Hypertensive Emergency

Question 1

Which 2 drugs are used for Hypertensive Emergency?

Answer 1

Nitroprusside and Fenoldapam

Question 2

What molecule involved in aerobic respiration can be blocked in Cyanide Toxicity?

Answer 2

Cytochrome C Oxidase aka Complex IV.

Question 3

Which two toxicities block Cytochrome Oxidase C?

Answer 3

Cyanide and Carbon Monoxide

Question 4

What are Sxs of Cyanide Toxicity?

Answer 4

Altered mental state, HA, N/V, Coma/Seizures

Question 5

What is the treatment for Cyanide toxicity?

Answer 5

Sodium thiosulfate.

Question 6

Which receptor does Fenoldapam act on and where?

Answer 6

D1 receptor in coronaries, peripheral, renal, splanchnic beds. Causes massive immediate decrease in blood pressure.

Question 7

When is Fenoldapam indicated?

Answer 7

Hypertensive crisis or post-op HTN.

Question 8

When is Fenoldapam contraindicated?

Answer 8

Hypotension, Natriuresis. Can also cause reflex tachycardia.

Question 9

Which drugs are preferred in HTN emergency if pt has acute renal failure?

Answer 9

hypertensive emergency and acute renal failure are clevidipine, fenoldopam, and nicardipine.