IC3 Geriatric Syndromes Flashcards

(44 cards)

1
Q

fried frailty tool

A

1) weak = poor hand grip strength, difficulty walking up 1 flight of stairs

2) slow walking (>6-7 sec to walk 10ft)

3) low phy activity

4) weight loss (≥5% in last year)

5) exhaustion (fatigue when performing daily activities)

1-2 = pre frail
≥3 = frail

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2
Q

FRAIL scale

A

Fatigue
Resistance (difficult climbing 1 flight of stairs)
Ambulation (walking one block, 80m)
Illness (>5 illness of HTN, DM, cancer, chronic lung disease, asthma, heart attack, CHF, stroke, arthritis, KD)
Loss of weight (>5 % in past yr)

1-2 pre frail
≥3 frail

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2
Q

likely pathophysiology of frailty

A

combination of genetic and environmental factors = increased inflammation, neuroendocrine dysregulation = increased CRP and IL6 / change in growth or sex hormones = anorexia, sarcopenia, cognition, clotting… etc .

eventually results in slowness, weakness, weight loss, low activity, fatigue…

not inevitable part of ageing

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2
Q

Interventions for frailty (purpose, when and wat)

A

for cfs 4 and 5
to slow down/reverse progression

1) what matters most = goals of therapy

2) physical exercise, occupational therapy (resistance type to reduce muscle loss/improve function)

3) nutritional intake

4) med review
- any DRP affecting physical therapy and nutrition
- vit D supplementation

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3
Q

why are OPIOIDS included in stoppfall (when to remove)

A

remove IF

slow reaction, sedation, impaired balance

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3
Q

types of dizziness

A

vertigo
- sensation of motion without moving

pre syncopal dizziness
- postural hypo = dizzy/unstable

dysequlibrium
- walking unsteadiness

unspecified dizziness
- light headnedness

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3
Q

what are falls risk increasing drugs (FRIDs)

MECHANISM?

A

sedation
- reduced awareness of environmental hazards

orthostatic
- perfusion to brain , eye, leg is limited = weakness in legs = give away
- poor baroreflex

anticholinergics

hypoglycaemia

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4
Q

why are DIURETICS included in stoppfall (when to remove)

A

remove IF

OH, hypotension, electrolyte disturbance, urinary incontinence?

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4
Q

considerations for nutritional intake in frailty intervention

A

oral nutritional supplements
- milk feeds? enteral feeds?
- vit D?

medi SE
- affect taste? sedation?
eg anticholinergic affect taste reduce appetite = affect swallowing

depression
- not eating (untreated/not treated properly)

access to food
- unable to buy food
- not enough money to buy nutritional food
(causes obesity)

swallowing/chewing
- affected by dementia, lack of teeth, etc.

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4
Q

risk assessment for falls (simple) (AGS/BGS)

A

1) obtain relevant PMH, PE, cognitive and functional assessment

2) determine multifactorial fall risk:
- hx of falls
- medications
- gait, balance, mobility
- visual acuity
- other neurological impairments
- muscle strength
- HR and rhythm
- postural hypotension
- feet / footware
- environmental hazards
- hearing impairment

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4
Q

why dizziness is an important geriatric syndrme>?

A

1) may be the result of potentially serious etiologies (stroke, MI, traumatic brain injury)

2) increased fall risk

3) increase reconditioning risk (= less likely to move + discomfort with dizziness = decondition = reduce QOL and socially withdrawn)

4) reduced QOL

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5
Q

FRIDs drugs –> stoppfall

what are the drugs listed

A

OH: alpha blockers, central antihypertensives (methyldopa), vasodilators (nitrates), diuretics (baroreflex)

opioids

psych: antidepressants (TCA), antipsychotics, benzodiazepines, z hypnotics.

AEM: ataxia

anticholinergics: first gen antihistamines, muscle relaxants

OTHERS: oral hypoglycaemic (SU higher risk)

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6
Q

why are ANTIDEP included in stoppfall (when to remove)

A

remove if
hyponatremia, OH, dizziness, sedation

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7
Q

key points for dizziness and implications

A

high proportion due to age

high proportion with dizziness lasting several minutes at most
= medication management may not have benefit (takes time to take effect)

high proportion with serious etiology

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8
Q

approach to evaluating dizziness

A

TiTraTE

timing = continuous or episodic (onset, freq, duration)
triggers = head movement, posture change
targeted examination

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9
Q

classification of dizziness (differential diagnosis)

A

episodic triggered (e.g., dix hall pike manoeuvre)
= positive = beneign paroxysmal positional vertigo
= negative = orthostatic hypo

episodic Spontaneous: further history
= Unilateral hearing loss/sensation of ear fullness: Meniere Disease
= Migraine Headache: Vestibular Migraine
= Psychiatric symptoms: Panic attack, etc

continuous vestibular
= Trauma/toxin (drugs)

continuous spontaneous: HINTS Exam [Head Impulse/Nystagmus/Test of Skew]
= Central: Stroke/TIA
= Peripheral: Vestibular neuronitis

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10
Q

how to manage dizziness

when should vestibular suppressants be used

A

if vestibular symptoms are prolonged (>30 min)

because all the drugs are beers list = need review
- assess risk vs benefit and stop ASAP when possible.

consider non phx intervention such as vestibular rehab

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10
Q

list of vestibular suppressants

A

antihistamines
phenothiazines
anticholinergics
benzodiazepines
antidopaminergic
calcium channel antagonist
histamine analogues

10
Q

anticholinergic vestibular suppressants

A

FG antihistamine = diphenhydramine, dimenhydrinate, meclizine

anticholinergic
- scopolamine (hyosicne hydrobromide)

phenothiazine
- prochlorperazine, promethazine

10
Q

BZP vestibular suppressants

A

lorazepam
diazepam
clonazepam
x a few days

  • sedating
  • risk of falls
  • cognitive impairment
  • depression
11
Q

calcium channel antagonists vestibular suppressants

A

cinnarizine (and flunarizine)
- increase circulation to the cochlear

  • sedating
  • weight gain (increased appetite?)
  • caution in parkinsonism
12
Q

antidopaminergic vestibular suppressants

A

metoclopramide
ondansetron (if contraindication to meto)

  • more for N/V
13
Q

histamine analogue vestibular suppressants

A

betahistine

type 3 histamine receptor antagonist, partial H1 receptor agonist (no effect on H2)

  • caution in asthma
  • c/I active or pmh PUD
14
Q

potential list of drugs that may cause dizziness (pertenint drugs only and their mechanism)

A

drugs with cardiac effects: hypotension , TDP, OH, arrhythmia

anticholinergic effect (central)

cerebellar toxicity = BZP, AEM, lithium

hypoglycaemia

ototoxicity = aminoglycosides, antirheumatic agents

bleeding complications (anticoagulants) and bone marrow suppression (anti thyroid meds)

15
what are the delirium subtypes
hyperactive delirium - agitation - inattention - psychosis hypoactive delirium - slow response - increased sedation (associated with worse outcomes)
16
4at detection of delirium
16
risk factors for delirium
>65yo cognitive impairment and/or dementia current hip fracture severe illness
17
etiologies for delirium
I WATCH DEATH Infection Withdrawal (alcohol, barbiturates, BZP) Acute metabolic disorder (electrolyte imbalance, hepatic/renal failure) Trauma CNS (stroke, haemorrhage, tumour, seizure, pD) Hypoxia (anemia, HF, pulmonary embolus) Deficiency (b12, folic, thiamine) Endocrinopathy (thyroid, glucose, parathyroid, adrenal) Acute vascular shock (shock, vasculitis, hypertensive encephalopathy) Toxins, substance use, medications Heavy metals (arsenic lead mercury)
17
drugs commonly associated with delirium
strong anticholinergic benzodiazepine z hypnotics opioids H2RA others: = antimicrobials* (FQ, cefepime) - must renal adjust = GC = dopamine agonists* (ropinirole, pramipaxole) = AEM* (particularly levetiracetam) = TCA = muscle relaxants = lithium* (if not used properly can change patient's neuropsychiatric condition).
18
delirium prevention strategies
sensory function optimisation nutrition hydration bowel movement / urination early mobility pain control med review social interaction with loved ones reorientation w/clock/calendar/proper lighting conducive environment good sleep infection/hypoxia management
19
what labs to cover when managing delirium
CBC = leukocytosis, anemia glucose = hypoglycaemia electrolyte imbalance renal (creatinine, BUN) = indicates drug excretion urinalysis = infection spO2 = hypoxia
20
phx management of delirium
last resort only if interferes with QOL only sparingly for short period of time only for hyperactive delirium (do not give for hypo, address underlying causes) = SC/IM/PO haloperidol 0.3 - 1 mg BD (up to 5mg/day) = atypical antipsychotics (quetiapine PO 6.25 - 12.5 mg BD up to100mg/day) (olanzapine PO 1.25-2.5mg up to 10mg/day) = BZP first line for alcohol or benzodiazepines wihdrawal (lorazepam 0.5 -1 mg)
20
what is stress incontinence (and common causes)
involuntary loss of urine due to increased intra abdominal pressure (coughing exercise laughing) weak pelvic floor muscle (childbirth, pregnancy, menopause) post urologic surgery, urethral sphincter weakness
21
what is urge incontinence (and common causes)
leakage of urine because of inability to delay voiding after sensation of bladder fullness is perceived - detrusor overactivity - local genitourinary conditions (tumours) or cns disorders (stroke, PD, dementia)
22
what is functional incontinence (and common causes)
urinary accidents - cognitive impairment e.g dementia - phyiscal impairment - psych unwillingness - environmental barriers
22
what is overflow incontinence (and common causes)
leakage of small amt of urine by (i) mech forces on over distended bladder = stress leakage (ii) effects of urinary retention on bladder and sphincter function = urge leakage - anatomic obstruction (prostate, stricture, cystocele); - acontractile/underactive bladder (DM, spinal cord injury) - neurogenic - medication effect
22
differential diagnosis of UI
DIAPPERS delirium infection (acute UTI) atrophic vaginitis (assoc with menopause) pharma (drugs) psych (depression) excessive urine output (hyperglycaemia) reduced mobility (functional incontinence) stool impaction
23
drugs that can cause or worsen UI
Allergy - antihistamines (FG) - decongestants analgesic - benzo - opioids anticholinergic - antimsucarinic - anciholinergic anti PD cardio - acei - diuretics - alpha blocker psych - antidepressant - antipsychotics others - SMR - estrogen - alcohol and caffeine - calcium channel blockers - GABAnergic (gabapentin, pregabaline) - thiazolidinediones (Pioglitazone)
24
management of UI algorithm (general)
1) address underlying cause 2) non phx - lifestyle mod [weight loss, normal bowel habit, reduce bladder irritant foods (caffeine), water hygiene] - bladder retraining (more for cognitively intact pt) - kegel pelvic floor muscle exercise (strengthen pelvic floor) - timed voiding (q1-2 hours) CONTINUE EVEN IF ON MEDS
25
management of stress UI
kegel pelvic floor muscle exercise topical estrogen (up to 3 months onset, caution women with PMH breast cancer) duloxetine (esp if depression present, c/I crcl <30) surgery? devices? e.g., estradiol ring got eormn
26
management of urge UI
kegel pelvic floor muscle exercise treat BPH topical oestrogen b3 adrenergic receptor agonist (mirabegron, vibegron) antimsucarinics - Solifenacin, darifenacin (risk of anticholinergic SE) botulinum toxic injection (bladder emptying SE) sacral nerve stimulation
26
management of overflow UI
if bladder outlet obstruction - men: treat BPH if bladder under activity - men and women: bethanechol +/- clean intermittent cathetirzation (CIC)
27
types of elder abuse
physical (chemical or physical restraint) sexual psych neglect financial
28
risk factors for elder abuse
dementia - bpsd = caregiver stress physical disability poor relaitonship with caregiver pre morbid caregiver with mental health issues *substance abuse, depression caregiver dependent on victim for material gains caregiver who feels overwhelmed caregiver is a victim of domestic violence