Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

ICM Exam 2 Rheumatology (MC) > ICM - Rheum 3 > Flashcards

ICM - Rheum 3 Flashcards

(56 cards)

Start Studying
1
Q

most common drugs that cause SLE

A

procainamide, hydralazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

possible environmental factors that can trigger SLE

A

molecular mimicry, drugs, hair dye, tobacco smoke, UV light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

possibly occurs in SLE due to Ab to cell membrane

A

hemolytic anemia, thrombocytopenia, leukopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

these are damaged in SLE due to immune complex deposition

A

blood vessels and kidneys

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ab to this in SLE will cause prolonged PTT, venous/arterial thrombosis, fetal distress, livedo reticularis, and thrombocytopenia

A

phospholipid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

this occurs from SLE Ab to brain constituents

A

lupus cerebritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most common cause of death in lupus patient

A

infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

systemic manifestation of SLE

A

fever, weight loss, morning stiffness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

skin manifestations of SLE

A

sun sensitive/butterfly rash, maculopapular rash, vasculitis, alopecia, oral ulcers, discoid, subacute cutaneous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

skin condition in 19% SLE….sharply defined papule and plaques (raised border) –> central area become atrophic/central clearing (*scars*)

A

discoid lupus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

hardening of skin by abnormalities of microvasculature and large vessels and fibrotic changes in muscles, joints, viscera

A

scerloderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

potent vasoconstrictors that are important in pathogenesis of scleroderma

A

endothelins, NO, EDCF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what are targeted in scleroderma?

A

endothelial cells (vascular endothelium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

early phase of scerloderma

A

edematous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

classic phase of scleroderma

A

indurative/sclerotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

pulmonary manifestations of scleroderma

A

interstitial fibrosis, dyspnea, pulmonary HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

GI manifestations of scleroderma

A

esophageal dysmotility, malabsorption (duodenum and jejunum), colonic wide sacculations, biliary cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

possible cardiac manifestation of scleroderma….secondary R heart failure due to pulmonary HTN

A

cor pulmonale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

cardiac manifestations of scleroderma

A

pericardial effusion and cor pulmonale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

renal manifestations of scleroderma

A

progressive arterial lesions (intimal proliferation, medial thinning, fibrosis) that decrease GFR, sudden collapse GFR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

markers that may signify renal problems (arterial lesions causing decreased blood flow, sudden collapse GFR) related to scleroderma

A

proteinuria, HTN, azotemia, microangiopathic hemolytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

spots on skin that may appear in scleroderma

A

telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

band of sclerotic induration and hyperpigmentation occuring on single extremity or face

Study These Flashcards
A

linear scleroderma

24
Q

DDX for scleroderma

Study These Flashcards
A

scleredema, scleromyxedema, eosinophilic fasciitis, toxic syndromes

25
classic triad of fibromyalgia
widespread pain (achy/burning in muscle), fatigue, sleep disorder
26
9 trigger points of pain in fibromyalgia (all bilateral)
occipital, low cervical, trapezius (midpoint upper border), supraspinatus, 2nd costochondral junction, lateral epicondyle, upper/lateral gluteus, greater trochanter, medial fat pad knee
27
how many pain/trigger points are necessary for diagnosis of fibromyalgia?
11/18/2015
28
lab tests that may help look for uderlying causes of fatigue/achiness in fibromyalgia patients
CBC (anemia, leukemia), CMP (diabetes, liver, kidney), CPK (muscle breakdown), ESR (inflammation), TSH (Hypo)
29
possible treatments of peripheral pain generators
CV exercise, heat/ROM, rubs, manipulative therapies (chiropractic, massage), analgesics/injections
30
meds usually used to treat fibromyalgia
tricyclic antidepressants (NE and serotonin reputake inhibitor)
31
responsible for problems associated with scleroderma
large amounts of collagen
32
arthritis that affects men and women at same rate
psoriatic
33
look for skin changes in these areas for psoriasis
periumbilical area, elbow, intragluteal fold, nail pitting
34
these cause symmetric polyarthritis
RA and SLE
35
this arthritis involves DIPs
OA
36
commonly to see this on hand Xray in psoriatic arthritis
pencil in cup deformity
37
enteropathic causes of arthritis
ulcerative colitis, Chron's disease, reactive arthritis, bowel bypass disease, whipple's disease
38
ulcerative colitis and Chron's disease have been associated with this kind of arthritis
ankylosing spondylitits
39
relapsing syndrome of oral ulceration, genital ulceration, and uveitis --\> could cause arthritis
Bechet's disease
40
common finding on Xray in enteropathic arthritis
sacroiliitis
41
5 different types of psoriatic arthritis
DIP involvement, peripheral asymmetric oligoarthritis, rheumatoid like, arthritis mutilans, sacroiliitis
42
account for 10-30% of nongonoccal bacterial arthritis (usually from skin or soft-tissue infection)
B-hemolytic strep
43
gram negative bacteria that most commonly cause septic arthritis in IV drug users
S marcescens and P aeurgionsa
44
common gram negative bacteria that cause septic arthritis in elderly (from skin or UTI)
E coli
45
aka vertebral body TB
Pott's disease
46
may need this to diagnose TB related septic arthritis
synovial biopsy
47
where are organisms located in joint in septic arthritis?
subsynovial space
48
clinical features of septic arthritis
warm, swollen painful joint with constitutional symptoms
49
arthritis that most resembles septic arthritis (monoarticular)
gout and pseudogout
50
treatment for G+ coccal septic arthritis (after aspiration)
naficillin or first gen cephalosporin
51
antbiotic for G- cocci (gonnorhea) septic arthritis after aspiration
ceftriaxone
52
antibiotic for G- rod septic arthritis
aminoglycoside
53
clinical presentation of gonoccal arthritis
migratory polyarthralgia (3-5 joints), tenosynovitis, dermatitis, fever
54
DDX for septic arthritis (rash and arthritis)
SLE, lyme disease, bacterial endocarditis, N meningitidis
55
typical antibiotic used in disseminated gonococcal infection
penicillin
56
these 2 synovial fluid classifications are friable
inflammatory and septic

ICM Exam 2 Rheumatology (MC) (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions