Hypertension introduction

Question 1

Pts at high risk of PET

75 mg aspirin

Answer 1

• Hypertensive disease during a previous pregnancy
• Chronic kidney disease
• Autoimmune disease such as systemic lupus erythematosis or antiphospholipid syndrome
• Type 1 or type 2 diabetes
• Chronic hypertension

Question 2

Women with PET and recurrence risk

Answer 2

• Gestational hypertension in a future pregnancy ranges from about 1 in 8 (13%) to about 1 in 2 (53%) pregnancies
• Pre-eclampsia in a future pregnancy is up to about 1 in 6 (16%) pregnancies
• Pre-eclampsia in a future pregnancy is about 1 in 4 (25%) pregnancies if their pre-eclampsia was complicated by severe pre-eclampsia, HELLP syndrome or eclampsia and led to birth before 34 weeks, and about 1 in 2 (55%) pregnancies if it led to birth before 28 weeks.

Question 3

Hypertension in pregnancy

Answer 3

• 1 in 20 (5%) of PET pts are admitted to ITU
• 1 in 20 stillbirths are to pts with PET
• 1 in 250 (0.4%) in their first pregnancy will give birth before 34 weeks as a consequence of pre-eclampsia - 8 –10% of all preterm births result from hypertensive disorders
• Half of women with severe pre-eclampsia give birth preterm
• 20–25% of preterm births and 14–19% of term births in women with pre-eclampsia are less than the tenth centile of birth weight for gestation

Question 4

Pts at moderate risk of PET

75 mg aspirin

Answer 4

• First pregnancy
• Age 40 years or older
• Pregnancy interval of more than 10 years
• Body mass index (BMI) of 35 kg/m2 or more at first visit
• Family history of pre-eclampsia
• Multiple pregnancy.