IBD/diverticular/toxic mega Flashcards
(32 cards)
where does UC affect
colon
where does crohns affect
can do whole GI tract
smoking and IBD
increases chance of crohns
reduces risk of UC
mental that may influence IBD
stress and depression can preceed episodes
difference in location pattern of UC and crohns
crohns - skip lesions
UC - continuous
what is cobblestone appearance
deep ulcers and fissures in crohns
where is the inflammation in crohns
transmural
transmural
across the entire wall of an organ or blood vessel
where does UC begin
rectum and extends
feature of UC lumen
red mucosa and bleeds easy
where is the inflammation in UC
mucosal
which IBD has a high chance of granulomas
crohns
microscopic findings of UC
Goblet cell depletion
Crypt abscesses
what is IBD
innapropriate immune response to things in the lumen
in the IBD pathophys which cells take over
effector T cells predominating over regulatory T cells.
what do the effector T cells release
proinflammatory cytokines
what do the proinflmmatory cytokines do
promote macrophages to release TNF
most common site for crohns
ileocaecal
colon crohns symptoms
diarrhoea, bleeding and pain related to defecation
UC presentation
diarrhoea, often containing blood and mucus
why might you see anaemia on blood test
normocytic normochromic anaemia of chronic disease
or cant absorb B12
Crampy abdominal pain relieved by defecation or wind
IBS
common symptoms of IBS
altered bowel habit, a sensation of incomplete evacuation, abdominal bloating
diverticular formation
mucosa extrude through the colonic muscular wall
