Hyppthalamic Hormones Flashcards

(30 cards)

1
Q

Paraventriculer nucleus site
Within th BBb or outside

A

Adjacent of the 3rd ventricle
Within the BbB

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2
Q

Paraventriculer nucleus have to types of neurons

A

Magnocelluler ADH and oxytocin
Parvocelluler ADH TRH CRh

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3
Q

Paraventriculer nucleus hormones

A

CRH
TRH

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4
Q

Arcuate nucleus

A

Dopamine and GHRH

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5
Q

Preoptic nucleus

A

GRH

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6
Q

Periventrinculer nucleus

A

Somatostatins

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7
Q

Supraoptic and Paraventriculer

A

ADh and oxytocin ‘
ADh supraoptic parvo and mango
Oxytocin Paraventriculer parvocelluer ,

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8
Q

Define dopamine

A

Prolactin inhibiting hormone

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9
Q

How many receptors does dopamine have

A

5 receptors

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10
Q

Dopamine is produced in 3 sites

A

Substantia nigra
Arcuate nucleus
Medulla of the adrenal glands

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11
Q

Mention 5 functions for dopamine

A

1 ) have a role in behavior , cognition , voluntary movements
2) inhibits prolactin
3 inotropic
4 chronotropic ‘5bstimulate comiiting via chemoreceptors trigger zone

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12
Q

What’s metoclopromide

A

Is dopaminergic receptor antagonist

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13
Q

Can dopamine cross the BBB

A

It’s can’t cross the BBB .

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14
Q

Dopamine is metablized by

A

COMT
mAo

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15
Q

GNrH is secreted by which nucleus

A

Preoptic nucleus

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16
Q

GNrH secretion pattern

A

Pulsation manner

17
Q

When is GNrH secretion pattern is pulstile frequency high and when is low

A

High in the follicular phase
Low in the late luteal phase

18
Q

Half life of GNrH

19
Q

GNrH gene present on which chromosome

A

On chromosome 8

20
Q

Relation between GNrH , insulin and prolactin

A

Insulin increases GNrH activity
Prolactin decreases GNrH activity .

21
Q

Activity of the GNrH in th childhood

22
Q

Describe somatostatin اكتر اشي بميزه

A

Somatostatin is GHRH inhibitor
And inhibit TSH as well .

23
Q

Somatostain is secreted by

A

Intestine
Stomach
Pancreatic cells D cells
Thyroid cell parafolliculer cell s
Periventriculer cells

24
Q

What does somatostatin inhibits

A

1 GH
2 tsh
3 gastric emptying intestinal motility
Suppresses release of pancreatic hormone
Inhibits
Gastrin
Cck
Motility
Secretin
Insulin
Glucagon
VIP vasoactive intestinal peptide .

25
TRH released from And stimulate release of
From the Paraventriculer nucleus Secret the release of TSH , prolactin
26
Melatonin is derived from
Serotonin
27
Describe the activity of melatonin
Bio rhythmic and diurnal
28
What increase release of the melatonin
Darkness Hypoglycemia
29
Sites of melatonin production
👁️ retina , lens of the eye 👁️ , GIT , pineal gland , suprachiasmatic nucleus .
30
Gonadotrophins and melatonin relation
Melatonin inhibits gonadotrophins .