ID

Question 1

Mammal/human bite tx

Answer 1

• Amp/Sulbactam and then Amox/Clavulanic acid
• clinda + fluoroquinolone
• clinda+bactrim

Question 2

clindamycin uses

Answer 2

tx lung abscesses and femle genital tract infxns

Question 3

Legionnaire dz tx

Answer 3

erithryomycin, CAP

Question 4

bacterial meningitis empiric tx

Answer 4

IV ceftriaxone + vancomycin

Question 5

Pseudomonas tx

Answer 5

• imipenem/cilastatin
• cipro
• cefepime (4th gen cephs)
• gentamicin (AG)/amikacin/tobramycin
• aztreonam
• pip/tazobactam

Question 6

CF with Pseudomonas infxn tx

Answer 6

• multi-drug tx

- ceftazidime (3rd gen) or ticarcillin + gentamicin

Question 7

endocarditis tx

Answer 7

beta lactam + AG

Question 8

pharyngitis tx

Answer 8

beta-lactam: PCN, amox

Group A strep

Question 9

Lyme dz tx - nonpregnant

Answer 9

doxy

Question 10

Lyme dz tx - pregnant and <8yo

Answer 10

amox

Question 11

Scarlet fever tx

Answer 11

PCN V

gp A strep
erythro, first gen ceph, clinda

Question 12

cocci tx

Answer 12

fluconazole

Question 13

histo and blasto tx

Answer 13

itraconazole

Question 14

toxo

Answer 14

pyrimethamine, sulfadiazine, clinda

Question 15

why is cipro avoided in children?

Answer 15

cartilage destruction and growth retardation

Question 16

cellulitis tx

Answer 16

oral cephalosporins (cefazolin) or nafcillin

-Staph aureus, GAS

Question 17

Necrotizing fasciitis empiric tx

Answer 17

1. DEBRIDEMENT!
2. imipenem or meropenem +/- vancomycin
   - If strep or clostridia: PCN G + clinda

Question 18

Whipple dz tx

Answer 18

TMP-SMX x 1 yr

Question 19

Abx to avoid in pregnancy

Answer 19

doxycycline
fluoroquinolone!
TMP-SMX

Question 20

UTI tx in pregnancy

Answer 20

• amoxicillin
• nitrofurantoin
• cephalexin

Question 21

GBS pregnancy tx

Answer 21

IV beta-lactams (PCN, amp)
PCN allergic but only rash: cefazolin

PCN allergic w/ anaphylaxis: clinda, erythromycin, vanc

Question 22

IE tx

Answer 22

beta-lactam + AG

Question 23

Pertussis tx

Answer 23

Macrolide (erythro, azithro, clarithro) whenever suspected

Question 24

pneumovax vaccine indications

Answer 24

all > 65

<65 if smoker, immunocomp, DM, chronic lung or heart dz, asplenia

-revaccinate after 5 years if IC or asplenia

Question 25

Nocardia asteroides

Answer 25

gram positive, partially acid-fast, filamentous/branching aerobe in soil TMP SMX = tx -wt loss, fever, nt sweats, pulm

Question 26

Actinomyces tx

Answer 26

PCN G

Question 27

impetigo tx

Answer 27

- oral erythro, dicloxacillin, cephalexin, clinda | - TOPICAL mupirocin

Question 28

tx lyme dz/RMSF/erhlichiosis in pregnancy

Answer 28

chloramphenicol

Question 29

Common gram negative bacteria causing PNA

Answer 29

E coli, Klebsiella, Pseudomonas, Enterobacter, Proteus, Serratia, Acinetobacter -usually infants, elderly, alcoholics, IC (neutropenia)

Question 30

MOE tx

Answer 30

psuedomonas --> cipro

Question 31

IE ppx

Answer 31

single dose amox

Question 32

Who gets IE ppx

Answer 32

prosthetic valve, prior IE, unrepaired congenital heart defect

Question 33

PCP tx if PaO2<70

Answer 33

TMP AND ORAL PREDNISOLONE!!

Question 34

tx for cervicofacial actinomycosis

Answer 34

high-dose PCN 6-12 weks

Question 35

Blastomycosis

Answer 35

Ohio (South central, North central) -lungs, skin, bones, joints, prostate

Question 36

Histoplasmosis

Answer 36

Southeast, mid-Atlantic, central US -PNA, HIV

Question 37

Febrile neutropenic pts empiric tx

Answer 37

ceftazidime (3rd) or cefepime or imipenem or meropenem