I - Cell Injury, Cell Death and Adaptations Flashcards Preview

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Flashcards in I - Cell Injury, Cell Death and Adaptations Deck (105)
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Foci of dystrophic calcification which appears as lamellated configurations because of their resemblance to grains of sand. Seen in some types of papillary cancer.

Psammoma bodies (TOPNOTCH)


Jaundice is due to accumulation of what pigment?

Bilirubin. (TOPNOTCH)


What type of necrosis is most characteristic of ischemia involving the heart or kidney?

Coagulative necrosis (TOPNOTCH)


What type of necrosis is most often caused by sudden ischemia from vascular occlusion?

Coagulative necrosis (TOPNOTCH)


A 56 y/o man died after 24-hour hospitalization for severe crushing chest pain. The type of necrosis of myocardium will most likely reveal:

Coagulative necrosis (TOPNOTCH)


The kidney in nephrocalcinosis is an example of what type of calcification? Dystrophic or metastatic?

Metastatic calcification (TOPNOTCH)


Dystrophic or metastatic calcification? Calcific aortic stenosis

Dystrophic calcification(TOPNOTCH)


Dystrophic or metastatic calcification?Left anterior descending coronary artery with atheromatous plaques

Dystrophic calcification(TOPNOTCH)


Dystrophic or metastatic calcification? Sarcoidosis

Metastatic calcification (TOPNOTCH)


Dystrophic or metastatic calcification? Paget disease

Metastatic calcification (TOPNOTCH)


After a tibial fracture in a 19 year old football player, the leg is immobilized to permit healing. The leg muscles decrease in size due to: (A) decrease in cell size, (B) decrease in cell number, (C) inadequate nutrition, (D) loss of hormonal stimulation

decrease in cell size (atrophy) (TOPNOTCH) Robbins Basic Pathology, 8th ed. P. 4


A 30 year old thalassemic male has been receiving multiple blood transfusions throughout his life. What is the expected intracellular accumulation in the parenchymal cells of his liver, heart, and endocrine organs?

Hemosiderin(TOPNOTCH)Robbins Basic Pathology, 8th ed. p.26


An 80 year old female is found to have calcified aortic valves. Which of the following is the likely cause? (A) renal failure with secondary hyperparathyrodism, (B) accumulation of calcium in damaged valves despite absence of calcium derangements, (C) parathyroid-related protein production from an underlying malignancy, (D) hypercalcemia from multiple myeloma

Accumulation of calcium despite absence of calcium derangements (dystrophic calcification) (TOPNOTCH) Robbins Basic Pathology, 8th ed. Pp26-27.


In industrialized nations, what are the most common causes of fatty change in the liver?

Alcohol abuse and diabetes (TOPNOTCH) Robbins Basic Pathology, 8th ed. P 23.


A 22 year old female is on the first day of her menses. Which of the following characterizes the events in her endometrial cells: (A) endometrial cells show shrinkage and nuclear condensation, (B) neutrophils accumulate around the cells, (C) severe mitochondrial swelling and plasma membrane destruction, (D) accumulation of amorphous pink material

Endometrial cells show shrinkage and nuclear accumulation (Apoptosis) (TOPNOTCH) Robbins Basic Pathology 8th ed., pp 19-20