Hypothyroidism

Question 1

Ferrous sulphate / calcium carbonate tablets must be taken how many hours apart from levothyroxine?

Answer 1

4

Question 2

3 hallmark signs of Hashimoto’s?

Answer 2

hypothyroidism
goitre
anti-TPO

Question 3

two autoantibodies found in Hashimoto’s

Answer 3

anti-TPO
anti-thyroglobulin

Question 4

management of hypothyroidism and dose

Answer 4

levothyroxine 50-100

Question 5

dose of levothyroxine in over 50, cardiac disease or severe case

Answer 5

25

Question 6

how much is dose increase by during pregnancy

Answer 6

25-30

Question 7

what is subclinical hypothyroidism?

Answer 7

raised TSH, normal T4

Question 8

management of subclinical hypo

Answer 8

offer 6 months of levothyroxine IF

-TSH 5.5-10
-<65 years old
-2 readings 3 months apart
-symptomatic

OR
-if TSH>10
-2 readings

Question 9

which blood test is used to monitor effectiveness of levothyroxine?

Answer 9

TSH

Question 10

What cancer is hashimotos associated with?

Answer 10

MALT lymphoma

Question 11

If TSH high, T4 normal, it can indicate subclinical hypothyroid OR…

Answer 11

poor compliance with levothyroxine

Question 12

toxicity of which drug may cause hypothyroidism

Answer 12

lithium

Question 13

side effects of thyroxine therapy

Answer 13

hyperthyroidism
reduced bone mineral density
worsening of angina
A fib

Question 14

management of myxoedemic coma

Answer 14

IV thyroxine and hydrocortisone