Hypersensitivity Reactions Flashcards
(9 cards)
Which cells are involved in a type 1 hypersensitivity reaction?
Mast cells (degranulation due to IgE)
Give one example of a type 1 hypersensitivity reaction
Allergy
Anaphylaxis
Hayfever
Which cells are involved in a type 2 hypersensitivity reaction?
IgG and IgM (antibodies) activate the complement system
Give one example of a type 2 hypersensitivity reaction
Haemolytic disease of the newborn
Autoimmune disease such as Grave’s disease, pernicious anaemia, myasthenia gravis
Goodpastures
Which cells are involved in a type 3 hypersensitivity reaction?
Immune complexes (antibody-antigen complexes)
Give one example of a type 3 hypersensitivity reaction
Rheumatoid arthritis
SLE
Post-streptococcal GN
Serum sickness
Which cells are involved in a type 4 hypersensitivity reaction?
T-cells
Give one example of a type 4 hypersensitivity reaction
Graft reaction
Mantoux/TB
Scabies
Contact dermatitis
Which type of hypersensitivity reaction occurs in haemolytic disease of the newborn?
Type 2
