Hypertension

Question 1

Enalapril

Answer 1

ACE inhibitor

Question 2

ACE inhibitors indications

Answer 2

Congestive heart failure, arterial hypertension, myocardial infarction, chronic kidney failure

Question 3

Candesartan

Answer 3

Angiotensin 2 receptor blocker (ARB)

Question 4

Ibesartan

Answer 4

Angiotensin 2 receptor blocker (ARB)

Question 5

Valsartan

Answer 5

Angiotensin 2 receptor blocker (ARB)

Question 6

Olmesartan

Answer 6

Angiotensin 2 receptor blocker (ARB)

Question 7

Nifedipine

Answer 7

Inhibit the vascular L-type calcium channels by binding to the alpha1 subunit.

Question 8

ARBs indication

Answer 8

Congestive heart failure, arterial hypertension, myocardial infarction, chronic kidney failure

Question 9

Amlodipine

Answer 9

Inhibit the vascular L-type calcium channels by binding to the alpha1 subunit.

Question 10

Dihydropyridines indications

Answer 10

Arterial hypertension, prinzmetal’s vasospastic angina, Raynaud’s syndrome, chronic stable angina (amlodipine), hypertensive emergency (nifedipine)

Question 11

Verapamil

Answer 11

A phenylalkylamine. Inhibition of the cardiac L type calcium channels by binding to the alpha1-subunit.

Question 12

Gallopamil

Answer 12

A phenylalkylamine. Inhibition of the cardiac L type calcium channels by binding to the alpha1-subunit.

Question 13

Diltiazem

Answer 13

Inhibit both the vascular and cardiac L-type calcium channels.

Question 14

Phenylalkylamine indications

Answer 14

arterial hypertension, coronary sclerosis dependent angina, supraventricular tachyarrhythmia

Question 15

Diltiazem indications

Answer 15

Arterial hypertonicity, coronary sclerosis-dependent angina, vasospastic angina, supraventricular tachyarrhythmia

Question 16

Atenolol

Answer 16

Selective beta1-receptor blocker

Question 17

Metoprolol

Answer 17

Selective beta1 receptor blocker

Question 18

Propanolol

Answer 18

Beta receptor blocker

Question 19

Beta blockers indication

Answer 19

Arterial hypertonicity
Sinus tachycardia
Atrial fibrillation
Supraventricular tachycardia
Following a myocardial infarction
Angina pectoris

Question 20

Bosartan

Answer 20

Endothelin receptor antagonist. Prevents the interaction of endothelin and its receptor, preventing the calcium release into the SMC.

Question 21

Ambrisentan

Answer 21

Endothelin receptor antagonist.

Question 22

Macitentan

Answer 22

Endothelin receptor antagonist.

Question 23

Endothelin receptor antagonist indication

Answer 23

Pulmonary hypertension

Question 24

Riociguat

Answer 24

Guanylate stimulator. Increases the cGMP and thereby reduces the calcium levels (induces relaxation)

Question 25

Sildenafil

Answer 25

Phosphodiesterase 5 inhibitor. cAMP can no longer be broken down

Question 26

Tadalafil

Answer 26

Phosphodiesterase 5 inhibitor. cAMP can no longer be broken down

Question 27

PDE5 inhibitors indication

Answer 27

Pulmonary hypertension

Question 28

Iloprost

Answer 28

Prostaglandin 1 analogue. Directly activate prostaglandin receptor and thereby enhances the cAMP signaling, reduces calcium and causes relaxation of the SMC.

Question 29

Alpostadil

Answer 29

PGE1 analogue. Directly activate prostaglandin receptor and thereby enhances the cAMP signaling, reduces calcium and causes relaxation of the SMC.

Question 30

Prostaglandin analogues indications

Answer 30

Pulmonary hypertension Arterial obstruction

Question 31

Selexipag

Answer 31

Prostacyclin IP receptor (PGI2) agonist. Causes the upregulation of cAMP and thereby reducing the calcium levels. Relaxation is induced.