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ID Flashcards

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1
Q

Tetracycline common side effect (1)

A

Photosensitivity

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2
Q

Nematodes (eg lava migrans) Management (2)

A

Thiabendazole

Albendazole

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3
Q

Tetanus management (3)

A

Supportive ventilation - support and muscle relaxants
IM tetanus immunoglobulin - for high risk wounds
Metronidazole

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4
Q

Syphilis is caused by what organism?

A

Treponema pallidum

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5
Q

Strongyloides stercoralis
Features (3)
Management (2)

A

A) papulovesicular rash soles feet and buttocks, Abdo pain, diarrhoea
B) ivermectin, albendazole

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6
Q

Diphtheria
Features(4)
Management (2)

A

A) sore throat, grey appearance tonsils , bulky lymphadenopathy, heart block
B) penicillin, antitoxin

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7
Q

Penile ulcers
A) painful
B) painless

A

A) chancroid (single,deep, lymphadenopathy), herpes (multiple, superficial, nil lymphadenopathy)

B) syphilis

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8
Q

Leptospirosis Mx

A

Doxy or benpen

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9
Q

Chickenpox in pregnancy management
A) if nil immunity
B) if symptomatic

A

A) Varicella zoster Ig - VZIG

B) aciclovir

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10
Q

Damgue fever
Features (5)
Management

A 
A) Retro orbital headache 
Rash (maculopapular)
Fever
Thrombocytopenia
Leukopenia

B) supportive measures

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11
Q

Lyme disease
A) features - i) early ii) late
B) investigation
C) management

A

A) erythema migrans “bulls eye” rash, headache fevers, lethargy
Late: heart block, facial nerve palsy, meningitis
B) Elisa test - borrelia burgdorferi
C) Doxycycline if early, ceftriaxone if severe

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12
Q

Lyme disease
A) features - i) early ii) late
B) investigation
C) management

A

A) erythema migrans “bulls eye” rash, headache fevers, lethargy
Late: heart block, facial nerve palsy, meningitis
B) Elisa test - borrelia burgdorferi
C) Doxycycline if early, ceftriaxone if severe

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13
Q

Severe features of malaria (7 Inc complications)

A 
Acidosis 
Parasitemia >2%
Shizonts on blood film
Hypoglycaemia 
Temp >39
Severe anaemia 
Complications - cebebral malaria, renal failure, ARDS, DIC
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14
Q

Leprosy
A) features (2)
B) Mx (3)

A

A) hypopigmented skin lesions, sensory neuropathy

B) rifampicin, clofazimime, dapsone

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15
Q

Leprosy
A) features (2)
B) Mx (3)

A

A) hypopigmented skin lesions, sensory neuropathy

B) rifampicin, clofazimime, dapsone

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16
Q

Measles
Features (5)
Mx

A

A) koplick spots - white spots on buccal mucosa
Rash on face, coryza, conjunctivitis, fever

B) supportive, inform public health

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17
Q

Inactived vaccines (3)

A

Hepatitis A
Influenza
Rabies

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18
Q

Toxins vaccines (3)

A

Pertussis
Tetanus
Diphtheria

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19
Q

Conjugate vaccines - links the poorly immunogenic bacterial polysaccharide outer coats to proteins to make them more immunogenic (5)

A 
Pneumococcus
Meningicoccus
Hepatitis b 
Haemophillis 
Human pappilovirus
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20
Q

Gonorrhea (gram neg diplococcus) management

A

IM ceftriaxone stat

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21
Q

Shigella Mx

A

Self limiting

If severe, immunocompromised- ciprofloxacin

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22
Q

HIV, neuro symptoms, single brain lesions with homogenous enhancement

A

CNS lymphoma

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23
Q

Tetanus Mx post wound
A) fully vacc < 10 years
B) fully vacc > 10 years or never been vacc

A

A) no Vax or If
B) low risk wound - booster
High risk wound - Ig + booster

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24
Q

Ando pain, diarrhoea, streaky rash ? And Mx

A

Strongyloides

Ivermectin

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25
Non specific (non gonococcal) urethritis Mx
1 week doxy
26
Non specific (non gonococcal) urethritis Mx
1 week doxy
27
Anthrax (painless black scab, lymphadenopathy) Mx
Ciprofloxacin
28
Lyme disease Mx Early Late
A) doxy | B) iv ceftriaxone
29
Following treatment for syphilis: TPHA remains ?, VDRL becomes ?
Successful treatment for syphillis TPHA - positive VDRL - negative
30
mycoplasma pneumonia features (1) chest x ray (1) Ix (1)
erythema multiforme - "target lesions" bilateral consolidation Serology
31
pelvic inflammatory disease Mx
ofloxacin + metronidazole
32
Genital warts Mx (3)
Single - cryotherapy Multiple - Topical Podophyllum 3rd line - Topical Imiquimod
33
Schistosomiasis Mx
Praziquantel
34
Active Tb Mx
first 2 months - RIPE - Rifampicin, Isoniazid, Pyrazinamide, Ethambutol continuation - Rifampicin, isonazid
35
Latent Tb Mx
3 months Isonazid + Rifampicin OR 6 months isoniazid
36
Renal infection + fever = ?
Cytomegalovirus
37
Mycobacterium avium complex Mx A) prophylaxis (CD4 <100) B) Mx (normally CD4 <50)
A) clarithromycin or azithromycin | B) rifampicin, ethambutol + clarithromycin
38
Chlamydia Mx A) normal B) pregnancy
A) Doxycycline | B) if pregnant - azithromycin or amoxicillin
39
Nucleoside analogue reverse transcriptase inhibitors (NRTI) A) example B) mechanism C) common s.e
A) "ine", zidovudine, abacavir, tenofovir B) prevent synthesis of dsViral DNA C) peripheral neuropathy
40
Non nucleoside reverse transcriptase inhibitors (NNRTI) A) example B) mechanism C) side effects
A) nevirapine, efavirenz (vir in middle) B) viral reverse transcriptase C) rash, p450 inducer
41
Protease inhibitor (PI) A) examples B) mechanism C) side effects
A) "navir" ending B) bind viral protease prevent viral replication C) p450 inhibitor, metabolic syndrome
42
Integrase inhibitor A) example B) mechanism C) side effects
A) "gravir" ending | B) prevents viral DNA from being inserted into host genome
43
Cat scratch disease organism
Bartonella henselae
44
Epiglottis bacteria
Haemophillis influenzae
45
Campylobacter Mx (2)
1. supportive | 2. Clarithromycin (if severe, eg >8 bloody stools/ day)
46
Live attenuated Vaccines (should not be given to immunocomprismised) (6)
``` Yellow fever Oral polio Intranasal influenza Varicella Measles, mumps and rubella (MMR) Tb (BCG) ```
47
Chlamydia Mx
Doxycycline
48
Gingivostomatitis (oral ulcers) cause
Herpes simplex
49
Pneumocystitis jiroveci pneumonia Mx
Co-trimoxazole
50
Toxoplasmosis Mx
1. Immunocompetent - self resolve | 2. Immunocompromised - Pyrimethamine + sulphadiazine
51
Primaquine MOA
used in non-falciparum malaria to destroy liver hypnozoites and prevent relapse
52
Most common viral meningitis cause
Coxsackie
53
Lyme disease Mx (2)
Doxycycline (amoxicillin if pregnant) | Ceftriaxone in disseminated disease
54
Leprosy Mx A) >6 lesions B) <6
A) rifampicin, dapsone and clofazimine for 12 month | B) rifampicin and dapsone for 6 months.
55
Chagas disease parasite association Mx
Trypanosoma cruzi Dilated cardiomyopathy Benznidazole
56
Leptospirosis Association Ix Mx
Sewage, farmer, abbatoir Serology Benpen/ doxy
57
Gonorrhoea Ix Mx
Microscopy: Gram neg diplococcus | Ceftriaxone
58
URTI + Amoxicillin = Rash | ?cause
Infectious Mononucleosis
59
Shigella Mx
Self resolve | Ciprofloxacin
60
Genital ulcers cause? a) painful b) painless
Painful: Herpes > Chancroid Painless: Syphilis > Lymphogranuloma Venerum
61
Amoebiasis Mx
Metronidazole (+ diloxanide, if invasive)
62
African trypanosomiasis (sleeping sickness) Mx
Pentamidine
63
Campylobacter Mx
Clarithromycin
64
Listeria Mx
Amoxicillin (+ Gentamicin, if meningitis)
65
post exposure prophylaxis Hepatitis B
a) fully vaccinated - booster | b) not fully vaccinated - HBIG + booster
66
Human/ Animal bites Mx
co-amox
67
Chickenpox Mx in pregnancy
1st - check antibodies 2nd a) immune i) <20 weeks - consider aciclovir with caution ii) >20 weeks + rash <24hours = aciclovir b) not immune i) <20 weeks - VZIG ii) >20 weeks - VZIG/ aciclovir
68
When to start antiretrovirals and PJP prophylaxis in HIV
ARV - ASAP | PJP - CD4 <200
69
Cat scratch disease organism
Bartonella henselae
70
Chronic hepatitis b treatment
Entecavir
71
post splenectomy infections
strep pneumoniae neiserria meningitidis H influenzae

MRCP (14 decks)

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