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Flashcards in ID Deck (37):
1

Mammal/human bite tx

-Amp/Sulbactam and then Amox/Clavulanic acid

-clinda + fluoroquinolone

-clinda+bactrim

2

clindamycin uses

tx lung abscesses and femle genital tract infxns

3

Legionnaire dz tx

erithryomycin, CAP

4

bacterial meningitis empiric tx

IV ceftriaxone + vancomycin

5

Pseudomonas tx

-imipenem/cilastatin
-cipro
-cefepime (4th gen cephs)
-gentamicin (AG)/amikacin/tobramycin
-aztreonam
-pip/tazobactam

6

CF with Pseudomonas infxn tx

-multi-drug tx
-ceftazidime (3rd gen) or ticarcillin + gentamicin

7

endocarditis tx

beta lactam + AG

8

pharyngitis tx

beta-lactam: PCN, amox

Group A strep

9

Lyme dz tx - nonpregnant

doxy

10

Lyme dz tx - pregnant and <8yo

amox

11

Scarlet fever tx

PCN V

gp A strep
(erythro, first gen ceph, clinda)

12

cocci tx

fluconazole

13

histo and blasto tx

itraconazole

14

toxo

pyrimethamine, sulfadiazine, clinda

15

why is cipro avoided in children?

cartilage destruction and growth retardation

16

cellulitis tx

oral cephalosporins (cefazolin) or nafcillin

-Staph aureus, GAS

17

Necrotizing fasciitis empiric tx

1. DEBRIDEMENT!
2. imipenem or meropenem +/- vancomycin
-If strep or clostridia: PCN G + clinda

18

Whipple dz tx

TMP-SMX x 1 yr

19

Abx to avoid in pregnancy

doxycycline
fluoroquinolone!
TMP-SMX

20

UTI tx in pregnancy

-amoxicillin
-nitrofurantoin
-cephalexin

21

GBS pregnancy tx

IV beta-lactams (PCN, amp)
PCN allergic but only rash: cefazolin

PCN allergic w/ anaphylaxis: clinda, erythromycin, vanc

22

IE tx

beta-lactam + AG

23

Pertussis tx

Macrolide (erythro, azithro, clarithro) whenever suspected

24

pneumovax vaccine indications

all > 65

<65 if smoker, immunocomp, DM, chronic lung or heart dz, asplenia

-revaccinate after 5 years if IC or asplenia

25

Nocardia asteroides

gram positive, partially acid-fast, filamentous/branching aerobe in soil

TMP SMX = tx

-wt loss, fever, nt sweats, pulm

26

Actinomyces tx

PCN G

27

impetigo tx

-oral erythro, dicloxacillin, cephalexin, clinda

-TOPICAL mupirocin

28

tx lyme dz/RMSF/erhlichiosis in pregnancy

chloramphenicol

29

Common gram negative bacteria causing PNA

E coli, Klebsiella, Pseudomonas, Enterobacter, Proteus, Serratia, Acinetobacter

-usually infants, elderly, alcoholics, IC (neutropenia)

30

MOE tx

psuedomonas --> cipro

31

IE ppx

single dose amox

32

Who gets IE ppx

prosthetic valve, prior IE, unrepaired congenital heart defect

33

PCP tx if PaO2<70

TMP AND ORAL PREDNISOLONE!!

34

tx for cervicofacial actinomycosis

high-dose PCN 6-12 weks

35

Blastomycosis

Ohio (South central, North central)

-lungs, skin, bones, joints, prostate

36

Histoplasmosis

Southeast, mid-Atlantic, central US

-PNA, HIV

37

Febrile neutropenic pts empiric tx

ceftazidime (3rd) or cefepime or imipenem or meropenem