

pravastatin dosing

A

low: 10-20 mg/day
moderate: 40-80 mg/day

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11
Q

simvastatin brand

A

zocor

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12
Q

simvastatin dosing

A

low: 10 mg/day
moderate: 20-40 mg/day

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13
Q

atorvastatin brand

A

lipitor

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14
Q

atorvastatin dosing

A

moderate: 10-20 mg/day
high: 40-80 mg/day

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15
Q

rosuvastatin brand

A

crestor

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16
Q

rosuvastatin dosing

A

moderate: 5-10 mg/day
high: 20-40 mg/day

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17
Q

statin SE

A
  • Myopathy
  • Rhabdomyolysis
  • Myositis
  • Muscle pain
  • Liver enzyme abnormalities
  • HA
  • Dyspepsia
  • Abdominal pain
  • Nausea
  • Upper respiratory infection
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18
Q

statin monitoring

A
  • FLP: Baseline, 4-12 weeks after starting, Every 3-12 months
  • CK: Baseline, If muscle symptoms
  • LFTs: Baseline, Repeat if indicated
  • Skeletal Muscle SEs
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19
Q

ezetimibe brand

A

zetia

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20
Q

ezetimibe dosing

A

10 mg/day

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21
Q

ezetimibe SE

A
  • Arthralgia
  • Upper respiratory tract infection
  • Diarrhea
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22
Q

ezetimibe monitoring

Study These Flashcards
A
  • FLP baseline

- LFTs

23
Q

alirocumab brand

24
Q

alirocumab dosing

Study These Flashcards
A
  • 75 mcg SQ q2weeks

- 150 mcg SQ q2weeks post 4-8 weeks

25
evolocumab brand
repatha
26
evolocumab dosing
120 mcg SQ q2 weeks | 420 mcg SQ monthly
27
PCKS9 inhibitor SE
- GI side effects - ↑ LFT - Injection site reaction - Myalgia - Influenza
28
PCKS9 inhibtor monitoring
- LDL-C within 4-8 weeks of starting or changing dose | - Hypersensitivity
29
omega-30acid ethyl esters brand
lovaza
30
omega-30acid ethyl esters brand dosing
- 4 g/day | - 2 g BID
31
omega-30acid ethyl esters brand SE
- GI – diarrhea - Dysgeusia - Dyspepsia - Eructation - Nausea
32
omega-30acid ethyl esters brand monitoring
- TG and LDL at baseline and periodically - ALT periodically - GI disturbances, skin changes, bleeding
33
cholestyramine brand
Questran | Prevalite
34
cholestyramine dosing
4g (1 packet or scoop) once or BID | -MAX: 24 g/day
35
colesevelam brand
welchol
36
colesevelam dosing
3. 75 g QD | 1. 875 g BID
37
colestipol brand
colestid
38
colestipol dosing
- start: 5g once or BID - increase by 5g at 1-2 month intervals - go up to 30g/day in divided doses
39
colsevelam, cholestyramine and colestipol SE
- increased TG - Constipation - Bloating - Nausea - Flatulence - deceased absorption of fat-soluble vitamins - Hypernatremia - Hyperchloremia - GI Obstruction
40
colsevelam, cholestyramine and colestipol monitoring
- FLP: Baseline, 3 months after, q6—12 months after | - Should not use if TG >300 mg/dL
41
niacin brand
niacor niaspan slo-niacin
42
niacin dosing
- start: 500 mg QHS x4 weeks - go to 1g QHS x4 weeks - MAX: 2g/day - usual: 1-2 g/day QHS
43
niacin SE
- Prostaglandin mediated flushing and itching - Skin rash - Upset stomach - Low blood pressure when standing
44
niacin monitoring
- LFT baseline - FBH or A1C - Uric acid - Monitor during titration and every 6 months after
45
gemfibrozil brand
lopid
46
gemfibrozil dosing
600 mg BID 30 min AC
47
fenofibrate brand
tricor
48
fenofibric acid brand
trilipix | fibricor
49
tricor dosing
48-145 mg/day | MAX: 145 mg/day
50
trilipix dosing
45-135 mg/day | MAX: 135 mg/day
51
fibricor dosing
35-105 mg/day | MAX: 105 mg/day
52
fibrate SE
- GI disturbances - Rash - Myalgia - Dizziness - Anemia, leukopenia, thrombocytopenia - Renal insufficiency
53
gemfibrozil monitoring
- Serum cholesterol - LFTs - CBC – first year
54
fenofibrate and fenofibric acid monitoring
- Periodic blood cell count – first year - FLP every 6-8 weeks until goal then every 4-6 months - LFTs - Renal function: Baseline, 3 months after, Every 6 months - Adjust following lipid determinations at 4-8 week intervals - Consider reducing if lipids significantly lower than target

module 2a (13 decks)

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