ID Flashcards

(52 cards)

1
Q

Bacterial meningitis empiric treatment

?hospital-acquired

A

Vanc/ceftriaxone (or cefotax)

+ amp (>50 yo)

If hospital acquired, then cefepime or merrem instead of 3rd gen ceph

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2
Q

Encephalitis + ovarian teratoma (50%)

Psych symptoms

Seizures

Autonomic instability

A

Anti-NMDA R encephalitis

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3
Q

Skin ulcer, evolve from painless nodules, in neutropenic patient

A

Pseudomonas (ecthyma gangrenosum)

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4
Q

Empiric tx for non-purulent and purulent cellulitis

A
  1. Dicloxacillin, cephalexin, clinda

2. Bactrim, clinda, doxy, minocycline, linezolid (iv vanc if bad)

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5
Q

Nec fasc treatment

A

Vanc
Imipenem
Clindamycin
Debride

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6
Q

Abscess < 5 cm treatment

A

I&D only

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7
Q

Bat & bird droppings

A

Histo

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8
Q

Rabbits

A

Franciscella

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9
Q

Bird exposure

A

Chlam. Psittaci

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10
Q

Pseudomonas RFs

A

Bronchiectasis
Pred > 10
Broad abx > 7 days in preceding month
Malnutrition

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11
Q

Tick bite
Fever
Lymphocytic meningitis
Petechial rash

Dx & Tx

A

RMSF

Doxycycline

Can have negative antibodies

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12
Q

Tick bite
Erythema migrans
Meningitis

Dx & Tx

A

Lyme

Doxycycline

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13
Q

HIV
Fever,chills,sweats,weight loss after starting therapy
LAD, HSM, anemia, leukopenia, increase ALP

Dx & Tx

A

DMAC and IRIS

Clarithromycin, ethambutol

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14
Q

Coccidioides meningitis

Tx

A

Fluconazole

Second - itraconazole

(Caspo does not penetrate CSF)

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15
Q

Neurosyphilis concerns

Next step…CSF or treat?

A

CSF studies

If positive, then IV PCN

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16
Q

TB treatment duration - reasons to prolong

A

2 mo initiation phase

4 mo continuation

7 mo continuation if:
No pyrazinamide
Cavitation and + sputum after initiation
Once weekly INH and rifapentamine and + sputum after initiation

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17
Q

5 mm positive PPD

10 mm positive PPD

15 mm positive PPD

A

Recent exposure
HIV +
Fibrotic changes on XR c/w old TB
Immunosuppressed > 15 mg pred for 4 weeks

IVDU
Homeless, prisons, LTAC
Recent immigration from country with high prevalence
Lab personnel 
Hospital workers

Anyone

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18
Q

Post-exposure PPx for HIV

Pre-exposure PPx

A

Tenofovir-emtracirabine + raltrgravir

Tenofovie-emtracitabine

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19
Q

Late complement deficiency

A

Recurrent meningococcal meningitis, gonococcal infections

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20
Q

CVID

A

Recurrent sinusitis, pneumonia

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21
Q

Classical complement deficiency

A

Infection with encapsulated bacteria (strep pneumonia) etc

22
Q

Brain abscess

  • from odontogenic source
  • from neurosurgical source

Tx

A

Penicillin + metronidazole
(Mixed organisms)

Vanc + Merrem (pseudomonas)/3rd gen ceph

23
Q

Uncomplicated cutaneous Anthrax

Systemic anthrax

Tx

A

Cipro/levaquin/moxi/doxy

Add one or two bacteriocidal agents (imipenem, rifampin, doxy)

24
Q

Astmptomatic bacteriuria in pregnancy

A

Treat it

Don’t use nitrofurantoin if <30 days from delivery

25
Varicella exposure PPx 1 Immunocompetent 2 Immunocompromised
Vaccine Immune globulin (pregnant women too) Give if 4 days within exposure
26
Cervicitis treatment PID treatment (requiring hospitalization)
Rocephin + axithromycin x 1 Cefotetan + doxy
27
Outdoors + fever + focal weakness
West Nile Get CSF Ab, not PCR
28
Sudden high fever + frontal/retro-orbital pain + myalgia/low back pain (break bone fever) followed by rash Usually travel history Leukopenia, thrombocytopenia, increased lft
Dengue
29
Pneumococcal schedule for immunocompromised and HIV
PCV-13 now PCV-23 8 weeks later
30
When is active TB not contagious
2 weeks of treatment Improved symptoms 3 negative sputum smears
31
Drug of choice for candidemia
Echinocandins
32
Signs / RFs for disseminated histo
Fever Weight loss HSM AIDS patient or heme malignancy Ohio river valley or Central America
33
Sinus infection Immunocompromised Septate hyphae with acute angle branching Positive galactomannan Ag
Aspergillus sinus infection Voriconazole
34
Rapid dementia + 14.3.3 protein in CSF Myoclonus
CJD
35
Small red dots starting in buccal mucosa - spreads to hands and face , then arms legs and feet Macules --> papules --> vesicles
Smallpox (variola)
36
Conjunctivitis Cough Coryza Then rash 2-4 days later (buccal white spots then morbilliform rash to face/neck then extremities)
Measles (rubeola)
37
Skin infection Nail salons - pedicure Rash 3-4 weeks after
Myco fortuitum | Marinum a/w fish tanks
38
RFs for drug-resistant strep pneumonia Treatment?
``` Age > 65 Alcoholism Immunosuppressive COPD Chronic liver or kidney disease Recent (3-6 months) beta-lactam, macrolide, or FQ abx ``` Moxi + Doxy / macrolide
39
Coinfectuon with Lyme Fever Thrombocytopenia Leukopenia
Anaplasmosis (anaplasma phagocyto)
40
Chlamydia treatment GC treatment
Azithro Or doxy or FQ Rocephin Or cefixime
41
Latent TB treatment
INH 9 months OR Rifampin 4 months
42
MAC treatment
Clarithromycin/azithromycin + ethambutal + rifampin/rifabutin
43
Fever Abd pain Constipation then diarrhea Bradycardia HSM Africa, Asia, Latin America Sometimes rash
Typhoid fever
44
Western Africa Fever Abd pain Headache Hemorrhage
Lassa fever
45
Travel to Arabian peninsula Respiratory illness with viral like syndrome Often progresses to pneumonia
Middle East respiratory syndrome
46
CAP coverage suspect pseudomonas
Beta lactam Aminoglycoside FQ
47
Crypto meningitis treatment
AMB + flucytosine Then flucytosine maintenance
48
Ohio river valley, Mississippi Pulmonary infection Skin or bone findings
Blasto
49
Ohio river valley, Mississippi Bad lung infection
Histo
50
Osteomyelitis + 1. Cat or dog bite 2. Foot puncture 3. Sickle cell patient 4. Vertebrae Organisms?
Pasteurella Pseudomonas Salmonella (or staph) Staph aureus
51
Mild babesiosis tx
Atovaquone and azithro
52
Severe babesiosis tx
Quinine and clinda